Emory News: New Emory Initiatives Drive Innovation in the Basic Sciences

The Emory News Center recently published an article outlining a series of initiatives through which Emory University hopes to foster scholarly and research eminence. As part of its mission, titled “One Emory: Engaged for Impact”, Emory aims to inspire “Innovation through Scholarship and Creative Expression”. To achieve this goal, a Task Force on the Future of Basic Science Research was organized to identify how to maximize the success and impact of our research efforts.

This task force was co-chaired by Guida Silvestri and the Department of Chemistry’s own Dr. Huw Davies. Two priority research initiatives were decided upon as a result of this effort: “Biological Discovery through Chemical Innovation” and “From Molecular Pathogenesis to Global Pandemics”. Dr. Davies, along with Dr. Haian Fu, leads the “Biological Discovery through Chemical Innovation” initiative with the aim of accelerating the development of the next generation of research tools, effective and safe drugs, and diagnostic agents.

“The idea is to enhance molecular science at Emory broadly,” says Davies. “The focus is not just on the potential for developing drugs, but on achieving more impactful basic science by deepening knowledge of biology and novel chemistry.”

To read the entire article, click [here].

Congratulations, 2018-2019 Graduates!

On Monday, May 13th, the Department of Chemistry celebrated the graduation of 104 undergraduate chemistry majors and 21 new PhDs. Congratulations to all of our graduates!

Afoma Deborah Afobunor
Feven Tadessa Alemu
Otgonjargal Altangerel
Fabliha A. Anam
Netra Anand

Up Next: Graduate School, Public Health

Nicholas W. Arehart

Up Next: Marketing Operations Analyst, Integral Ad Science in New York City

Greti Barokas

Up Next: Medical School, Emory University Class of 2023

Caroline Grace Bauchiero

Up Next: Job Offer, Teaching at Stuffield Academy in Suffield, CT

Anna Lena Bell

Up Next: Job Offer, “Box” Implementation Analyst

Kelsey Lauren Berman
Andrew Tuo Bi
Laura Briggs
Chenxi Cai, Ms
Siying Cen, MS
Zachary Yixin Chen
Shuo Cheng
Sanim Alam Choudhury
Frances Nicole Connor
Paul Frank D’Cunha
Yitao Dai

Up Next: Graduate School, PhD in Pharmacognosy

Christopher Elias Dalloul
Giselle De La Torre

Up Next: Post Baccalaureate Program

Luke Alexander del Balzo
Dian Ding

Up Next: Graduate School, Harvard University, PhD in Chemistry

Corey Eisner
Elizabeth Anne Ejzak
Matthew Paul Epplin, PhD

Up Next: Postdoc, Stanford University

Birk Kenney Evavold
Maxine Dora Faass

Up Next: Graduate School, Northwestern University’s McCormick School of Engineering

Qiyuan Fan
Benjamin MacEwen Fontaine, PhD
Helen Catherine Garby
Julia Lane Gensheimer

Up Next: Medical Scientist Training Program to earn MD/PhD

Ian Allen George

Up Next: Medical School, Duke University School of Medicine

Angel Gonzalez-Valero

Up Next: Graduate School, University of California, Berkeley, PhD in Chemistry

Alexander Ben Grayson
Paul David Greenstein
Ziwei Guo, PhD

Up Next: Pursuing a career in industry

Jennifer Sussette Gutierrez
Garrett Halstein
Talin Handa
Benjamin Heifetz
Caroline Grace Henry
Christopher Hernandez
Lana Lee Herrmann

Up Next: Teaching English in Thailand, Princeton in Asia

Cole Alexander Holan

Up Next: Medical School

Derek Xin Hu
Hyun Hwang
Sabrina Kate Ibabao

Up Next: Dental School

Shivam B Jariwala
Ban-Seok “Samuel” Jeong, PhD

Up Next: Post-doc, Emory University, Dyer Lab

Brittany Symone Jones
Kelly Marie Jones

Up Next: Dental School, University of Connecticut School of Dental Medicine

Malichai E Jordan
Samika Shashank Joshi
Amelia Jane Joyce
Augustine Kang
Colleen Elizabeth Keohane, PhD

