![\"katia_koelle\"](\"https:\/\/scholarblogs.emory.edu\/koellelab\/files\/2018\/08\/katia_koelle.jpg\")
<\/p>\n<\/p>\n
Professor Katia Koelle, PI<\/span><\/strong><\/p>\n Katia is interested in the population dynamics and evolutionary dynamics of infectious diseases. Her research focuses on using modeling approaches to shed light on the drivers of evolutionary change in endemically circulating viral populations, most notably SARS-CoV-2, influenza viruses, and noroviruses. Her work includes both model development and interfacing models with data. She is interested in viral dynamics at multiple scales, including at the epidemiological level, at the transmission pair level, and at the within-host level.<\/span><\/p>\n CV, Google Scholar<\/a><\/span><\/p>\n Email: katia.koelle[at]emory[dot]edu<\/span> Amber Coats (2020-present; Microbiology and Molecular Genetics Ph.D. student)<\/strong><\/p>\n Amber is interested in how viruses evolve in response to selective pressures put in place by to the immune system. Her dissertation work focuses on the role that epistasis plays in viral evolution as well as the role that prolonged infections may or may not play in driving population-level viral evolution. Her studies incorporate approaches such as phylogenetic analyses and mathematical modeling. She was a trainee in the Infectious Disease Across Scales Training Program at Emory University, and part of her dissertation work incorporates linking infectious disease evolution between within-host and between-host scales.<\/p>\n Email: amber.nicole.coats[at]emory[dot]edu<\/span> Yeongseon Park (2019-present;\u00a0 Population Biology, Ecology, and Evolution Ph.D. student)<\/strong> Yeongseon is interested in using genome sequences to understand the population and evolutionary dynamics of viral infectious diseases. She is especially interested in how complex population dynamics of viruses causing infectious disease shape the genetic variation of the virus population and how can we use that to infer transmission dynamics. She is currently working on the development of inference approaches that use the temporal pattern of genetic diversity to estimate epidemiological parameters. She is further interested in how epidemiological model misspecification and non-random sampling impact phylodynamic inference of reproduction rates and ways to address or identify these biases.<\/p>\n GitHub<\/a>\u00a0<\/p>\n Google scholar<\/a>\u00a0<\/p>\n Twitter<\/a>\u00a0<\/p>\n Email: yeongseon.park[at]emory[dot]edu Ananya Saha (2022-present; Population Biology, Ecology, and Evolution Ph.D. student)<\/strong><\/p>\n Ananya is interested in studying viral dynamics and evolution across scales in the context of host immunity, including innate and adaptive (humoral and cellular) immunity. Understanding how immunity acts on viral replication and infection at different scales (within host vs between host) has implications in designing better therapeutic and public health strategies. She is enthusiastic about applying ideas from population genetics, evolutionary biology, and immunology together to gain insights into these topics. She has been working on characterizing antibody dynamics within recently infected or vaccinated individuals as well as analyses that quantify the role of T-cell immunity in impacting the susceptibility or infectivity of individuals. She is jointly advised by Rustom Antia.<\/p>\n Email: ananya.saha[at]emory[dot]edu Elizabeth Somsen (2023-present; Population Biology, Ecology, and Evolution Ph.D. student)<\/strong><\/p>\n Elizabeth is interested in the evolution of viruses and the dynamics of viral pandemics. Her research focuses on developing mathematical and evolutionary models to inform influenza virus pandemic risk assessments. She is especially interested in integrating experimental data with quantitative methods. Currently, she is working on a project that extends within-host viral titer data and mathematical models to estimate epidemiological parameters at the population level. She is supported by a NIH F31 and the Emory IDASTP T32.