189. Stereoselective construction of nitrile-substituted cyclopropanes

Authors: Justin R. Denton, Kevin Chenga and Huw M. L. Davies

Chem. Commun.,

2008, 1238-1240

013

Nitrile-substituted cyclopropanes are readily synthesized in a stereocontrolled fashion from the intermolecular cyclopropanation between 2-diazo-2-phenylacetonitrile and electron-rich olefins, catalyzed by the chiral dirhodium complex, Rh2(S-PTAD)4.

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