Up Next: Scientist, Janssen US

Ryann Khalil
Justin Leal
Eunice Katherine Lee
Noel Xiang’ An Li, PhD

Up Next: Pursuing a Career in Industry

Qiuyang Li, PhD

Up Next: Postdoc

Patricia Chi Lin

Up Next: Graduate School, UC Irvine, PhD in Chemistry

Zhiyin Lu
Shirley Ma
Haleigh Rene Machost
Pranay Reddy Manda
Sheena Mathai
Carmen Metzler

Up Next: Graduate School, University of Puerto Rico, PhD in Chemistry

Jaecheol Min
Taiki Larry Mochizuki
Alexandra Frances Nazzari

Up Next: Job Offer, NIH Post-Bac Position in Vaccinology Lab

Mathew Sebastian Padanilam

Up Next: Medical School, Indiana University

Hyunmin Park, PhD

Up Next: Working for LG Chem, South Korea

Lara Anne Patel, PhD

Up Next: Writing

Jessica Renee Petree, PhD

Up Next: Staff scientist jointly between Khalid Salaita and Cherry Wongtrakool’s labs

Tyler Tri-Thanh Pham
Akshay Krishna Raghuram
Rachel Aryn Reese
Jonathan Thomas Regenold
Alexa Patricia Rendon
Jin Hyeong Rim
Shannon Rivera, PhD

Up Next: Pursuing a Career in Industry

Claire Roesler
Sean Edward Rossiter, MS
Pratik Kumar Rout

Up Next: Clinical Volunteer, Applying to Medical School for 2020

Brian Douglas Savino
Jeffrey Blair Schriber, PhD
Albert Seoh
Faraz Sewani
Emily Ann Silverman

Up Next: Clinical Research Assistant, Brigham and Women’s Hospital Department of Infectious Disease

Rachel Marie Slaugenhaupt
Nandar Soe
Sreesh Sridhar
Kevin Paul Sullivan, PhD
Cory Sylber

Up Next: Research Assistant, Veterans Affairs Hospital

Shannon Thomas
Christina Tian
Gavin Touponse
Niyati Upadhyay
Robert Alexander VanGundy, PhD
Morgan Bair Vaughn, PhD

Up Next: Pursuing Career in Science Communication

Ken Wakabayashi
Dazhi Wang
Jingxi Wang
Minglun Wang
Yijun Wang
Marshall Julian Weber
Emily Elizabeth Weeden
Brett Stephen Weingart
Yuming Wen
Daniel Joon Won

Up Next: Job Offer, ORISE CDC Fellowship, Applying to Dental School

Jung Hyun Won
Yixin Xu

Up Next: Graduate School, University of Kentucky, PhD in Pharmaceutical Sciences

Eric Boyang Yu

Up Next: Medical School, After Gap Year

Ashley Zachmann

Up Next: Graduate School, UNC Chapel Hill, PhD in Chemistry

Avery Michelle Zearfoss
Alexander De-Xiang Zhang
Tianyuan “Sam” Zhang, PhD
Zhechen Zhang
Bethany Marie Ziemer
Samuel Zinga

 

May Research Round-Up

Congratulations to our amazing research teams here in the Department of Chemistry for their publications this month!

Blakey Group

Burman, J., Harris, R., Farr, C., Bacsa, J., & Blakey, S. B. (2019). Rh (III) and Ir (III) Cp* Complexes Provide Complementary Regioselectivity Profiles in Intermolecular Allylic CH Amidation ReactionsACS Catalysis.

Davies Group

Davies, H. M., & Liao, K. (2019). Dirhodium tetracarboxylates as catalysts for selective intermolecular C–H functionalizationNature Reviews Chemistry, 1.

Heaven Group

Schmitz, J. R., Kaledin, L. A., & Heaven, M. C. (2019). Laser induced fluorescence spectroscopy of jet-cooled ThOJournal of Molecular Spectroscopy.

Hill Group

Wang, X., Tao, M., Li, Y., Zhang, X., Li, Z., & Hill, C. L. (2019). A Polyoxometalate‐Based Microfluidic Device for Liquid Phase Oxidation of GlycerolChemSusChem.