<\/p>\n Github<\/a>\u00a0<\/p>\n Twitter<\/a><\/p>\n Email: esomsen[at]emory[dot]edu<\/p>\n Office: O. Wayne Rollins Research Center, Rm 1161<\/p>\n Mona Chen (2024\u2013present; Masters in Public Health)<\/strong><\/p>\n Mona is currently completing a Masters in Public Health (Biostats) at the Rollins School of Public Health at Emory. She is interested in developing statistical methods that use deep-sequenced wastewater samples to gain insight into the spatiotemporal dynamics of viral diseases.<\/p>\n Email:\u00a0menghui.chen[at]emory[dot]edu<\/p>\n Fiona Xiao (2024\u2013present; Undergraduate Student)<\/strong><\/p>\n Fiona is originally from Beijing, China, and is currently completing a Bachelor of Science in Quantitative Sciences and Biology at Emory University, with an expected graduation in 2025. She is passionate about infectious disease modeling and evolutionary biology. Fiona is currently working on modeling the effective reproduction number of COVID-19 through wastewater surveillance data.<\/p>\n Email:\u00a0fiona.xiao[at]emory[dot]edu<\/p>\n Lab Pets<\/strong><\/span><\/p>\n Oliver Coats – public relations<\/em><\/p>\n Frances and Felix Koelle<\/em><\/p>\n Former group members<\/strong><\/span><\/p>\n Post-doctoral researchers:<\/em><\/span><\/p>\n Dave VanInsberghe<\/strong> (2020-2022): As a joint post-doc between the Koelle lab and the Lowen lab<\/a>, Dave worked on identifying SARS-CoV-2 recombinant genomes and analyzing an influenza outbreak in pigs at a county fair. Dave now holds a research scientist position in the Lowen Lab<\/a>.<\/p>\n Lisa Bono<\/strong> (2021-2022): As a joint post-doc between the Koelle lab and the Lowen lab<\/a>, Lisa worked on developing models that consider the consequences of cellular coinfection and viral public goods on viral evolution, and interfacing these models with experimental data that quantify the extent to which viruses share public goods. Lisa now holds an Assistant Professor position at Texas Tech University. Google Scholar<\/a><\/p>\n Molly Gallagher<\/strong> (2017-2021): Molly is currently a Computational Epidemiologist at the Johns Hopkins University Applied Physics Laboratory.\u00a0<\/span><\/p>\n Jeremy Harris<\/strong> (2017-2020): Jeremy is currently a post-doc in Joshua Weitz’s group at Georgia Tech.<\/span><\/p>\n Jayna Raghwani<\/a> (2012-2013): Jayna is currently a post-doc in Oli Pybus’s group at Oxford University.<\/span><\/p>\n Oliver Ratmann<\/a> (2009-2012): Olli is currently a Lecturer in Statistics at Imperial College London<\/span><\/p>\n Virginia Pasour<\/a> (2008-2009): Virginia is currently a Program Officer at the Army Research Office (ARO), in the area of biomathematics.<\/span><\/p>\n Graduate students:<\/em><\/span><\/p>\n Mike Martin <\/strong>(2018-2022;\u00a0 Ph.D. in Population Biology, Ecology, and Evolution). In the Koelle lab, Mike used sequence analyses to between understand how viral pathogens evolve within infected hosts, between hosts, and at the population level. While his thesis work was going to focus entirely on influenza virus evolution, most of it ended up being on SARS-CoV-2. In 2022, he joined Kate Grabowski’s research group at Johns Hopkins as a post-doctoral researcher. Google Scholar <\/a>Twitter <\/a>GitHub<\/a><\/p>\n Brent Allman<\/strong> (2016-2o22; Ph.D. in Population Biology, Ecology, and Evolution). In the Koelle lab, Brent used modeling and phylogenetic approaches to better understand the impact that cellular coinfection had on viral evolution and to dissect the role of reservoirs in viral infections. In 2022, he joined Claus Wilke’s lab at UT Austin as a post-doctoral researcher. Google Scholar<\/a><\/p>\n Diana Vera Cruz<\/strong> (2015-2020): Ph.D. in Computational Biology and Bioinformatics. Diana studied viral evolution across scales and how it is impacted by immune selection. In 2020, she joined Sarah Cobey’s group at the University of Chicago as a Research Scientist.