The Emory University School of Medicine students have selected abstracts that have been summarized for the Round-Up, and transformed them into infographic masterpieces. Enjoy!
WEEK 6 (APRIL 22)
Kratzel, Annika et al. “Early Release – Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols – Volume 26, Number 7—July 2020 – Emerging Infectious Diseases Journal – CDC.” Accessed April 21, 2020. https://doi.org/10.3201/eid2607.200915.Gudbjartsson, Daniel F. et al. “Spread of SARS-CoV-2 in the Icelandic Population.” New England Journal of Medicine, April 14, 2020. https://doi.org/10.1056/NEJMoa2006100.Goyal, Parag et al. “Clinical Characteristics of Covid-19 in New York City.” New England Journal of Medicine 0, no. 0 (April 17, 2020): null. https://doi.org/10.1056/NEJMc2010419.Herold, Tobias et al. “Level of IL-6 Predicts Respiratory Failure in Hospitalized Symptomatic COVID-19 Patients.” MedRxiv, April 10, 2020, 2020.04.01.20047381. https://doi.org/10.1101/2020.04.01.20047381.Lavezzo, Enrico et al. “Suppression of COVID-19 Outbreak in the Municipality of Vo, Italy.” MedRxiv, April 18, 2020, 2020.04.17.20053157. https://doi.org/10.1101/2020.04.17.20053157Gritti, Giuseppe et al. “Use of Siltuximab in Patients with COVID-19 Pneumonia Requiring Ventilatory Support.” MedRxiv, April 15, 2020, 2020.04.01.20048561. https://doi.org/10.1101/2020.04.01.20048561Li, Wei, Bo Zhang, Jianhua Lu, Shihua Liu, Zhiqiang Chang, Peng Cao, Xinhua Liu, et al. “The Characteristics of Household Transmission of COVID-19.” Clinical Infectious Diseases. Accessed April 22, 2020. https://doi.org/10.1093/cid/ciaa450Rockx, Barry, Thijs Kuiken, Sander Herfst, Theo Bestebroer, Mart M. Lamers, Bas B. Oude Munnink, Dennis de Meulder, et al. “Comparative Pathogenesis of COVID-19, MERS, and SARS in a Nonhuman Primate Model.” Science, April 17, 2020. https://doi.org/10.1126/science.abb7314Lau, Siu-Ying et al. “Attenuated SARS-CoV-2 Variants with Deletions at the S1/S2 Junction.” Emerging Microbes & Infections 0, no. ja (April 17, 2020): 1–15. https://doi.org/10.1080/22221751.2020.1756700
WEEK 5 (APRIL 15)
Garg, Shikha. “Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019 — COVID-NET, 14 States, March 1–30, 2020.” MMWR. Morbidity and Mortality Weekly Report 69 (2020). https://doi.org/10.15585/mmwr.mm6915e3.Pan, An et al. “Association of Public Health Interventions With the Epidemiology of the COVID-19 Outbreak in Wuhan, China.” JAMA, April 10, 2020. https://doi.org/10.1001/jama.2020.6130.Heinzerling, Amy. “Transmission of COVID-19 to Health Care Personnel During Exposures to a Hospitalized Patient — Solano County, California, February 2020.” MMWR. Morbidity and Mortality Weekly Report 69 (2020). https://doi.org/10.15585/mmwr.mm6915e5Kissler, Stephen M., Christine Tedijanto, Edward Goldstein, Yonatan H. Grad, and Marc Lipsitch. “Projecting the Transmission Dynamics of SARS-CoV-2 through the Postpandemic Period.” Science, April 14, 2020. https://doi.org/10.1126/science.abb5793Mao, Ling et al. “Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China.” JAMA Neurology, April 10, 2020. https://doi.org/10.1001/jamaneurol.2020.1127.Thachil, Jecko et al. “ISTH Interim Guidance on Recognition and Management of Coagulopathy in COVID-19.” Journal of Thrombosis and Haemostasis n/a, no. n/a. Accessed April 15, 2020. https://doi.org/10.1111/jth.14810Ji, Dong et al. “Prediction for Progression Risk in Patients with COVID-19 Pneumonia: The CALL Score.” Clinical Infectious Diseases. Accessed April 15, 