Publications
2023
Metabolic Perturbations Associated with an Exposure Mixture of Per-and Polyfluoroalkyl Substances in the Atlanta African American Maternal-Child Cohort.
Liang D, Taibl KR, Dunlop AL, Barr DB, Ryan PB, Everson T, Huels A, Tan Y, Panuwet P, Kannan K, Marsit C, Jones DP, Eick SM.
Assessing Metabolic Differences Associated with Exposure to Polybrominated Biphenyl and Polychlorinated Biphenyls in the Michigan PBB Registry.
Hoffman SS, Liang D, Hood RB, Tan Y, Terrell ML, Marder ME, Barton H, Pearson MA, Walker DI, Barr DB, Jones DP.
Serum and follicular fluid metabolome and markers of ovarian stimulation.
Hood RB, Liang D, Tan Y, Ford JB, Souter I, Chavarro JE, Jones DP, Hauser R, Gaskins AJ.
The impact of heat exposures on biomarkers of AKI and plasma metabolome among agricultural and non-agricultural workers.
Chicas R, Wang Y, Weil EJ, Elon L, Xiuhtecutli N, Houser MC, Jones DP, Sands JM, Hertzberg V, McCauley L, Liang D
Association between a Mixture of Per-and Polyfluoroalkyl Substances (PFAS) and Inflammatory Biomarkers in the Atlanta African American Maternal–Child Cohort.
Tan Y, Taibl KR, Dunlop AL, Barr DB, Panuwet P, Yakimavets V, Kannan K, Corwin EJ, Ryan PB, Eatman JA, Liang D, Eick SM.
Invited Perspective: Application of Nontargeted Analysis in Characterizing the Maternal and Child Exposome.
Liang D, Walker DI
Exposure to phthalate metabolites, bisphenol A, and psychosocial stress mixtures and pregnancy outcomes in the Atlanta African American maternal-child cohort.
Eatman JA*, Dunlop AL, Barr DB, Corwin EJ, Hill CC, Brennan PA, Ryan PB, Panuwet P, Taibl KR, Tan Y, Liang D, Eick SM.
Environmental health perceptions of urban youth from low‐income communities: A qualitative photovoice study and framework.
Sprague NL, Zonnevylle HM, Jackson Hall L, Williams R, Dains H, Liang D, Ekenga CC.
Newborn metabolomic signatures of maternal per-and polyfluoroalkyl substance exposure and reduced length of gestation.
Taibl KR, Dunlop AL, Barr DB, Li YY, Eick SM, Kannan K, Ryan PB, Schroder M, Rushing B, Fennell T, Chang CJ, Tan Y, Marsit CJ, Jones DP, Liang D.
NIEHS Extramural Paper of the Month
A State-of-the-Science Review on High-Resolution Metabolomics Application in Air Pollution Health Research: Current Progress, Analytical Challenges, and Recommendations for Future Direction.
Liang D, Li Z, Vlaanderen J, Tang Z, Jones DP, Vermeulen R, Sarnat JA.
Respiratory Effects of Traffic-Related Air Pollution: A Randomized, Crossover Analysis of Lung Function, Airway Metabolome, and Biomarkers of Airway Injury
Zhu X, Zhang Q, Du X, Jiang Y, Niu Y, Wei Y, Zhang Y, Chillrud SN, Liang D, Li H, Chen R.
Pregnancy-related hemodynamic biomarkers in relation to trimester-specific maternal per-and polyfluoroalkyl substances exposures and adverse birth outcomes.
Taibl KR, Liang D, Dunlop AL, Barr DB, Smith MR, Steenland K, Tan Y, Ryan PB, Panuwet P, Everson T, Marsit CJ, Kannan K, Jones DP, Eick SM.
Prenatal exposure to persistent and non-persistent chemical mixtures and associations with adverse birth outcomes in the Atlanta African American Maternal-Child Cohort.
Eick SM, Tan Y, Taibl KR, Ryan PB, Barr DB, Hüls A, Eatman J, Panuwet P, D’Souza PE, Yakimavets, V, Lee GE, Brennan PA, Corwin EJ, Dunlop AL, Liang D.
Journal of Exposure Science & Environmental Epidemiology 2023
Longitudinal profiles of the fecal metabolome during the first 2 years of life.
