{"id":1216,"date":"2021-04-14T13:08:58","date_gmt":"2021-04-14T17:08:58","guid":{"rendered":"https:\/\/scholarblogs.emory.edu\/dyerlab\/?page_id=1216"},"modified":"2021-09-29T14:21:39","modified_gmt":"2021-09-29T18:21:39","slug":"seth-wiley","status":"publish","type":"page","link":"https:\/\/scholarblogs.emory.edu\/dyerlab\/group\/postdocs\/seth-wiley\/","title":{"rendered":"Seth A. Wiley"},"content":{"rendered":"\n<div class=\"wp-block-image\"><figure class=\"alignright size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scholarblogs.emory.edu\/dyerlab\/files\/2021\/05\/SETH-1.png\" alt=\"\" class=\"wp-image-1296\" width=\"251\" height=\"350\" srcset=\"https:\/\/scholarblogs.emory.edu\/dyerlab\/files\/2021\/05\/SETH-1.png 501w, https:\/\/scholarblogs.emory.edu\/dyerlab\/files\/2021\/05\/SETH-1-215x300.png 215w\" sizes=\"auto, (max-width: 251px) 100vw, 251px\" \/><\/figure><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<p>seth.alexander.wiley@emory.edu<\/p>\n<p>Group Member Since 2020<\/p>\n<p>Ph.D., University of Michigan, 2020<\/p>\n<p style=\"text-align: left\">B.S., University of Kansas, 2014<\/p>\n<p>As a scientist of diverse research experience and training, I am incredibly interested in using multidisciplinary approaches to cohesively understand how complex bioinorganic systems take advantage of chemical, physical, and biological principles to catalyze chemical reactions. I am particularly fascinated in detangling enzymatic mechanisms.<\/p>\n<p>My current work in the Dyer lab is focused on understanding the chemical and physical framework for how [FeFe] hydrogenases rapidly and reversibly convert protons and electrons into hydrogen under mild conditions. A thorough mechanistic understanding of how these efficient biocatalysts function offers a roadmap to build better synthetic catalysts, potentially laying out a future for clean hydrogen fuel generation. To study these quick enzymes, we employ CdSe-based nanocrystalline semiconductors in conjunction with various spectroscopic techniques such as time-resolved infrared spectroscopy, cryogenic infrared spectroscopy, and UV-visible spectroscopy.<\/p>\n<p>I received my Ph.D. in Chemical Biology at the University of Michigan in 2020 researching the underlying reaction mechanism of carbon incorporation by Acetyl-CoA Synthase (ACS) from <em>Moorella thermoacetica<\/em> under the mentorship of Stephen W. Ragsdale. In my time in the Ragsdale lab, I worked extensively with various spectroscopic methods, focusing primarily on electron paramagnetic resonance (EPR), as well as anoxic laboratory techniques and protein purification.<\/p>\n<p>In addition to my laboratory experience, I have been involved in numerous extracurricular endeavors, and I have been a founding member of two distinct scientific outreach groups spanning communication, outreach, advocacy, and policy. I have given numerous public presentations on a plethora of public scientific discussions ranging from environmental contamination by forever chemicals to genetic engineering with CRISPR. In my spare time, I enjoy cooking, baking, rock climbing, and hanging out with my partner, Madeline and my dog, Matterhorn.<\/p>\n<p><u>Thesis Title<\/u>: \u201c<em>Spectroscopic and Enzymatic Investigations into the Organometallic Incorporation of Methyl and Carbonyl Substrates by Acetyl-Coenzyme A Synthase from<\/em> Moorella thermoaceticum\u201d<\/p>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>seth.alexander.wiley@emory.edu Group Member Since 2020 Ph.D., University of Michigan, 2020 B.S., University of Kansas, 2014 As a scientist of diverse research experience and training, I am incredibly interested in using multidisciplinary approaches to cohesively understand how complex bioinorganic systems take advantage of chemical, physical, and biological principles to catalyze chemical reactions. I am particularly fascinated &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/scholarblogs.emory.edu\/dyerlab\/group\/postdocs\/seth-wiley\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Seth A. Wiley&#8221;<\/span><\/a><\/p>\n","protected":false},"author":4543,"featured_media":0,"parent":276,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-1216","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/scholarblogs.emory.edu\/dyerlab\/wp-json\/wp\/v2\/pages\/1216","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/scholarblogs.emory.edu\/dyerlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/scholarblogs.emory.edu\/dyerlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/scholarblogs.emory.edu\/dyerlab\/wp-json\/wp\/v2\/users\/4543"}],"replies":[{"embeddable":true,"href":"https:\/\/scholarblogs.emory.edu\/dyerlab\/wp-json\/wp\/v2\/comments?post=1216"}],"version-history":[{"count":11,"href":"https:\/\/scholarblogs.emory.edu\/dyerlab\/wp-json\/wp\/v2\/pages\/1216\/revisions"}],"predecessor-version":[{"id":1455,"href":"https:\/\/scholarblogs.emory.edu\/dyerlab\/wp-json\/wp\/v2\/pages\/1216\/revisions\/1455"}],"up":[{"embeddable":true,"href":"https:\/\/scholarblogs.emory.edu\/dyerlab\/wp-json\/wp\/v2\/pages\/276"}],"wp:attachment":[{"href":"https:\/\/scholarblogs.emory.edu\/dyerlab\/wp-json\/wp\/v2\/media?parent=1216"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}