Category: Toxicology

Lit of the Week — Acute Acetaminophen Toxicity and NAC

Lit of the Week – 3/29/16 Rumack BH, Peterson RC, Koch GG, Amara IA. Acetaminophen overdose. 662 cases with evaluation of oral acetylcysteine treatment. Arch Intern Med. 1981 Feb 23;141(3 Spec No):380-5. PubMed PMID: 7469629.   http://www.ncbi.nlm.nih.gov/pubmed/7469629   Clinical question / background: Does N-acetylcysteine prevent or moderate hepatotoxicity secondary to acute acetaminophen overdose?   Design: …

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