Holzhausen EA, Shen N, Chalifour B, Tran V, Li Z, Sarnat JA, Chang HH, Jones DP, Goran MI, Liang D, Alderete TL.
Saliva and Exhaled Breath Condensate Correlate with Serum in 4-12-Year-Olds Exposed to Secondhand Electronic Cigarette Vapors.
Rodriguez J, Liang D, Tchen R, Yang I.
Prenatal exposure to per- and polyfluoroalkyl substances and childhood autism-related outcomes.
Ames JL, Burjak M, Avalos LA, Braun JM, Bulka CM, Croen LA, Dunlop AL, Ferrara A, Fry RC, Hedderson MM, Karagas MR, Liang D, Lin PD, Lyall K, Moore B, Morello-Frosch R, O’Connor TG, Oh J, Padula AM, Woodruff TJ, Zhu Y, Hamra GB.
2022
Detecting Elevated Air Pollution Levels by Monitoring Web Search Queries: Algorithm Development and Validation.
Lin C, Yousefi S, Kahoro E, Karisani P, Liang D, Sarnat J, Agichtein E.
Urinary oxidative stress biomarkers are associated with preterm birth: an ECHO program study.
Eick SM, Geiger SD, Alshawabkeh A, Aung M, Barrett ES, Bush N, Carroll KN, Cordero JF, Goin DE, Ferguson KK, Kahn LG, Liang D, Meeker J, Milne G, Nguyen R, Padula A, Sathyanarayana S, Taibl KR, Schantz S, Woodruff T, Morello-Frosch R.
Postnatal exposure to ambient air pollutants is associated with the composition of the infant gut microbiota at 6-months of age.
Bailey MJ, Holzhausen EA, Morgan ZE, Naik N, Shaffer JP, Liang D, Chang HH, Sarnat J, Sun S, Berger PK, Schmidt KA, Lurmann F, Goran MI, Alderete TL
Per-and polyfluoroalkyl substances and psychosocial stressors have a joint effect on adverse pregnancy outcomes in the Atlanta African American Maternal-Child cohort.
Eick SM, Barr DB, Brennan PA, Taibl KR, Tan Y, Robinson M, Kannan K, Panuwet P, Yakimavets V, Ryan PB, Liang D, Dunlop AL
Using follicular fluid metabolomics to investigate the association between air pollution and oocyte quality
Hwang S, Hood RB, Hauser R, Schwartz J, Laden F, Jones D, Liang D, Gaskins AJ
Characterizing the follicular fluid metabolome: quantifying the correlation across follicles and differences with the serum metabolome
Hood RB, Liang D, Tan Y, Ford J, Souter I, Jones DP, Hauser R, Gaskins AJ.
Use of high-resolution metabolomics to assess the biological perturbations associated with maternal exposure to Bisphenol A and Bisphenol F among pregnant African American women.
Tchen R, Tan Y, Barr DB, Ryan PB, Tran V, Li Z, Hu YJ, Smith AK, Jones DP, Dunlop AL, Liang D.
Metabolome-wide association study of the relationship between chlorpyrifos exposure and first trimester serum metabolite levels in pregnant Thai farmworkers
Liang D, Batross J, Fiedler N, Prapamontol T, Suttiwan P, Panuwet P, Naksen W, Baumert BO, Yakimavets V, Tan Y, D’Souza P
Attenuation of Piwil2 induced by hypoxic post conditioning prevents cerebral ischemic injury by inhibiting CREB2 promoter methylation
Zhan L, Chen M, Pang T, Li X, Long L, Liang D, Peng L, Sun W, Xu E
Air pollution and blood pressure in the elderly: evidence from a panel study in Nanjing, China
Cai Y, Huang HY, Liang D, Li J, Tang Y, Hong HC, Yan Q, Huang HD, Li Z
Metapone: a Bioconductor package for joint pathway testing for untargeted metabolomics data
L Tian, Z Li, G Ma, X Zhang, Z Tang, S Wang, J Kang, D Liang, T Yu
Effect of exposures to mixtures of lead and various metals on hypertension, pre-hypertension, and blood pressure: A cross-sectional study from the China National Human …
Y Qu, Y Lv, S Ji, L Ding, F Zhao, Y Zhu, W Zhang, X Hu, Y Lu, Y Li, X Zhang, M Zhang, Y Yang, C Li, M Zhang, Z Li, C Chen, L Zheng, H Gu, H Zhu, Q Sun, J Cai, S Song, B Ying, S Lin, Z Cao, D Liang, JS Ji, PB Ryan, DB Barr, X Shi
Attenuation of Piwil2 induced by hypoxic postconditioning prevents cerebral ischemic injury by inhibiting CREB2 promoter methylation
L Zhan, M Chen, T Pang, X Li, L Long, D Liang, L Peng, W Sun, E Xu
Evaluation of the Use of Saliva Metabolome as a Surrogate of Blood Metabolome in Assessing Internal Exposures to Traffic-Related Air Pollution.
