Federal Funding
1. NIH EB T32 EB025816 Stanley/Ting (MPI) 7/19-6/29 $2M Training in Computational Neural Engineering An innovative training program at Georgia Tech and Emory University to train the next generation of researchers at the intersection of computational neuroscience, data science, and clinical neurophysiology. 2. NIH R01 HD90642-06 Ting/Cope/Sawicki (MPIs)6/21-5/26 $3.5M ($1.5M) Multi-scale models of proprioceptive encoding to reveal mechanisms of impaired sensorimotor control To develop integrated models of muscle spindles proprioceptive afferents and musculotendon dynamics to understand neural contributors to joint hyperresistance disorders across multiple neurological disorders, such as spasticity and hypertonia. Role: PI (25%) 3. NIH R01 AG072756-01 Ting/Borich (MPI) 6/22-3/27 $3.6M ($1.5M) Individual-specific engagement of cortical resources for standing balance control in aging and post-stroke To identify cortical activity signatures of engagement of cortical resources for balance control using EEG during perturbed balance control. Role: Contact PI (30%) 4. NIH R01 3 HD90642-067S1 Ting 9/22-5/23 $200K Biophysical muscle modeling software for enhancing open science To develop state-of-the art software for predicting muscle function to be shared widely with researchers in the musculoskeletal and cardiac research fields. Co-I’s: Campbell, De Groote 5. NSF BII Daley 3/24-2/30 $12 M ($300K) BII: Integrative Movement Sciences Institute (IMSI) A consortium to identify principles of multiscale dynamic muscle function towards an integrative understanding of movement Role: Participating Faculty member 6. NIH R01 HD46922-16 Ting/Borich (MPI) 9/24-8/29 $3.2M Neuromechanical Modeling of Postural Responses: Cortical mechanisms of balance impairments in Parkinson’s disease To identify the cortical correlates of perceptual-cognitive-motor interactions impairing balance control in Parkinson’s disease. (impact score: 20, 4th %-ile) Role: PI (30%) |
Mentored Fellowships
1.NIH F31HD107968 Winner (PI) 2/22-1/25 $150K Identifying individual-specific gait signatures for stroke rehabilitation Role: Sponsor (0%) with co-sponsors Kesar and Berman 2. NIH F32 HD108927 Rosenberg (PI) 6/22-5/25 $180K Modulation of gait dynamics post-stroke Role: Sponsor (0%) with co-sponsors Kesar and Berman 3. ASEE eFellows Jakubowski (PI) 9/22-8/24 $150K Physiologically inspired, machine learning-based exoskeleton controller to prevent falls Role: Sponsor (0%) with co-sponsors Sawicki and Young 4. NIH F31 AG081129 Mason (PI) 2/23-1/26 $200K The effect of aging and cognitive impairment on prefrontal cortical inputs to motor cortical outputs during standing balance control. Role: Sponsor (0%) with co-sponsors Kesar and Borich 5. McCamish Postdoctoral Fellowship Monaghan (PI) 9/24-8/25 $60K Mechanism of perceptual impairments in Parkinson’s disease Role: Sponsor (0%) |
Seed Grants
1. McCamish Blue Sky Grant Ting (PI) 8/23-9/24 $125K Neuromechanical interactions between perceptual, cognitive, and motor deficits underlying balance impairments in Parkinson’s disease 2. Emory I3-SoM Research Award Hackney (PI) 8/23-9/24 $25K Data-driven individual-specific “gait signatures” for diagnosis and rehabilitation of mobility deficits in older adults with cognitive impairments Role: Co-PI |
Prior
Previous Support
| 1. RG-02-0747 Ting (PI) 9/1/03-8/31/06 $279 K total Whitaker Foundation Biomedical Engineering Research Grant Neuromechanical Determinants of Postural Responses To develop experimental and simulation tools to investigate and quantify biomechanical and sensorimotor mechanisms during postural response. Our models will predict the time course of muscle activity during postural responses in humans standing balance. 2.NIH R01 HD46922 Ting (PI) 4/1/04-3/31/09 $1.7 M Neuromechanical Modeling of Postural Responses The goal is to analyze and model musculoskeletal coordination in the cat hindlimb during balance responses in normal and neurologically impaired animals. 3. R01 NS020855 Nichols (PI) 12/2003-11/2008 $1.7M($50K) Spinal Mechanisms Regulating Muscle and Limb Mechanics These animal studies investigate the neurophysiological and musculoskeletal basis of postural responses and will compare responses in an acute preparation to postural responses in awake, behaving animals. Role: Consultant (5%) 4. Seed Grant Shinohara (PI) 9/1/08-8/31/09 $30 K GT/ Emory BME-Neurology Predicting individual’s optimal noise for posture improvement in balance-impaired individuals Role: Co-PI 5. NIH R01 NS053822 Ting (PI) 3/07-2/13 $1.4M Neuromechanical Determinants of Muscle Activity in Human Postural Responses The goal is to experimentally and computationally model spatial and temporal patterns of muscle activity and their functional consequences during human postural control. 