Issued US Patents

90. Nucleotide and Nucleoside Therapeutic Compositions and Uses Related Thereto. U.S. Patent 10,149,859.

89. Chemokine CXCR4 Receptor Modulators and Uses Related Thereto. U.S. Patent 10,016,408.

88. 2′ Fluoronucleosides. U.S. Patent 9,861,652.

87. Progesterone Phosphate Analogs and Uses Related Thereto. U.S. Patent 9,802,978.

86. NMDA Receptor Modulators and Uses Related Thereto. U.S. Patent 9,737,522.

85. Chemokine CXCR4 Receptor Modulators and Uses Related Thereto. U.S. Patent 9,545,403.

84. Steriod Analogues for Neuroprotection. U.S. Patent 9,527,881.

83. Tricyclic amino containing compounds for treatment or prevention of symptoms associated with endocrine dysfunction. U.S. Patent 9,205,085.

82. 2′-fluoronucleosides. U.S. Patent 9,180,138.

81. NMDA receptor antagonists for neuroprotection. U.S. Patent 9,079,852.

80. Chemokine CXCR4 receptor modulators and used related thereto. U.S. Patent 8,969,381.

79. Subunit selective NMDA receptor potentiators for the treatment of neurological conditions. U.S. Patent 8,822,462.

78. Process for preparing 5,7 diaminopyrazolo [1,5-A] pyrimidine compounds. U.S. Patent 8,507,673.

77. NMDA receptor antagonists for neuroprotection. U.S. Patent 8,420,680.

76. Triptolide analogs for the treatment of autoimmune and inflammatory disorders. U.S. Patent 8,193,249.

75. 2-fluoronucleosides. U.S. Patent 8,168,583.

74. 2′ and 3′-substituted cyclobutyl nucleoside analogs for the treatment viral infections and abnormal cellular proliferation. U.S. Patent 8,114,994.

73. CXCR4 antagonists for the treatment of medical disorders. U.S. Patent 8,114,884.

72. CXCR4 antagonists including diazine and triazine structures for the treatment of medical disorders. U.S. Patent 8,080,659.

71. Selective inhibitors for cyclin-dependent kinases. U.S. Patent 8,067,424.

70. CXCR4 antagonists for the treatment of HIV infection. U.S. Patent 8,008,312.

69. Curcumin Analogs with Anti-tumor and Anti-angiogenic Properties. U.S. Patent 7,842,705.

68. 2′-fluoronucleosides. U.S. Patent 7,662,938.

67. HIV-1 mutations selected for by .beta.-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine. U.S. Patent 7,635,690.

66. Triptolide analogs for the treatment of autoimmune and inflammatory disorders. U.S. Patent 7,577,139.

65. 2′ and 3′-substituted cyclobutyl nucleoside analogs for the treatment of viral infections and abnormal cellular proliferation. U.S. Patent 7,495,006.

64. Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers. U.S. Patent 7,468,436.

63. 5-Carboxamido or 5-Fluoro-2’,3’-Unsaturated or 3’-Modified-Pyrimidine Nucleosides. U.S. Patent 7,419,966.

62. Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane. U.S. Patent 7,402,588.

61. pH-dependent NMDA receptor antagonists. U.S. Patent 7,375,136.

60. Curcumin analogs with anti-tumor and anti-angiogenic properties. U.S. Patent 7,371,766.

59. 2′-fluoronucleosides. U.S. Patent 7,307,065.

58. Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers. U.S. Patent 7,160,999.

57. HIV-1 mutations selected for by .beta.-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine. U.S. Patent 7,115,584.

56. Therapeutic nucleosides. U.S. Patent 7,053,100.

55. Process of manufacture of 1,3-oxathiolane nucleosides using titanium trichloride mono-isopropoxide. U.S. Patent 6,939,965.

54. 2′-fluoronucleosides. U.S. Patent 6,911,424.

53. Therapeutic nucleosides. U.S. Patent 6,812,233.

52. Triptolide analogs for the treatment of autoimmune and inflammatory disorders. U.S. Patent 6,777,441.

51. Diimino compounds for use as modulators of cell regulation. U.S. Patent 6,750,211.

50. Method of altering sphingolipid metabolism and detecting fumonisin ingestion and contamination. U.S. Patent 6,720,184.

49. Method of Resolution and Antiviral Activity of 1,3-Oxathiolane Nucleoside Enantiomers. U.S. Patent 6,703, 396.

48. 3′,5-difluoro-2′,3′-didehydropyrimidine nucleosides and methods of treatment therewith. U.S. Patent 6,680,303.

47. Curcumin analogs with anti-tumor and anti-angiogenic properties. U.S. Patent 6,664,272.

46. Antiviral Activity and Resolution of 2-Hydroxymethyl-5-(5-Fluorocytosin-1-YL)-1,3. U.S. Patent 6,642,245.

45. Sphingolipid Derivatives and Their Methods of Use. U.S. Patent 6,610,835.

44. Method for the esterification of alcohols and compounds useful therefor as potential anticancer agents. U.S. Patent 6,583,292.

43. Method of manufacture of 1,3-oxathiolane nucleosides. U.S. Patent 6,576,776.

42. Diiminopiperazine derivatives for use in the modification of sphingolipid metabolism and as modulators of cell regulation. U.S. Patent 6,552,025.