Z Li, JA Sarnat, KH Liu, RB Hood, CJ Chang, X Hu, V Tran, R Greenwald, HH Chang, A Russell, T Yu, DP Jones, D Liang
Length of PM2.5 exposure and alternations in the serum metabolome among women undergoing infertility treatment.
RB Hood, D Liang, Z Tang, I Kloog, J Schwartz, F Laden, D Jones, AJ Gaskins.
The oxidative Potential of Fine Particulate Matter and Biological Perturbations in Human Plasma and Saliva Metabolome.
Z Tang, JA Sarnat, RJ Weber, AG Russell, X Zhang, Z Li, T Yu, DP Jones, D Liang
2021
Pesticide residue intake from fruits and vegetables and alterations in the serum metabolome of women undergoing infertility treatment.
RB Hood, D Liang, YH Chiu, H Sandoval-Insausti, JE Chavarro, D Jones, R Hauser, AJ Gaskins
Long-term exposure to low-level NO 2 and mortality among the elderly population in the southeastern United States.
Y Qian, H Li, A Rosenberg, Q Li, JA Sarnat, S Papatheodorou, J Schwartz, D Liang, Y Liu, P Liu, L Shi
Assessment of metabolic perturbations associated with exposure to phthalates among pregnant African American women.
X Zhang, DB Barr, AL Dunlop, P Panuwet, JA Sarnat, GE Lee, Y Tan, EJ Corwin, DP Jones, PB Ryan, D Liang
Per-and polyfluoroalkyl substance (PFAS) exposure, maternal metabolomic perturbation, and fetal growth in African American women: A meet-in-the-middle approach.
CJ Chang, DB Barr, P B Ryan, P Panuwet, MM Smarr, K Liu, K Kannan, V Yakimavets, Y Tan, V Ly, CJ Marsit, DP Jones, EJ Corwin, AL Dunlop, D Liang
High-resolution metabolomics of exposure to tobacco smoke during pregnancy and adverse birth outcomes in the Atlanta African American maternal-child cohort.
Y Tan, DB Barr, PB Ryan, V Fedirko, JA Sarnat, AJ Gaskins, CJ Chang, Z Tang, CJ Marsit, EJ Corwin, DP Jones, AL Dunlop, D Liang
Maternal Plasma Metabolic Profile Demarcates a Role for Neuroinflammation in Non-Typical Development of Children.
RJ Schmidt, D Liang, SA Busgang, P Curtin, C Giulivi
Associations of single and multiple per-and polyfluoroalkyl substance (PFAS) exposure with vitamin D biomarkers in African American women during pregnancy.
CJ Chang, DB Barr, Q Zhang, AL Dunlop, MM Smarr, K Kannan, P Panuwet, V Tangpricha, L Shi, D Liang, EJ Corwin, PB Ryan
Impact of ozone exposure on heart rate variability and stress hormones: a randomized-crossover study.