Ke Group

Zhang, Y., Pan, V., Li, X., Yang, X., Li, H., Wang, P., & Ke, Y. (2019). Dynamic DNA StructuresSmall, 1900228.

Zhang, Y., Peng, R., Xu, F., & Ke, Y. (2019). Hierarchical Self-Assembly of Cholesterol-DNA NanorodsBioconjugate chemistry.

Lian Group

Ge, A., Rudshteyn, B., Videla, P. E., Miller, C. J., Kubiak, C. P., Batista, V. S., & Lian, T. (2019). Heterogenized Molecular Catalysts: Vibrational Sum-Frequency Spectroscopic, Electrochemical, and Theoretical InvestigationsAccounts of chemical research.

Salaita Group

Ma, V. P. Y., & Salaita, K. (2019). DNA Nanotechnology as an Emerging Tool to Study Mechanotransduction in Living SystemsSmall, 1900961.

Dr. Joel Bowman Takes Sabbatical in Germany with Alexander von Humboldt Research Award

Dr. Joel Bowman, Professor of Theoretical Chemistry here at Emory University, is no stranger to the international scientific arena. While he is a fellow of the American Physical Society and of the American Association for the Advancement of Science, his academic success spans far beyond our national borders. Dr. Bowman also serves as a member of the International Academy of Quantum Molecular Sciences and, most recently, received the international Alexander von Humboldt Research Award in recognition of his lifetime achievements and potential future discoveries. This award, given by the Alexander von Humboldt Foundation in Germany, seeks to foster international scientific collaborations by inviting award recipients to carry out research projects alongside their German colleagues.

This Spring, Dr. Bowman used his award to work at the Max Planck Institute for Biophysical Chemistry in collaboration with professor Alec Wodtke of the University of Goettingen. Before arriving in Goettingen, Dr. Bowman also took the opportunity to travel to Cambridge University where he caught up with colleagues and further strengthened his international collaborations. His research interests involve theoretical and computational techniques to explore chemical reactions and molecular vibrational dynamics. Specifically, Dr. Bowman is interested in understanding the intricacies of the hydrated proton, a seemingly simple player in acid/base chemistry whose true nature is still widely misunderstood.

During his travels, he visited several labs in Germany that share this interest, working on chemical reaction dynamics. In addition, while there was certainly plenty to learn during his trip, Dr. Bowman didn’t miss the opportunity to teach as well. He helped to organize a workshop titled “Developing High-Dimensional Potential Energy Surfaces- From the Gas Phase to Materials”. The workshop was centered around machine learning, a topic which has recently gained attention across several scientific disciplines. By using computer simulations to understand complex mechanisms and quantitatively make predictions, machine learning provides scientists with a powerful tool for addressing otherwise inaccessible inquiries.

The far-reaching scope of machine learning mirrors the breadth of Dr. Bowman’s travels and collaborations. Although he has returned from his sabbatical, Dr. Bowman already plans to revisit Germany in the near future. He says that Germany has “tremendous scientific energy” and is excited to continue collaborating with colleagues across the globe. Of course, during his travels, he will continue to take advantage of the high density of science in Europe. With planes, trains, (and bikes!), he can reach out to colleagues across the entire continent in a very unique and powerful way.

Finally, Dr. Bowman wants to encourage other scientists to reach out for collaborations across the world. He emphasized the value of international collaborations, noting how they can completely transform ideas and enhance the quality of science. “If machine learning is able to take lots of data across boundaries,” says Dr. Bowman, “well then so is science.”

April Research Round-Up

Congratulations to our amazing research teams here in the Department of Chemistry for their publications this month!

Bowman Group

Qu, C., & Bowman, J. M. (2019). A fragmented, permutationally invariant polynomial approach for potential energy surfaces of large molecules: Application to N-methyl acetamideThe Journal of chemical physics150(14), 141101.

Yang, B., Zhang, P., Qu, C., Stancil, P., Bowman, J., Balakrishnan, N., & Forrey, R. (2019). Full-dimensional quantum rovibrational scattering of SO with H2*Bulletin of the American Physical Society.

Dunham Group

Srinivas, P., Goralski, T. D., Keiler, K. C., & Dunham, C. M. (2019). Alternative mechanisms of ribosome stalling rescue in the gram-negative bacterium Francisella tularensisThe FASEB Journal33(1_supplement), 628-3.