41. Method of manufacture of 1,3-oxathiolane nucleosides. U.S. Patent 6,518,425.

40. Compositions and Methods for Targeting Phamaceutically Active Materials to Cells Containing Androgen Receptors. U.S. Patent 6,468,981.

39. Methods for the esterification of alcohols and compounds useful therefor as potential anticancer agents. U.S. Patent 6,399,783.

38. 5-Carboxamido or 5-Fluoro-2’,3’-Unsaturated or 3’-Modified-Pyrimidine Nucleosides. U.S. Patent 6,391,859.

37. 2′-Fluoronucleosides. U.S. Patent 6,348,587.

36. Intermediates in the synthesis of 1,3-oxathiolane nucleoside enantiomers. U.S. Patent 6,346,627.

35. Treatment of HIV by administration of .beta.-D-2′, 3′-didehydro-2′,3′-dideoxy-5-fluorocytidine (D4FC). U.S. Patent 6,232,300.

34. Method of manufacture of 1,3-oxathiolane nucleosides. U.S. Patent 6,215,004.

33. Method and compositions for the synthesis of BCH-189 and related compounds. U.S. Patent 6,153,751.

32. Polycationic oligomers. U.S. Patent 6,153,596.

31. Methods for the esterification of alcohols and compounds useful therefor as potential anticancer agents. U.S. Patent 6,150,537.

30. Method of altering sphingolipid metabolism and detecting fumonisin ingestion and contamination. U.S. Patent 6,127,578.

29. Antiviral activity and resolution of 2-hydroxymethyl-5-(5-flurocytosin-1-yl)-1,3-oxathiolane. U.S. Patent 6,114,343.

28. Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers. U.S. Patent 6,069,252.

27. Diastereoselective synthesis hydroxyethylene dipeptide isosteres. U.S. Patent 5,990,341.

26. Method and compositions for the synthesis of BCH-189 and related compounds. U.S. Patent 5,914,400.

25. Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane. U.S. Patent 5,914,331.

24. [5–Caboxamido or 5–fluoro]–[2′, 3′–unsaturated or 3′–modified]–pyrimidine nucleosides. U.S. Patent 5,905,070.

23. Treatment of Urogenital Cancer with Boron Neutron Capture. U.S. Patent 5,872,107.

22. Method of Resolution and Antiviral Activity of 1.3-Oxathiolane Nucleoside Enantiomers. U.S. Patent 5,892,025.

21. Antiviral 1.3-Dioxolane Nucleoside Analogues. U.S. Patent 5,852,027.

20. Method of resolution of 1,3-oxathiolane nucleoside enantiomers. U.S. Patent 5,827,727.

19. Method for the synthesis, compositions and use of 2′-deoxy-5-fluoro-3′-thiacytidine and related compounds. U.S. Patent 5,814,639.

18. Method of Resolution of 1,3-Oxathiolane Nucleoside Enantiomers. U.S. Patent 5,728,575.

17. Compositions Containing 5-Fluoro-2’,3’-Didehydro-2’,3’-Dideoxycytidine Or A Mon-, Di-, Or Triphosphate Thereof And A Second Antiviral Agent. U.S. Patent 5,703,058.

16. Method for the Synthesis, Composition and Use of 2′-Deoxy-5-Fluoro-3′-Thiacyctidine and Related Compounds. U.S. Patent. 5,700,937.

15. One Vessel Stereoselective Glycosylation of Purines and Pyrimidines. U.S. Patent 5,602,245.

14. Treatment of urogenital cancer with boron neutron capture therapy. U.S. Patent 5,599,796.

13. Diastereoselective synthesis of hydroxyethylene dipeptide isosteres. U.S. Patent 5,587,514.

12. Method and Composition for the Synthesis of BCH-189 and Related Compounds. European Patent 5,539,116.

11. 4-Arylisoindole Analgesics. U.S. Patent 5,508,424.

10. Sensitizing agents for use in boron neutron capture therapy. U.S. Patent 5,462,724.

9. Preparation of 3’-Substituted-2’,3’-Dideoxynucleosides and 2’-Deoxynucleosides from Acyclic, Achiral Precursors. U.S. Patent 5,432,273.

8. Preparation of 3’-Substituted-2’,3’-Dideoxynucleosides and 2’-Deoxynucleosides from Acyclic, Achiral Precursors. U.S. Patent 5,414,078.

7. Novel Sensitizing Agents for Boron Neutron Capture Therapy. U.S. Patent 5,405,598.

6. Methods of Synthesis of 1,3-Dioxolane Nucleosides. U.S. Patent 5,276,151, 1994.

5. Method of Altering Sphingolipid Metabolism and Detecting Fumonisin. U.S. Patent 5,232,837.

4. Methods for the Synthesis, Composition and Use of 2′-Deoxy-5-Fluoro-3′-Thiacytidine and Related Compounds. U.S. Patent 5,210,085.

3. Method and Compositions for the Synthesis of BCH-189 and Related Compounds. U.S. Patent 5,204,466.

2. Method of Preparing Sphingosine Derivatives. U.S. Patent 5,110,987.

1. 2-1,4 Addition Reaction Sequence Leading to Diphenylacetylenes. U.S. Patent 4,772,755.