C Wang, J Lin, Y Niu, W Wang, J Wen, L Lv, C Liu, X Du, Q Zhang, B Chen, J Cai , Z Zhao, D Liang, J Ji, H Chen, R Chen, H Kan
Periconception air pollution, metabolomic biomarkers, and fertility among women undergoing assisted reproduction
AJ Gaskins, Z Tang, RB Hood, J Ford, JD Schwartz, DP Jones, F Laden, D Liang
Reproductive toxicity and metabolic perturbations in male rats exposed to boron
C Wang, Z Kong, L Duan, Deng, Y Chen, S Quan, X Liu, Y Cha, Y Gong, C Wang, Y Shi, W Gu, Y Fu, D Liang, JP Giesy, H Zhang, S Tang
Estimating climate change-related impacts on outdoor air pollution infiltration
D Liang, WC Lee, J Liao, J Lawrence, JM Wolfson, ST Ebelt, CM Kang, P Koutrakis, JA Sarnat
B Hains, R Abi Saab, T Giddings, H Magande, J Grygier, D Liang, Han Gao, JA Sarnat, E Horner
Z Li, D Liang, D Ye, HH Chang, TR Ziegler, DP Jones, ST Ebelt
2020
Dysregulated lipid and fatty acid metabolism link perfluoroalkyl substances exposure and impaired glucose metabolism in young adults
Z Chen, T Yang, DI Walker, DC Thomas, C Qiu, L Chatzi, TL Alderete, JS Kim, DV Conti, CV Breton, D Liang, ER Hauser, DP Jones, FD Gilliland
Urban Air Pollution May Enhance COVID-19 Case-Fatality and Mortality Rates in the United States
D Liang, L Shi, J Zhao, P Liu, JA Sarnat, S Gao, J Schwartz, Y Liu, ST Ebelt, N Scovronick, HH Chang
Photochemical impacts on the toxicity of PM2.5
J Xu, W Hu, D Liang, P Gao
Critical Reviews in Environmental Science and Technology, 2020
Evaluating a multipollutant metric for use in characterizing traffic-related air pollution exposures within near-road environments
JL Moutinho, D Liang, R Golan, ST Ebelt, R Weber, JA Sarnat, AG Russell
Ambient air pollution and sickle cell disease-related emergency department visits in Atlanta, GA
AH Blumberg, ST Ebelt, D Liang, CR Morris, JA Sarnat
Near-road vehicle emissions air quality monitoring for exposure modeling
JL Moutinho, D Liang, R Golan, SE Sarnat, R Weber, JA Sarnat, AG Russell
2019
Metabolome-Wide Association Study of Vanadium Exposure Reveals Exacerbated Fatty Acid Oxidation in Human Plasma and Human Lung Fibroblasts
M Smith, J Fernandes, X Hu, D Liang, M Orr, JA Sarnat, D Jones, YM Go
Shape-dependent toxicity of alumina nanoparticles in rat astrocytes
L Dong, S Tang, F Deng, Y Gong, K Zhao, J Zhou, D Liang, J Fang, M Hecker, JP Giesy, X Bai, H Zhang
Metabolic perturbations following exposures to traffic-related air pollution in a panel of commuters with and without asthma
D Liang, C Ladva, R Golan, T Yu, D Walker, S Sarnat, K Uppal, D Jones, A Russell, J Sarnat
Ambient Air Pollution and Acute Sickle Cell Disease Exacerbation in Atlanta, Ga
J Sarnat, A Blumberg, D Liang
Saliva Metabolome in Detecting Internal Exposure to Traffic Related Air Pollution
D Liang, C Chang, Z Li, B Vu, R Golan, S Sarnat, R Greenwald, D Jones, H Chang, J Sarnat
Perturbations of the arginine metabolome following exposures to traffic-related air pollution in a panel of commuters with and without asthma
D Liang, CN Ladva, R Golan, T Yu, DI Walker, SE Sarnat, R Greenwald, K Uppal, V Tran, DP Jones, AG Russell, JA Sarnat
2018
Use of high-resolution metabolomics for the identification of metabolic signals associated with traffic-related air pollution
D Liang, JL Moutinho, R Golan, T Yu, CN Ladva, M Niedzwiecki, DI Walker, SE Sarnat, H Chang, R Greenwald, DP Jones, AG Russell, JA Sarnat
Hypoxic preconditioning maintains GLT-1 against transient global cerebral ischemia through upregulating Cx43 and inhibiting c-Src
K Li, H Zhou, L Zhan, Z Shi, W Sun, D Liu, L Liu, D Liang, Y Tan, W Xu, E Xu