<\/span><\/p>\n Ellie Mainou (2018-2019)<\/a>: M.S. in Population Biology, Ecology and Evolution. Ellie’s research focused on the effect of disease control measures in the spread of viral infectious diseases and how such measures may inadvertently impose selection pressure on the pathogens. Her masters thesis involved mathematical modeling to assess how imperfect vaccination may impact dengue virulence evolution. In 2019, she is currently a PhD student in Biology at Penn State working with Jessica M. Conway.<\/span><\/p>\n Ashley Sobel Leonard<\/a> (2012-2016): Ph.D. in Biology (along with an MD from Duke Medical School). Ashley’s research interests focused on the within- and between-host dynamics of influenza. Her thesis included the development and application of a statistical method to infer transmission bottleneck sizes between donor and recipient hosts and statistical analyses of influenza virus sequence data from a human challenge study to examine the speed of viral evolution within challenged hosts and to ascertain the degree of genetic linkage across the flu genome. In 2018, she moved to Seattle, where she is doing her residency while also doing research in Jesse Bloom’s group at the FHCRC.<\/span><\/p>\n Rotem Ben-Shachar<\/a> (2011-2016): Ph.D. in Computational Biology and Bioinformatics. Rotem’s research interests focused on the within-host dynamics of dengue virus. Her thesis included the development of minimal within-host dengue models that were able to reproduce key features of the infection and testing different immunological hypotheses of dengue virus infections by confronting these models with viral load data. She further worked on examining transmission-clearance trade-offs in dengue virus and the effects these trade-offs have on dengue virulence evolution in different epidemiological contexts. After completing a post-doc with Eva Harris and Mike Boots at Berkeley, Rotem joined the Bay Area company Counsyl as a Computational Scientist.<\/span><\/p>\n Stacy Scholle (2010 – 2016): PhD student in Biology. Stacy’s research interests focused on the evolutionary dynamics of hepatitis C virus within chronically infected individuals.<\/span><\/p>\n Chris Castorena (2009 -2013): M.S. in Computational Biology and Bioinformatics. Chris’s research interested focused on the effect of vaccination on the age distribution of disease cases, with a focus on dengue virus. He finished with a Masters and has gone on to work in the private sector.<\/span><\/p>\n David Rasmussen<\/a> (2008 – 2014): Ph.D. in Biology. After doing a post-doc with Tanja Stadler in Basel\/ETH Zurich, David joined NC State University as an Assistant Professor in the Department of Entomology and Plant Pathology.<\/span><\/p>\n Mimi Lin (2007 – 2010): M.S. in Biology. Mimi now works for the Environmental Protection Agency in Research Triangle Park, NC<\/span><\/p>\n Hsiang-Yu (Sean) Yuan<\/a> (2007 – 2013): Ph.D. in Computational Biology and Bioinformatics. After completing a post-doc with Steven Riley at Imperial College London, Sean joined the City University of Hong Kong as as Assistant Professor in Department of Biomedical Sciences.<\/span><\/p>\n Shishi Luo<\/a> (2007-2013): Ph.D. in Mathematics, with honorary membership in the Koelle research group. After completing a post-doc with Alan Perelson at LANL and a second post-doc with Yun Song at Berkeley, Shishi joined the Bay Area company Helix as a Senior Bioinformatics Scientist.