Hoffer, E. D., Maehigashi, T., Fredrick, K., & Dunham, C. M. (2019). Ribosomal am biguity (ram) mutations promote 30S domain closure and thereby increase miscodingThe FASEB Journal33(1_supplement), 628-2.

Dunham, C. M., Hoffer, E. D., Nguyen, H. A., Subramanian, S., Hong, S., & Maehigashi, T. (2019). RNA-mediated Mechanisms of Translation ControlThe FASEB Journal33(1_supplement), 100-1.

Zaldana, K. S., Pavelich, I., Moller, A., & Dunham, C. M. (2019). Dissecting the gene regulation of Proteus vulgaris Rts1 HigB-HigA toxin-antitoxin systemThe FASEB Journal33(1_supplement), 458-20.

Pavelich, I., & Dunham, C. M. (2019). Mechanism and stability of type II bacterial toxin-antitoxin complexes and the role of regulated antitoxin proteolysis that releases toxinThe FASEB Journal33(1_supplement), 463-8.

Nguyen, H. A., & Dunham, C. M. (2019). Importance of the m1G37 modification and 32–38 pairing in tRNAPro (CCG) on decoding and tRNA stabilityThe FASEB Journal33(1_supplement), 630-6.

Dyer Group

Sanchez, M. K., Wu, C. H., Adams, M. W., & Dyer, R. B. (2019). Optimizing electron transfer from CdSe QDs to hydrogenase for photocatalytic H 2 productionChemical Communications.

Deng, H., Dyer, R. B., & Callender, R. (2019). Active Site Glu165 Activation in Triosephosphate Isomerase and its Deprotonation KineticsThe Journal of Physical Chemistry B.

Evangelista Group

Zhang, T., Li, C., & Evangelista, F. A. (2019). Improving the efficiency of the multireference driven similarity renormalization group via sequential transformation, density fitting, and the non-interacting virtual orbital approximationarXiv preprint arXiv:1903.11637.

Li, C., Lindh, R., & Evangelista, F. A. (2019). Dynamically weighted multireference perturbation theory: Combining the advantages of multi-state and state-averaged methodsThe Journal of Chemical Physics150(14), 144107.

Heemstra Group

Lackey, H., Peterson, E. M., Chen, Z., Harris, J. M., & Heemstra, J. M. (2019). Thermostability Trends of TNA: DNA Duplexes Reveal Strong Purine DependenceACS synthetic biology.

Ayele, T., Knutson, S. D., Ellipilli, S., Hwang, H., & Heemstra, J. M. (2019). Fluorogenic Photoaffinity Labeling of Proteins in Living CellsBioconjugate Chemistry.

Heaven Group

Le, A. T., Nakhate, S. G., Nguyen, D. T., Steimle, T. C., & Heaven, M. C. (2019). Characterization of gas-phase thorium nitride. The Journal of chemical physics150(14), 144304.

Hill Group

Tao, M., Li, Y., Geletii, Y. V., Hill, C. L., & Wang, X. (2019). Aerobic oxidation of glycerol catalyzed by M salts of PMo12O403-(M= K+, Zn2+, Cu2+, Al3+, Cr3+, Fe3+)Applied Catalysis A: General.

Tian, Y., Plonka, A. M., Ebrahim, A. M., Palomino, R. M., Senanayake, S. D., Balboa, A., … & Mitchell, M. B. (2019). A Correlated Multimodal Approach Reveals Key Details of Nerve-Agent Decomposition by Single Site Zr-Based Polyoxometalates. The journal of physical chemistry letters.

Ke Group

Wang, W., Chen, S., An, B., Huang, K., Bai, T., Xu, M., … & Wei, B. (2019). Complex wireframe DNA nanostructures from simple building blocksNature communications10(1), 1067.

Musaev Group

McLarney, B. D., Hanna, S. R., Musaev, D. G., & France, S. (2019). A Predictive Model for the [Rh2 (esp) 2]-catalyzed Intermolecular C (sp3)-H Bond Insertion of β-carbonyl Ester Carbenes: Interplay Between Theory and ExperimentACS Catalysis.