Particulate metal exposures induce plasma metabolome changes in a commuter panel study
CN Ladva, R Golan, D Liang, R Greenwald, DI Walker, K Uppal, AU Raysoni, V Tran, T Yu, WD Flanders, GW Miller, DP Jones, JA Sarnat
Errors associated with the use of roadside monitoring in the estimation of acute traffic pollutant-related health effects
D Liang, R Golan, JL Moutinho, HH Chang, R Greenwald, SE Sarnat, AG Russell, JA Sarnat
Neuroglobin mediates neuroprotection of hypoxic postconditioning against transient global cerebral ischemia in rats through preserving the activity of
Na+K+ATPases
H Wen, L Liu, L Zhan, D Liang, L Li, D Liu, W Sun, E Xu
Assessment of Fine-Scale Dispersion Modelling for Near-Road Exposure Applications
JL Moutinho, D Liang, J Sarnat, AG Russell
International Technical Meeting on Air Pollution Modelling and its Application, 2018
Acute pulmonary and inflammatory response in young adults following a scripted car commute
R Golan, C Ladva, R Greenwald, JR Krall, AU Raysoni, P Kewada, A Winquist, WD Flanders, D Liang, JA Sarnat
Neuroglobin Mediates Neuroprotection of Hypoxic Postconditioning Against Transient Global Cerebral Ischemia in Rats via Preserving the Activity of
Na+/K+ ATPases
D Liang, J Moutinho, R Golan, T Yu, C Ladva, SE Sarna, H Chang, D Jones, A Russell, JA Sarnat
Developing Multipollutant Exposure Indicators of Traffic Pollution: The Dorm Room Inhalation to Vehicle Emissions (DRIVE) Study
JA Sarnat, RA Ted, D Liang, JL Moutinho, R Golan, RJ Weber, D Gao, SE Sarnat, HH Chang, R Greenwald, T Yu
Dcr1 and Dcr2 Protect Neuron Against Ischemia and Hypoxia Damage via Differential Mechanisms on Ischemia Preconditioning-Induced Neuroprotection
W Xu, W Jin, X Zhang, J Chen, M Liu, S Zhang, C Ren
2012-2017
Metabolomic profiles of plasma, exhaled breath condensate, and saliva are correlated with potential for air toxics detection
CN Ladva, R Golan, R Greenwald, T Yu, SE Sarnat, WD Flanders, K Uppal, DI Walker, V Tran, D Liang, DP Jones, JA Sarnat
Neuroprotection of hypoxic postconditioning against global cerebral ischemia through influencing posttranslational regulations of heat shock protein 27 in
adult rats
L Zhan, L Liu, K Li, B Wu, D Liu, D Liang, H Wen, Y Wang, W Sun, W Liao, E Xu
Autophagosome maturation mediated by Rab7 contributes to neuroprotection of hypoxic preconditioning against global cerebral ischemia in rats
L Zhan, S Chen, K Li, D Liang, X Zhu, L Liu, Z Lu, W Sun, E Xu
Characterization of Traffic Emissions Exposure Metrics in the Dorm Room Inhalation to Vehicle Emissions (DRIVE) Study
JL Moutinho, D Liang, R Weber, J Sarnat, AG Russell
International Technical Meeting on Air Pollution Modelling and its Application, 2016
Metabolic syndrome and the short-term prognosis of acute ischemic stroke: a hospital-based retrospective study
L Liu, L Zhan, Y Wang, C Bai, J Guo, Q Lin, D Liang, E Xu
Hypoxia-inducible factor 1α mediates neuroprotection of hypoxic postconditioning against global cerebral ischemia
T Zhu, L Zhan, D Liang, J Hu, Z Lu, X Zhu, W Sun, L Liu, E Xu
The roles of p38 MAPK/MSK1 signaling pathway in the neuroprotection of hypoxic postconditioning against transient global cerebral ischemia in adult rats
P Zhu, L Zhan, T Zhu, D Liang, J Hu, W Sun, Q Hou, H Zhou, B Wu, Y Wang, E Xu
Activation of Akt/FoxO and inactivation of MEK/ERK pathways contribute to induction of neuroprotection against transient global cerebral ischemia by
delayed hypoxic postconditioning in adult rats
L Zhan, D Li, D Liang, B Wu, P Zhu, Y Wang, W Sun, E Xu