Category: Lit of the Week

Lit of the Week – Sepsis 3.0

Lit of the Week – 3/15/16 Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, Hotchkiss RS, Levy MM, Marshall JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll T, Vincent JL, Angus DC. The Third International Consensus Definitions for Sepsis and Septic …

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Lit of the Week — Airway Assessment Score and Predictors of Difficult BVM

  Lit of the Week – 2/2/16   Reed MJ, Dunn MJ, McKeown DW. Can an airway assessment score predict difficulty at intubation in the emergency department? Emerg Med J. 2005 Feb;22(2):99-102.   Clinical question / background: Can an airway assessment score based on the LEMON method detect difficulty at intubation (Cormack and Lehane Grade …

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Lit of the Week — Antihistamines in Acute Allergic Reaction

Lin RY, Curry A, Pesola GR, Knight RJ, Lee HS, Bakalchuk L, Tenenbaum C, Westfal RE. Improved outcomes in patients with acute allergic syndromes who are treated with combined H1 and H2 antagonists. Ann Emerg Med. 2000 Nov;36(5):462-8. PubMed PMID: 11054200.   Clinical question / background: Does combined H1 and H2 blockade result in improved …

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Lit of the Week – Preoxygenation

Weingart S, et al. “Preoxygenation and prevention of desaturation during emergency airway management.” Ann Emerg Med. 2012;59:165-175. Clinical question / background: ·      Patients requiring emergency airway management are at great risk of hypoxemic hypoxia because of primary lung pathology, high metabolic demands, anemia, insufficient respiratory drive, and inability to protect their airway against aspiration. Tracheal …

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Lit of the Week – Targeted Temperature Management (TTM)

Clinical question / background: In patients with ROSC following cardiac arrest, does cooling patients to 33 degrees Celsius increase the rate of survival after resuscitation compared to cooling to 36 degrees Celsius? Design: Unblinded, parallel-group, randomized, controlled trial 939 participants in 36 European and Australian centers Inclusion criteria: Witnessed arrest Unconscious at presentation Presumed cardiac …

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Lit of the Week – Wells Score

Wells PS, Anderson DR, Rodger M, Stiell I, Dreyer JF, Barnes D, Forgie M, Kovacs G, Ward J, Kovacs MJ. Excluding pulmonary embolism at the bedside without diagnostic imaging: management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and d-dimer. Ann Intern Med. 2001 Jul 17;135(2):98-107. …

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Lit of the Week – Therapeutic Hypothermia

Holzer M, et al. “Mild Therapeutic Hypothermia to Improve the Neurologic Outcome After Cardiac Arrest”. The New England Journal of Medicine. 2002. 346(8):549-556.   Clinical question / background: In patients with ROSC following cardiac arrest due to ventricular fibrillation, does mild systemic hypothermia increase the rate of neurologic recovery after resuscitation?   Design: Unblinded, parallel-group, …

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Lit of the Week – ARDSNet Ventilation

Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med. 2000 May 4;342(18):1301-8.   Clinical question / background: In patients with ARDS, does ventilation with lower tidal volumes versus traditional higher tidal volumes reduce …

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