2020. https://doi.org/10.1093/cid/ciaa414.Wehrhahn, Michael C. et al. “Self-Collection: An Appropriate Alternative during the SARS-CoV-2 Pandemic.” MedRxiv, April 11, 2020, 2020.04.09.20057901. https://doi.org/10.1101/2020.04.09.20057901“Diagnosis of Acute Respiratory Syndrome Coronavirus 2 Infection by Detection of Nucleocapsid Protein | MedRxiv.” Accessed April 15, 2020. https://www.medrxiv.org/content/10.1101/2020.03.07.20032524v2Wölfel, Roman et al. “Virological Assessment of Hospitalized Patients with COVID-2019.” Nature, April 1, 2020, 1–10. https://doi.org/10.1038/s41586-020-2196-xSutton, Desmond, Karin Fuchs, Mary D’Alton, and Dena Goffman. “Universal Screening for SARS-CoV-2 in Women Admitted for Delivery.” New England Journal of Medicine 0, no. 0 (April 13, 2020): null. https://doi.org/10.1056/NEJMc2009316Grein, Jonathan, Norio Ohmagari, Daniel Shin, George Diaz, Erika Asperges, Antonella Castagna, Torsten Feldt, et al. “Compassionate Use of Remdesivir for Patients with Severe Covid-19.” New England Journal of Medicine 0, no. 0 (April 10, 2020): null. https://doi.org/10.1056/NEJMoa2007016.“No Evidence of Clinical Efficacy of Hydroxychloroquine in Patients Hospitalized for COVID-19 Infection with Oxygen Requirement: Results of a Study Using Routinely Collected Data to Emulate a Target Trial | MedRxiv.” Accessed April 15, 2020. https://www.medrxiv.org/content/10.1101/2020.04.10.20060699v1. Preprint.Sheahan, Timothy P. et al. “An Orally Bioavailable Broad-Spectrum Antiviral Inhibits SARS-CoV-2 in Human Airway Epithelial Cell Cultures and Multiple Coronaviruses in Mice.” Science Translational Medicine, April 6, 2020. https://doi.org/10.1126/scitranslmed.abb5883Tagarro A, Epalza C, Santos M, et al. Screening and Severity of Coronavirus Disease 2019 (COVID-19) in Children in Madrid, Spain [published online ahead of print, 2020 Apr 8]. JAMA Pediatr. 2020;e201346. doi:10.1001/jamapediatrics.2020.1346Gao, Yan et al. “Structure of the RNA-Dependent RNA Polymerase from COVID-19 Virus.” Science, April 10, 2020. https://doi.org/10.1126/science.abb7498.Shi, Jianzhong, Zhiyuan Wen, Gongxun Zhong, Huanliang Yang, Chong Wang, Baoying Huang, Renqiang Liu, et al. “Susceptibility of Ferrets, Cats, Dogs, and Other Domesticated Animals to SARS–Coronavirus 2.” Science, April 8, 2020. https://doi.org/10.1126/science.abb7015Wang, Xinling et al. “SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion.” Cellular & Molecular Immunology, April 7, 2020, 1–3. https://doi.org/10.1038/s41423-020-0424-9.Emanuel, Ezekiel J. et al. “Fair Allocation of Scarce Medical Resources in the Time of Covid-19.” New England Journal of Medicine, March 23, 2020. https://doi.org/10.1056/NEJMsb2005114.Gostin, Lawrence O., Eric A. Friedman, and Sarah A. Wetter. “Responding to COVID-19: How to Navigate a Public Health Emergency Legally and Ethically.” Hastings Center Report n/a, no. n/a. Accessed April 15, 2020. https://doi.org/10.1002/hast.1090Lai, Jianbo et al. “Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019.” JAMA Network Open 3, no. 3 (March 2, 2020): e203976–e203976. https://doi.org/10.1001/jamanetworkopen.2020.3976
WEEK 4 (APRIL 8)