Tian, Y., Plonka, A. M., Ebrahim, A. M., Palomino, R. M., Senanayake, S. D., Balboa, A., … & Mitchell, M. B. (2019). A Correlated Multimodal Approach Reveals Key Details of Nerve-Agent Decomposition by Single Site Zr-Based PolyoxometalatesThe journal of physical chemistry letters.

Wuest Group

Zhao, W., Cross, A. R., Crowe-McAuliffe, C., Weigert-Munoz, A., Csatary, E. E., Solinski, A., … & Wuest, W. (2019). The natural product elegaphenone potentiates antibiotic effects against Pseudomonas aeruginosaAngewandte Chemie.

Cheng, A. V., & Wuest, W. M. (2019). Signed, Sealed, Delivered: Conjugate and Prodrug Strategies as Targeted Delivery Vectors for AntibioticsACS infectious diseases.

Wilt, I. K., Hari, T. P. A., & Wuest, W. M. (2019). Hijacking the Bacterial Circuitry of Biofilm Processes via Chemical” Hot-Wiring”: An Under-explored Avenue for Therapeutic DevelopmentACS infectious diseases.

Congratulations to the 2019 NSF GRFP Awardees and Honorable Mentions!

Congratulations to the 2019 NSF GRFP Awardees and Honorable Mentions!

The Department of Chemistry is so proud of its NSF Graduate Research Fellowship Awardees for 2019! The NSF Graduate Research Fellowship Program provides recognition and support for outstanding graduate students in NSF-supported STEM disciplines. The GRFP selects recipients with great promise to achieve high levels of success in their future academic and professional endeavors.

2019 NSF GRFP Awardees:

Anna Kaplan

Anna earned her Bachelor’s degree from Bowdoin college before coming to Emory University in 2018. During her undergraduate studies, she participated in The Research Experiences for Undergraduates (REU) Program for two different projects. She has since joined the Wuest Lab, where she works on organic synthesis of natural products and analogs thereof to discover new narrow-spectrum antibiotics. She is also involved in various outreach events with PACS and The Association for Women in Science  (AWIS), including the Atlanta Science Festival and the Emory Summer Science Academy.

 

Savannah Post

Savannah joined the Wuest lab in 2018 after earning her undergraduate degree from Berry College. While at Berry, she worked on methods for stereoselective synthesis and the synthesis of Lumacaftor analogues for the treatment of cystic fibrosis. Now, Savannah works on the total synthesis of an antibacterial natural product. Savannah is also actively involved with The Association for Women in Science (AWIS), currently serving as their Treasurer.

 

Daniel Salgueiro

Daniel, who graduated from Emory University in 2018, now attends graduate school at the University of Wisconsin, Madison. He works in the lab of Dr. Dan Weix, where he uses Cross-Electrophile Coupling (XEC) to form sp3-sp3-sp2 C-C bonds. His NSF proposal was on the use of cooperative diaryl ketone/palladium catalysis to use allylic C-H bonds as pronucleophiles for traditional cross-coupling, based on the research he worked on in Blakey Lab during his time at Emory.

 

Ingrid Wilt

Ingrid is a member of the Wuest lab, currently working on total synthesis of a natural product with anti-fungal activity. Before joining the Wuest lab in 2018, Ingrid attended Colorado College where she conducted research under the guidance of Dr. Habiba Vaghoo. In addition to her research, Ingrid serves as the co-speaker chair for The Association for Women in Science (AWIS).

 

2019 NSF GRFP Honorable Mentions:

Rachel Bender

After graduating from Capital University with a B.A. in chemistry and biochemistry and minors in math and biology, Rachel came to Emory University where she is co-advised by Dr. Jen Heemstra and Dr. Khalid Salaita. Her project involves characterizing the biophysical properties of peptide nucleic acids with a goal of developing them into a tool for analyzing cell mechanics. In addition to her research, Rachel volunteers with Science for Georgia and the Atlanta Science Festival and serves as STEM Activity Leader with the Discovery Program Inc. Rachel has also been the recipient of an Emory Graduate Diversity Fellowship.

