167. Diversity Synthesis Using the Complimentary Reactivity of Rhodium(II)- and Palladium(II)-Catalyzed Reactions

Authors: Aiwu Ni , Jessica E. France , and Huw M. L. Davies

J. Org. Chem.,

2006, 71 (15), 5594–5598


Rhodium(II)-catalyzed reactions of aryldiazoacetates can be conducted in the presence of iodide, triflate, organoboron, and organostannane functionality, resulting in the formation of a variety of cyclopropanes or C−H insertion products with high stereoselectivity. The combination of the rhodium(II)-catalyzed reaction with a subsequent palladium(II)-catalyzed Suzuki coupling offers a novel strategy for diversity synthesis.

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