{"id":919,"date":"2021-02-18T17:27:01","date_gmt":"2021-02-18T22:27:01","guid":{"rendered":"http:\/\/scholarblogs.emory.edu\/davieslab\/?page_id=919"},"modified":"2021-02-21T21:43:46","modified_gmt":"2021-02-22T02:43:46","slug":"novel-methodologies-and-mechanistic-studies","status":"publish","type":"page","link":"https:\/\/scholarblogs.emory.edu\/davieslab\/novel-methodologies-and-mechanistic-studies\/","title":{"rendered":"Novel Methodologies &amp; Mechanistic Studies"},"content":{"rendered":"<h1>Novel Methodologies<\/h1>\n<p><strong>Dirhodium(II) stabilized donor\/acceptor carbenes<\/strong> display an extensive reactivity profile. A major aspect of our research is to develop these <strong>novel transformations<\/strong> and <strong>explore their scope and limitations<\/strong>. In particular, <strong>asymmetric catalysis<\/strong> has provided an efficient means for the <strong>preparation of a<\/strong> <strong>wide range of essentially enantiopure compounds<\/strong>.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-2315 aligncenter\" src=\"https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/metal-carbenoid-ch-funct.png\" alt=\"\" width=\"542\" height=\"287\" srcset=\"https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/metal-carbenoid-ch-funct.png 1046w, https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/metal-carbenoid-ch-funct-300x159.png 300w, https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/metal-carbenoid-ch-funct-1024x542.png 1024w, https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/metal-carbenoid-ch-funct-768x407.png 768w\" sizes=\"auto, (max-width: 542px) 100vw, 542px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2371\" src=\"https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/methods-equiv.png\" alt=\"\" width=\"1200\" height=\"810\" srcset=\"https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/methods-equiv.png 1200w, https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/methods-equiv-300x203.png 300w, https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/methods-equiv-1024x691.png 1024w, https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/methods-equiv-768x518.png 768w\" sizes=\"auto, (max-width: 767px) 89vw, (max-width: 1000px) 54vw, (max-width: 1071px) 543px, 580px\" \/><\/p>\n\n\n<h1>Mechanistic Studies<\/h1>\n<p>As new and exciting reactivity is discovered within the realm of metal-stabilized carbene chemistry a greater understanding is sought. Through a <strong>number of collaborations<\/strong> we are <strong>bringing together both theoretical and experimental approaches<\/strong> to help understand and expand our novel methodologies.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2322\" src=\"https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/cyclohexadiene-mech-1.png\" alt=\"\" width=\"954\" height=\"657\" srcset=\"https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/cyclohexadiene-mech-1.png 954w, https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/cyclohexadiene-mech-1-300x207.png 300w, https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/cyclohexadiene-mech-1-768x529.png 768w\" sizes=\"auto, (max-width: 767px) 89vw, (max-width: 1000px) 54vw, (max-width: 1071px) 543px, 580px\" \/><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2321\" src=\"https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/cyclopentane-mech-1.png\" alt=\"\" width=\"802\" height=\"681\" srcset=\"https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/cyclopentane-mech-1.png 802w, https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/cyclopentane-mech-1-300x255.png 300w, https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/cyclopentane-mech-1-768x652.png 768w\" sizes=\"auto, (max-width: 767px) 89vw, (max-width: 1000px) 54vw, (max-width: 1071px) 543px, 580px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Novel Methodologies Dirhodium(II) stabilized donor\/acceptor carbenes display an extensive reactivity profile. A major aspect of our research is to develop these novel transformations and explore their scope and limitations. In particular, asymmetric catalysis has provided an efficient means for the preparation of a wide range of essentially enantiopure compounds. &nbsp; Mechanistic Studies As new and &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/scholarblogs.emory.edu\/davieslab\/novel-methodologies-and-mechanistic-studies\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Novel Methodologies &amp; Mechanistic Studies&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1442,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-919","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Novel Methodologies &amp; Mechanistic Studies - The Davies Group<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/scholarblogs.emory.edu\/davieslab\/novel-methodologies-and-mechanistic-studies\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Novel Methodologies &amp; Mechanistic Studies - The Davies Group\" \/>\n<meta property=\"og:description\" content=\"Novel Methodologies Dirhodium(II) stabilized donor\/acceptor carbenes display an extensive reactivity profile. A major aspect of our research is to develop these novel transformations and explore their scope and limitations. In particular, asymmetric catalysis has provided an efficient means for the preparation of a wide range of essentially enantiopure compounds. &nbsp; Mechanistic Studies As new and &hellip; Continue reading &quot;Novel Methodologies &amp; Mechanistic Studies&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/scholarblogs.emory.edu\/davieslab\/novel-methodologies-and-mechanistic-studies\/\" \/>\n<meta property=\"og:site_name\" content=\"The Davies Group\" \/>\n<meta property=\"article:modified_time\" content=\"2021-02-22T02:43:46+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/scholarblogs.emory.edu\/davieslab\/files\/2021\/02\/metal-carbenoid-ch-funct.png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/scholarblogs.emory.edu\\\/davieslab\\\/novel-methodologies-and-mechanistic-studies\\\/\",\"url\":\"https:\\\/\\\/scholarblogs.emory.edu\\\/davieslab\\\/novel-methodologies-and-mechanistic-studies\\\/\",\"name\":\"Novel Methodologies &amp; 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