Looking Back on 2018

Happy New Year! As we enter 2019, a new year of innovation and achievement, let’s take some time to appreciate some of the wonderful things that took place in the Department of Chemistry during 2018.

Emory Biotech Consulting Club Kicks Off January 14th!

Emory University is proud to kick-off its new Biotech Consulting Club! The club is designed for graduate students interested in gaining skills in Biotech entrepreneurship, consulting, and project management. During the semester, interested candidates will be grouped into small teams and paired with Emory investigators (PIs) or local start-ups to provide thorough market analyses and develop early-stage ideas into preliminary business plans with executive summaries. This experience is intended to help students build a professional network, gain hands-on experience in a field outside of their own area of study, and expand potential career opportunities.

The first club event is to be held on January 14th to highlight the projects and introduce the project leaders for the inaugural cohort (Spring 2019). Keynote speakers will include Lee Herron, Vice President of Venture Development Georgia Research Alliance (GRA), and Cliff Michaels, Interim Executive Director of Emory Office of Technology Transfer (OTT). The meeting will take place in 360 Atwood Hall from 3:00 to 4:00.

Check out the flyer below or @EmoryBCC on Twitter for more information!

Click here to register!

 

 

Research from the Davies Lab Featured in Emory News

Research from the Davies Lab has recently been featured by Emory News in an article titled “Chemical Catalyst Turns ‘Trash’ to ‘Treasure'”. The article highlights the lab’s most recent catalyst discovery, their Nature publication, their scientific mission, and their involvement with the CCHF. The article even includes videos and clips of some of the fascinating science taking place between the walls of the Davies Lab.

From the article:

“Each of the catalysts are unprecedented, achieving a different kind of selectivity than has been seen before,” Davies says. “We’re developing a toolkit of new catalysts and reagents that will do selective C-H functionalization at different sites on different molecules.”

“We’ve achieved exquisite catalyst control that is beyond what people thought would be possible even two or three years ago,” Davies says. “It’s incredible what my students have been able to achieve.”

Click [here] to read the full article!

December Research Round-Up

Congratulations to our amazing research teams here in the Department of Chemistry for their publications this month!

Bowman Group

Babikov, D., Benoit, D., Bowman, J., Burd, T., Clary, D., Donovan, R., … & Kirrander, A. (2018). Quantum dynamics of isolated molecules: general discussionFaraday discussions.

Ban, L., Bowman, J., Bradforth, S., Chambaud, G., Dracinsky, M., Fischer, I., … & McCoy, A. B. (2018). Molecules in confinement in liquid solvents: general discussionFaraday discussions.

Qu, C., & Bowman, J. M. (2018). Assessing the Importance of the H2 (H2O) 2 3-Body Interaction on the Vibrational Frequency Shift of H2 in the sII Clathrate Hydrate and Comparison with ExperimentThe Journal of Physical Chemistry A.

Davies Group

Fu, J., Ren, Z., Bacsa, J., Musaev, D. G., & Davies, H. M. (2018). Desymmetrization of cyclohexanes by site-and stereoselective C–H functionalizationNature564(7736), 395.

Dyer Group

Zhao, J., Su, H., Vansuch, G. E., Liu, Z., Salaita, K., & Dyer, R. B. (2018). Localized Nanoscale Heating Leads to Ultrafast Hydrogel Volume-Phase TransitionACS nano.

Heaven Group

Kaledin, L. A., Kaledin, A. L., & Heaven, M. C. (2019). The electronic structure of thorium monoxide: Ligand field assignment of states in the range 0–5 eVJournal of computational chemistry40(2), 430-446.

Kindt Group

Zhang, X., Arce, J. G., & Kindt, J. T. (2018). Derivation of micelle size-dependent free energies of aggregation for octyl phosphocholine from molecular dynamics simulationFluid Phase Equilibria.

Lynn Group

McGill, T. L., Williams, L. C., Mulford, D. R., Blakey, S. B., Harris, R. J., Kindt, J. T., … & Powell, N. L. (2018). Chemistry Unbound: Designing a New Four-Year Undergraduate CurriculumJournal of Chemical Education.

