Authors: Brendan T. Parr , Samantha A. Green , and Huw M. L. Davies
J. Am. Chem. Soc.,
2013, 135 (12), 4716–4718
The synthesis of highly functionalized pyrroles has been achieved by reaction of rhodium-stabilized imino-carbenes with furans. The reaction features an initial [3+2] annulation to form bicyclic hemiaminals, followed by ring opening to generate trisubstituted pyrroles.