Verity, Robert et al. “Estimates of the Severity of Coronavirus Disease 2019: A Model-Based Analysis.” The Lancet Infectious Diseases 0, no. 0 (March 30, 2020). https://doi.org/10.1016/S1473-3099(20)30243-7.Grasselli, Giacomo et al. “Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy.” JAMA, April 6, 2020. https://doi.org/10.1001/jama.2020.5394Wei, Wycliffe E. “Presymptomatic Transmission of SARS-CoV-2 — Singapore, January 23–March 16, 2020.” MMWR. Morbidity and Mortality Weekly Report 69 (2020). https://doi.org/10.15585/mmwr.mm6914e1.Santarpia, Joshua L. et al. “Transmission Potential of SARS-CoV-2 in Viral Shedding Observed at the University of Nebraska Medical Center.” MedRxiv, March 26, 2020, 2020.03.23.20039446. https://doi.org/10.1101/2020.03.23.20039446Luo, Chao et al. “Possible Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Public Bath Center in Huai’an, Jiangsu Province, China.” JAMA Network Open 3, no. 3 (March 2, 2020): e204583–e204583. https://doi.org/10.1001/jamanetworkopen.2020.4583.Lescure, Francois-Xavier et al. “Clinical and Virological Data of the First Cases of COVID-19 in Europe: A Case Series.” The Lancet Infectious Diseases 0, no. 0 (March 27, 2020). https://doi.org/10.1016/S1473-3099(20)30200-0.Hogan, Catherine A. et al. “Sample Pooling as a Strategy to Detect Community Transmission of SARS-CoV-2.” JAMA, April 6, 2020. https://doi.org/10.1001/jama.2020.5445.Rodino, Kyle G. et al. “Evaluation of Saline, Phosphate Buffered Saline and Minimum Essential Medium as Potential Alternatives to Viral Transport Media for SARS-CoV-2 Testing.” Journal of Clinical Microbiology, March 30, 2020, JCM.00590-20, jcm;JCM.00590-20v1. https://doi.org/10.1128/JCM.00590-20Caly, Leon et al. “The FDA-Approved Drug Ivermectin Inhibits the Replication of SARS-CoV-2 in Vitro.” Antiviral Research, April 3, 2020, 104787. https://doi.org/10.1016/j.antiviral.2020.104787.Molina, Jean Michel et al. “No Evidence of Rapid Antiviral Clearance or Clinical Benefit with the Combination of Hydroxychloroquine and Azithromycin in Patients with Severe COVID-19 Infection.” Médecine et Maladies Infectieuses, March 30, 2020. https://doi.org/10.1016/j.medmal.2020.03.006.Kim, Eun et al. “Microneedle Array Delivered Recombinant Coronavirus Vaccines: Immunogenicity and Rapid Translational Development.” EBioMedicine, April 2, 2020, 102743. https://doi.org/10.1016/j.ebiom.2020.102743.Tai, Wanbo et al. “Characterization of the Receptor-Binding Domain (RBD) of 2019 Novel Coronavirus: Implication for Development of RBD Protein as a Viral Attachment Inhibitor and Vaccine.” Cellular & Molecular Immunology, March 19, 2020. https://doi.org/10.1038/s41423-020-0400-4.CDC MMWR. “Coronavirus Disease 2019 in Children — United States, February 12–April 2, 2020.” MMWR. Morbidity and Mortality Weekly Report 69 (2020). https://doi.org/10.15585/mmwr.mm6914e4.“Lessons After the Early Management of the COVID-19 Outbreak in a Pediatric Transplant and HematoOncology Center Embedded within a COVID-19 Dedicated Hospital in Lombardia, Italy. Estote Parati. by Adriana Balduzzi et al. Preprint. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3559560.Davanzo, Riccardo et al. “Breastfeeding and Coronavirus Disease-2019. Ad Interim Indications of the Italian Society of Neonatology Endorsed by the Union of European Neonatal & Perinatal Societies.” Maternal & Child Nutrition n/a, no. n/a (n.d.): e13010. https://doi.org/10.1111/mcn.13010Gao, Ting et al. “Highly Pathogenic Coronavirus N Protein Aggravates Lung Injury by MASP-2-Mediated Complement over-Activation.” MedRxiv, April 7, 2020, 2020.03.29.20041962. https://doi.org/10.1101/2020.03.29.20041962.Mantlo, Emily K. et al. “Potent Antiviral Activities of Type I Interferons to SARS-CoV-2 Infection.” BioRxiv, April 5, 2020, 2020.04.02.022764. https://doi.org/10.1101/2020.04.02.022764.