Aaron Bosse

Aaron joined the Davies Lab in 2017 after earning his bachelor’s degree from College of the Holy Cross. In the Davies Lab, he works on total synthesis of paracyclophane natural products, method development of new diazo precursors for C-H functionalization, and exotic C-H functionalization substrates useful to pharma. He actively works with the CCHF, having helped run their booth at the Atlanta Science Festival for the past two years. Aaron was named the ACS Division of Organic Chemistry Most Outstanding Senior Undergraduate at Holy Cross and he was the recipient of the Quayle New Student Award here at Emory.

Ana Cheng

Ana came to Emory University from New College of Florida. She joined the Wuest lab in January 2018, where she currently works on synthetic retinoids with anti-MRSA activity. In addition to her interests in total synthesis and medicinal chemistry, Ana is a member of The Association for Women in Science (AWIS) Ana is actively involved with Atlanta Roller Derby as both a skater and board member.

Maddie Dekarske

Maddie earned her Bachelor’s degree from Agnes Scott College before coming to Emory, where she now works in the Wuest Lab. She has two projects in the lab: making analogs of nTZDpa, which kills growing and persisitent S. aureus, and investigating the mechanism of action of honokiol derivatives, which kill S. mutans. Maddie has also received a Goldwater Honorable Mention in 2016 and another NSF GRFP Honorable Mention in 2017, she has been inducted into Omicron Delta Kappa and Mortar Board, and she has been recognized in Who’s Who Among Students at American Universities and Colleges.

Atlanta Science Festival: 2019 Recap

Each year, the Emory University Department of Chemistry participates in the Atlanta Science Festival. This year, we hosted the Chemistry Carnival, an event to share about some of the amazing research taking place in our department through carnival games and fun activities. Children enjoyed playing games like Peptide Jenga and Bacterial Telepathy, while also learning about science from our enthusiastic students.

In addition to the Chemistry Carnival, we had several booths at the Piedmont Park Expo. Dr. Doug Mulford and ChEmory hosted “Pink Ping Pong Big Bang” to teach attendees about The Big Bang through a demonstration involving ping pong balls, liquid nitrogen, and boiling water. Another of our booths, “The BIG World of SMALL Bio-Machines”, was well-attended by children who enjoyed games designed to teach about proteins and their diverse functions. We also hosted “Distance Really Matters” and “Catalyst Carnival” with the CCHF.

The event was a blast for all— attendees and volunteers alike. An event like the Atlanta Science Festival is a wonderful opportunity to bring the community together over a love for science, an enthusiasm for learning, and an ever-present curiosity.

A huge “Thank you!” to everyone who helped make the Atlanta Science festival such a successful and fun event! We couldn’t have done it without you!

March Research Round-Up

Congratulations to our amazing research teams here in the Department of Chemistry for their publications this month!

Bowman Group

Nandi, A., Qu, C., & Bowman, J. M. (2019). Using Gradients in Permutationally Invariant Polynomial Potential fitting: A Demonstration for CH4 Using as Few as 100 ConfigurationsJournal of chemical theory and computation.

Davies Group

Davies, H.M.L., Chennamadhavuni, S., Martin, T.J., Childers, S.R. (2019). U.S. Patent Application No. 15 /145,323

Evangelista Group

Li, C., & Evangelista, F. A. (2019). Multireference Theories of Electron Correlation Based on the Driven Similarity Renormalization GroupAnnual review of physical chemistry70.

Hill Group

Kaledin, A. L., Hill, C. L., Lian, T., & Musaev, D. G. (2019). Modulating electronic coupling at the quantum dot/molecule interface by wavefunction engineeringThe Journal of Chemical Physics150(12), 124704.

Lian Group

Li, Q., Liu, Q., Schaller, R. D., & Lian, T. (2019). Reducing Optical Gain Threshold in Two-Dimensional CdSe Nanoplatelets by Giant Oscillator Strength Transition EffectThe journal of physical chemistry letters.

Kaledin, A. L., Hill, C. L., Lian, T., & Musaev, D. G. (2019). Modulating electronic coupling at the quantum dot/molecule interface by wavefunction engineeringThe Journal of Chemical Physics150(12), 124704.

Lynn Group

Taran, O., Patel, V., & Lynn, D. (2019). Small Molecules Reaction Network That Models ROS Dynamic of the RhizosphereChemical Communications.