<\/span><\/p>\n Associates in research:<\/em><\/span><\/p>\n Olivia Yvellez, Associate in Research, 2016-2017. Olivia\u2019s research focused on the effect of spatial expansions on rapidly evolving viruses, most notably rabies<\/span> Nicole Nova<\/a>, Associate in Research, 2015-2016. Nicole’s research focused on the evolutionary dynamics of antibodies within virus infected hosts. She is currently a PhD student in Biology at Stanford, working with Erin Mordecai.<\/span><\/p>\n Interns:<\/em><\/span><\/p>\n Baptiste Elie, Intern, 2018-2019. \u00a0Baptiste’s interniship was part of his masters studies at ENS Paris-Saclay. His research focused on influenza spatial dynamics and its impact in fitness variation at within-host and population level using a combination of phylogenetics, simulations and experimentation (in collaboration with Anice Lowen’s lab). He is currently doing his masters<\/span><\/p>\n Undergraduates:<\/em><\/span><\/p>\n Several undergrads have done independent studies and\/or have written undergraduate theses in the group. These <\/span>include Jack Lin (2021-2023; now medical student at Vanderbilt), Julie Zhu (2020-2022; now graduate student at Stanford), Max Bagga, Brian Adams, Meredith Kamradt, Rachel Northeim, Priya Khatri, Rachel Willcutts, Alex Dai and Eddie Zhao.<\/span><\/p>\n Visitors:<\/em><\/span><\/p>\n Celeste Donato<\/a> visited in October 2016 from Duke-NUS to work on age distribution patterns of influenza B virus. She is a research fellow in Vijay Dhanasekaran’s group.<\/span><\/p>\n Mark Tanaka<\/a> visited for two weeks in Fall 2014 from the University of New South Wales to work on the dynamics of seasonal influenza viruses over the period of new flu pandemics.<\/span><\/p>\n Rolf Ypma<\/a> visited May 2011 from RIVM, the Netherlands where he was a graduate student with Marijn van Ballegooijen and Jacco Wallinga. He now works at the Netherlands Forensic Institute, The Hague.<\/span><\/p>\n Andrea Richter visited Fall semester 2009 from Barcelona, where she was a graduate student in Xavier Rodo\u2019s IC3 group.<\/span><\/p>\n\n","protected":false},"excerpt":{"rendered":" Professor Katia Koelle, PI Katia is interested in the population dynamics and evolutionary dynamics of infectious diseases. Her research focuses on using modeling approaches to shed light on the drivers of evolutionary change in endemically circulating viral populations, most notably SARS-CoV-2, influenza viruses, and noroviruses. Her work includes both model development and interfacing models with … Continue reading Group members<\/span>
Office: O. Wayne Rollins Research Center, Rm 1015<\/span><\/p>\n![\"\"](\"https:\/\/scholarblogs.emory.edu\/koellelab\/files\/2020\/07\/Amber-Coates-1-447x478.png\")
<\/p>\n
Office: O. Wayne Rollins Research Center, Rm 1161<\/span><\/p>\n![\"\"](\"https:\/\/scholarblogs.emory.edu\/koellelab\/files\/2021\/03\/Yeongseon-Park-1.jpg\")
<\/p>\n
<\/span><\/p>\n
Office: O. Wayne Rollins Research Center, Rm 1161<\/span><\/p>\n![\"\"](\"https:\/\/scholarblogs.emory.edu\/koellelab\/files\/2022\/10\/ananyaSaha-800x478.jpg\")
<\/p>\n
Office: O. Wayne Rollins Research Center, Rm 1161<\/p>\n![\"\"](\"http:\/\/scholarblogs.emory.edu\/koellelab\/files\/2025\/03\/elizabeth_somsen.jpg\")
<\/p>\n![\"\"](\"http:\/\/scholarblogs.emory.edu\/koellelab\/files\/2025\/03\/Xiao_Fiona.jpg\")
<\/p>\n![\"\"](\"https:\/\/scholarblogs.emory.edu\/koellelab\/files\/2022\/10\/oliver-850x478.png\")
<\/p>\n![\"\"](\"http:\/\/scholarblogs.emory.edu\/koellelab\/files\/2025\/03\/frances_felix.jpg\")
<\/p>\n
virus and influenza virus. She started medical school in Fall 2018.<\/span><\/p>\n