WEEK 3 (APRIL 1)
“A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing.” Gordon et al. Preprint: https://doi.org/10.1101/2020.03.22.002386“Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19.” Solomon et al. https://DOI.org/10.1056/NEJMsr2005760Kimball, Anne. “Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility — King County, Washington, March 2020.” MMWR. Morbidity and Mortality Weekly Report 69 (2020). https://doi.org/10.15585/mmwr.mm6913e1.Zeng H, Xu C, Fan J, et al. Antibodies in Infants Born to Mothers With COVID-19 Pneumonia. JAMA. Published online March 26, 2020. https://doi.org/10.1001/jama.2020.4861Zeng L, Xia S, Yuan W, et al. Neonatal Early-Onset Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China. JAMA Pediatr. Published online March 26, 2020. https://doi.org/10.1001/jamapediatrics.2020.0878Gudbjartsson, Daniel F. et al. “Early Spread of SARS-Cov-2 in the Icelandic Population.” Preprint. Epidemiology, March 30, 2020. https://doi.org/10.1101/2020.03.26.20044446.Fatima Amanat et al, “A Serological Assay to Detect SARS-CoV-2 Seroconversion in Humans | MedRxiv.” Posted March 18, 2020. https://www.medrxiv.org/content/10.1101/2020.03.17.20037713v1.Bhatraju, Pavan K. et al. “Covid-19 in Critically Ill Patients in the Seattle Region — Case Series.” New England Journal of Medicine 0, no. 0 (March 30, 2020): null. https://doi.org/10.1056/NEJMoa2004500.Shi, Shaobo et al. “Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China.” JAMA Cardiology, March 25, 2020. https://doi.org/10.1001/jamacardio.2020.0950Mehta, Puja et al. “COVID-19: consider cytokine storm syndromes and immunosuppression.” The Lancet, March 16, 2020. https://doi.org/10.1016/S0140-6736(20)30628-0
Frey, Noelle et al. “Cytokine Release Syndrome with Chimeric Antigen Receptor T Cell Therapy.” Biol Blood Marrow Transplantation, December 17, 2018. https://doi.org/10.1016/j.bbmt.2018.12.756 Zhu, Yuanmei, Danwei Yu, Hongxia Yan, Huihui Chong, and Yuxian He. “Design of Potent Membrane Fusion Inhibitors against SARS-CoV-2, an Emerging Coronavirus with High Fusogenic Activity.” BioRxiv, March 28, 2020, 2020.03.26.009233. https://doi.org/10.1101/2020.03.26.009233Wu, Chaomin et al. “Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China.” JAMA Intern Med. March 13, 2020. https://doi.org/10.1001/jamainternmed.2020.0994Danzi, Gian et al. “Acute pulmonary embolism and COVID-19 pneumonia: a random association?” [published online ahead of print, 2020 Mar 30]. Eur Heart J. https://doi.org/10.1093/eurheartj/ehaa254Fauver, Joseph R. et al. “Coast-to-Coast Spread of SARS-CoV-2 in the United States Revealed by Genomic Epidemiology.” MedRxiv, March 26, 2020. https://doi.org/10.1101/2020.03.25.20043828 Wrapp, Daniel et al. “Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.” BioRxiv, March 28, 2020, 2020.03.26.010165. (Preprint) https://doi.org/10.1101/2020.03.26.010165McMichael, Temet M. et al. “Epidemiology of Covid-19 in a Long-Term Care Facility in King County, Washington.” New England Journal of Medicine 0, no. 0 (March 27, 2020): null. https://doi.org/10.1056/NEJMoa2005412Dong L, Tian J, He S, et al. Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn. JAMA. Published online March 26, 2020. https://doi.org/10.1001/jama.2020.4621Environmental contamination of the SARS-CoV-2 in healthcare premises: An urgent call for protection for healthcare workers. (Preprint) https://www.medrxiv.org/content/10.1101/2020.03.11.20034546v1Spellberg, Brad et al. “Community Prevalence of SARS-CoV-2 Among Patients With Influenza-like Illnesses Presenting to a Los Angeles Medical Center in March 2020.” JAMA, March 31, 2020. https://doi.org/10.1001/jama.2020.4958
