Catharine Anderson


Group Member Since 2019

B.S. Chemistry
Emory University, Anticipated May 2022

Chem Mentor, Fall 2019 – Present

My research has focused on studying the dynamics of the enzyme PKM2, an isoform of pyruvate kinase, which catalyzes the last step of glycolysis. This enzyme is of interest because of its overexpression in cancer cells and possible implication in the Warburg Effect. I am using fluorescence spectroscopy to detect the allosterically-induced conformational change from the active R-state to the inactive T-state of PKM2. Once this fluorescence change is established, it can be used in a kinetics experiment to measure the timescale on which the conformational change occurs.
Outside the lab, I love to play with my dog Charlie, go on runs, listen to music, and bake.