Musaev Group

Fu, J., Ren, Z., Bacsa, J., Musaev, D. G., & Davies, H. M. (2018). Desymmetrization of cyclohexanes by site-and stereoselective C–H functionalizationNature564(7736), 395.

Salaita Group

Zhao, J., Su, H., Vansuch, G. E., Liu, Z., Salaita, K., & Dyer, R. B. (2018). Localized Nanoscale Heating Leads to Ultrafast Hydrogel Volume-Phase TransitionACS nano.

Chemistry Unbound Article Selected as ACS Editors’ Choice

In the Fall of 2017, Emory’s Department of Chemistry overhauled its undergraduate curriculum to introduce a more interdisciplinary approach to teaching chemistry. The new course structure, named Chemistry Unbound, was designed to weave concepts of traditional chemistry disciplines together, giving students a more comprehensive foundation of the field.

This curriculum reform was described in “Chemistry Unbound: Designing a New Four-Year Undergraduate Curriculum”, written with contributions from Tracy L. McGill, Leah C. Williams, Douglas R. Mulford, Simon B. Blakey, Robert J. Harris, James T. Kindt, David G. Lynn, Patricia A. Marsteller, Frank E. McDonald, and Nichole L. Powell. The article, which was recently published in the Journal of Chemical Education, has been selected by the ACS as “Editors’ Choice”. This recognition highlights the value of the publication as a significant contribution to the global scientific community.

We are so proud of the success of Chemistry Unbound! Congratulations who everyone who contributed to such a wonderful accomplishment!

Click [here] to read the article!

Research from the Bowman Group Featured on Cover of the Journal of Physical Chemistry

Congratulations to the Bowman lab for their recent publication, “Tag-Free and Isotopomer-Selective Vibrational Spectroscopy of the Cryogenically Cooled H9O4+ Cation with Two-Color, IR–IR Double-Resonance Photoexcitation: Isolating the Spectral Signature of a Single OH Group in the Hydronium Ion Core”.

Their article was featured on the cover of The Journal of Physical Chemistry.

Emory University News: Record-Breaking Research Funding

Emory University News recently published an article discussing the value and impact of the record-breaking research funding the University has been awarded this year. In fiscal year 2018, Emory University received $734 million in external research funding, increasing 17% from last year and setting the record for external funding support in the school’s history.

From the article:

 “I commend our faculty and our research leaders for this tremendous accomplishment,” says Jonathan S. Lewin, Emory vice president for health affairs and executive director of the Woodruff Health Sciences Center.“This result reflects a long-term, sustained effort to create meaningful positive impact on health and wellness through our faculty’s groundbreaking discoveries, improving the lives of patients here in Atlanta, across the nation, and around the world.” 

The article also mentioned the $20 million awarded to the Center for Selective C-H Functionalization (CCHF) to fund the next phase of their global effort towards revolutionizing organic synthesis. Huw Davies, director of the CCHF, was quoted:

“Our center is at the forefront of a major shift in the way that we do chemistry. This shift holds great promise for creating new pathways for drug discovery and the production of new materials to benefit everything from agriculture to electronics.”

Click [here] to read the full article!

November Research Round-Up

Congratulations to our amazing research teams here in the Department of Chemistry for their publications this month!

Bowman Group:

Chen, Q., & Bowman, J. M. (2018). Quantum approaches to vibrational dynamics and spectroscopy: is ease of interpretation sacrificed as rigor increases?Physical Chemistry Chemical Physics.

Yang, B., Zhang, P., Chen, Q., Stancil, P., Bowman, J. M., Naduvalath, B., & Forrey, R. C. (2018). Inelastic Vibrational Dynamics of CS in Collision with H2 Using a Full-dimensional Potential Energy SurfacePhysical Chemistry Chemical Physics.

Dunham Group:

Hong, S., Sunita, S., Maehigashi, T., Hoffer, E. D., Dunkle, J. A., & Dunham, C. M. (2018). Mechanism of tRNA-mediated+ 1 ribosomal frameshiftingProceedings of the National Academy of Sciences115(44), 11226-11231.