Musaev Group

Kaledin, A. L., Hill, C. L., Lian, T., & Musaev, D. G. (2019). Modulating electronic coupling at the quantum dot/molecule interface by wavefunction engineeringThe Journal of Chemical Physics150(12), 124704.

Salaita Group

Sylber, C., Petree, J., Baker, N., Salaita, K., & Wongtrakool, C. (2019). 3582 Scavenger Receptor Expression is Differentially Affected by DNAzyme-Gold Nanoparticle ConjugatesJournal of Clinical and Translational Science3(s1), 20-21.

Wuest Group

Scharnow, A. M., Solinski, A. E., & Wuest, W. M. (2019). Targeting S. mutans biofilms: a perspective on preventing dental cariesMedChemComm.

Post, S., Shapiro, J., & Wuest, W. (2019). Connecting iron acquisition and biofilm formation in the ESKAPE pathogens as a strategy for combatting antibiotic resistanceMedChemComm.

February Research Round-Up

Congratulations to our amazing research teams here in the Department of Chemistry for their publications this month!

Conticello Group

Kreutzberger, M. A., Hughes, S., Conticello, V., & Egelman, E. H. (2019). Structural Studies of the T-and RP4-Pili using Cryo-EMBiophysical Journal116(3), 573a.

Dunham Group

Mehrani, A., Hoffer, E. D., Goralski, T. D., Keiler, K. C., Dunham, C. M., & Stagg, S. (2019). Investigating the Structural Mechanism of the Stalled Bacterial Ribosome Bound to a Drug that Targets Trans-TranslationBiophysical Journal116(3), 573a-574a.

Nguyen, H. A., Hoffer, E. D., & Dunham, C. M. (2019). Importance of tRNA anticodon loop modification and a conserved, noncanonical anticodon stem pairing in tRNAProCGG for decodingJournal of Biological Chemistry, jbc-RA119.

Schureck, M. A., Meisner, J., Hoffer, E. D., Wang, D., Onuoha, N., Ei Cho, S., … & Dunham, C. M. (2019). Structural basis of transcriptional regulation by the HigA antitoxinMolecular microbiology.

Heaven Group

Khvatov, N. A., Zagidullin, M. V., Tolstov, G. I., Medvedkov, I. A., Mebel, A. M., Heaven, M. C., & Azyazov, V. N. (2019). Product Channels of the reactions of O2 (b1Σg+)Chemical Physics.

Hill Group

Hill, C., & Sullivan, K. (2019). U.S. Patent Application No. 16/061,327.

Lian Group

Lian, T., Koper, M. T., Reuter, K., & Subotnik, J. E. (2019). Special Topic on Interfacial Electrochemistry and Photo (electro) catalysis.

Musaev Group

Gair, J., Haines, B. E., Filatov, A. S., Musaev, D. G., & Lewis, J. C. (2019). Di-Palladium Complexes are Active Catalysts for Mono-N-Protected Amino Acid Accelerated Enantioselective CH Functionalization.

Salaita Group

Brockman, J. M., & Salaita, K. (2019). Mechanical Proofreading: A General Mechanism to Enhance the Fidelity of Information Transfer Between Cells Phys. 7: 14. doi: 10.3389/fphy.

Blanchard, A., & Salaita, K. (2019). Autochemophoretic DNA Motors Generate 100+ Piconewton ForcesBiophysical Journal116(3), 292a-293a.

Rao, T. C., Ma, V. P. Y., Urner, T. M., Grandhi, S., Salaita, K., & Mattheyses, A. L. (2019). EGFR Activation Enables Increased Integrin Forces and Organization of Mature Focal AdhesionsBiophysical Journal116(3), 413a.

Quach, M. E., Combs, D., Salaita, K., & Li, R. (2019). Force-Induced Unfolding of a Mechanosensory Domain in Platelet Glycoprotein (Gp) Ib-IX under Solution and Adherent ConditionsBiophysical Journal116(3), 376a.

Weinert Group

Cary, S. P., Boon, E. M., Weinert, E., Winger, J. A., & Marletta, M. A. (2019). U.S. Patent Application No. 10/202,428.