Rivera, S., Young, P. G., Hoffer, E. D., Vansuch, G. E., Metzler, C. L., Dunham, C. M., & Weinert, E. E. (2018). Structural Insights into Oxygen-Dependent Signal Transduction within Globin Coupled SensorsInorganic chemistry.

Hoffer, E. D., Maehigashi, T., Fredrick, K., & Dunham, C. M. (2018). Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscodingNucleic Acids Research.

Hill Group:

Sullivan, K. P., Wieliczko, M., Kim, M., Yin, Q., Collins-Wildman, D. L., Mehta, A. K., … & Hill, C. L. (2018). Speciation and Dynamics in the [Co4V2W18O68] 10-/Co (II) aq/CoOx Catalytic Water Oxidation SystemACS Catalysis.

Kaledin, A. L., Troya, D., Karwacki, C. J., Balboa, A., Gordon, W. O., Morris, J. R., … & Musaev, D. G. (2018). Key Mechanistic Details of Paraoxon Decomposition by Polyoxometalates: Critical Role of Para-Nitro SubstitutionChemical Physics.

Lian Group:

Clark, M. L., Ge, A., Videla, P. E., Rudshteyn, B., Miller, C. J., Song, J., … & Kubiak, C. P. (2018). CO2 Reduction Catalysts on Gold Electrode Surfaces Influenced by Large Electric FieldsJournal of the American Chemical Society.

Lutz Group:

Williams, E., Jung, S. M., Coffman, J. L., & Lutz, S. (2018). Pore engineering for enhanced mass transport in encapsulin nano-compartmentsACS synthetic biology.

Musaev Group:

Kaledin, A. L., Troya, D., Karwacki, C. J., Balboa, A., Gordon, W. O., Morris, J. R., … & Musaev, D. G. (2018). Key Mechanistic Details of Paraoxon Decomposition by Polyoxometalates: Critical Role of Para-Nitro Substitution. Chemical Physics.

Salaita Group:

Hong, J., Ge, C., Jothikumar, P., Yuan, Z., Liu, B., Bai, K., … & Palin, A. (2018). A TCR mechanotransduction signaling loop induces negative selection in the thymusNature Immunology, 1.

Weinert Group

Rivera, S., Young, P. G., Hoffer, E. D., Vansuch, G. E., Metzler, C. L., Dunham, C. M., & Weinert, E. E. (2018). Structural Insights into Oxygen-Dependent Signal Transduction within Globin Coupled SensorsInorganic chemistry.

Fontaine, B. M., Duggal, Y., & Weinert, E. E. (2018). Exploring the Links Between Nucleotide Signaling and Quorum Sensing Pathways in Regulating Bacterial VirulenceACS infectious diseases.

Wuest Group:

Kontos, R. C., Schallenhammer, S. A., Bentley, B. S., Morrison, K. R., Feliciano, J. A., Tasca, J. A., … & Minbiole, K. P. (2018). An Investigation Into Rigidity‐Activity Relationships in bisQAC Amphiphilic AntisepticsChemMedChem.

Shapiro, J. A., Varga, J. J., Parsonage, D., Walton, W., Redinbo, M. R., Ross, L. J., … & Goldberg, J. B. (2018). Identification of Specific and Non‐specific Inhibitors of Bacillus anthracis Type III Pantothenate Kinase (PanK)ChemMedChem.

Kilgore, M. B., Morrison, K. R., Wuest, W. M., & Chandler, J. D. (2018). Influence of pH on the reactions of heme peroxidase-derived oxidants with R19SFree Radical Biology and Medicine128, S101-S102.

NOBCChE Outreach at Marietta High School Science Night

On Thursday, November 1st, the National Organization for the Professional Advancement of Black Chemists and Chemical Engineers (NOBCChE) at Emory University attended Marietta High School for their annual Science Night. The event, featuring classroom demos and science fair projects, welcomed volunteers from local universities to share about their STEM opportunities.

The Emory NOBCChE representatives who attended the event spent the evening handing out flyers and engaging with enthusiastic students and parents over some particularly exciting carbon dioxide chemistry. With do-it-yourself lava lamps and bouncing soap bubbles, guests were both entertained and inspired to learn more.