6. Seed Grant McKay/Hackney (PI) 4/12-3/13 $35K Emory NIH Udall Parkinson’s Center/ACTSI Mechanisms of balance improvement during Parkinson’s disease rehabilitation To examine basal-ganglia mediated improvements in balance following rehabilitation Role: Co-PI 7. Seed Grant Trumbower/Ting (PIs) 7/12-6/14 $100K Petit Institute for Interdisciplinary Research Acute intermittent hypoxia-induced enhancement of locomotor muscle coordination in persons with incomplete spinal cord injury To quantify deficits in locomotor muscle coordination in persons with spinal cord injury, and improvements following acute intermittent hypoxia treatment. 8. NIH R01 HD46922-06 Ting (PI) 4/09-3/15(NCE to 3/16) $1.7 M Neuromechanical Modeling of Postural Responses The goal is to analyze and model musculoskeletal coordination in the cat hindlimb during balance responses in normal and neurologically impaired animals. 9. GT Neural Engineering Center Seed Grant Ting (PI) 1/15-6/16 $20K Measuring and manipulating cortical brain activity for human balance To measure changes in electroencephalographic (EEG) event related potentials (ERPs) during perturbation to standing balance,and alter them with transcranial magnetic stimulation (TMS). 10. NIH R21 HD075612 Ting (PI) 8/13-5/15 (NCE to 5/17) $450K Mechanisms of improvement in neurorehabilitation of Parkinson’s Disease To investigate improvements in balance following adapted tango rehabilitation are mediated by basal-ganglia versus cerebellar plasticity. 11. NIH R01 HD082174 Trumbower (PI) 9/14-6/17 $2.5M ($100K) Mechanisms of intermittent hypoxia-induced motor recovery in persons with chronic SCI To examine how a novel breathing intervention affect recovery of walking ability and is affected by genetic constraints and competition of cellular pathways of neural plasticity. Role: co-I (5%) to aid in examination of muscle coordination and biomechanics 12. NSF EFRI 1137229 Ting (PI) 10/11-9/15 (NCE to 9/17) $2M total ($1.2 M) EFRI M3C: Partnered Rehabilitative Movement: Cooperative human-robot interaction for motor rehabilitation, learning, and communication To develop novel predictive models for motor cooperation based on haptic interaction that forge new paths toward fully automated robots that can physically to enhance, assist, and improve motor skills in humans with varying motor capabilities. 13. NCSRR Pilot Project Fregly (PI) 1/17-12/17 Computational Design of FastFES Rehabilitation to Improve Post-Stroke Gait Role: Co-I for collection and analysis of data 14. NIH R01 NR016151 Shen (PI) 8/15-8/18 $1.1M ($180K) NRI: Collaborative Research: Quadrupedal Human-Assistive Robotic Platform (Q-HARP) Our role is to measure interaction forces between caregivers frail older adults during assisted walking in order to provide design target for an assistive robot. Role: collaborative PI (6%) 15. GT/GSU Center for Advanced Brain Imaging Ting (PI) 7/1/16-6/31/17 Neuroimaging to predict gait rehabilitation outcomes post-stroke To identify whether brain structure and resting state connectivity predict responders and non-responders to gait rehabilitation. 16. Udall Pilot Grant Ting, Factor (PI) 6/17-11/18 $30K Common neurophysiological markers underlying cognitive and balance deficits in Parkinson’s disease 17. NIH R01 HD46922-S1 Ting (PI) 6/19-5/21 $0.1M Minority supplement to Alejandro Lopez 18. NSF DGE 1545287 Howard (PI) 9/15 – 8/20 $3M total ($50K) NRT:Accessibility, Rehabilitation and Movement Science (ARMS): An Interdisciplinary Traineeship Program in Human-Centered Robotics Role: Co-PI (4%) 19. NIH R01 HD90642 Ting (PI) 9/16-5/21 $1.7M ($700K) Collaborative Research: Multi-scale models of muscle spindles for understanding sensorimotor control To develop muscle model based on cross-bridge, musculotendon, and neuron properties that accounts for behaviorally-relevant history-dependent behaviors of sensory encoding in muscle spindles proprioceptive afferents. Role: PI (20%) 20. NIH R01 HD46922-11 Ting (PI) 9/17-5/22 (NCE to ‘23) $3.6M Neuromechanical Modeling of Postural Responses: Mechanisms of balance impairments in Parkinson’s disease To identify the causal role of abnormal muscle activity associated with Parkinsonian rigidity on postural instability through integrated experiments and simulations of reactive balance. Role: PI (30%) 21. NSF CMMI M3X 1762211 Ting (PI) 6/18-5/23 $900K ($367K) Collaborative Research: Enhanced gait dynamics via physical human-human and human-robot interactions at the hands To generate data-driven, predictive models of human gait that capture the effects of human gait assistance and use these to develop a novel gait assistance robotic platform. Role: PI (10%) |
Previous Mentored Awards
| 1. ACTSI KL2 McKay (PI) 8/14 – 7/16 $150K Mentored Clinical and Translational Research Scholars (MCTRS) Reactive Balance to Identify Disease Phenotypes and Predict Falls in Parkinson’s Disease Role: Mentor (0%) 2. T32 Translational Neurology Allen (PI) 7/14-6/15 $50K Cortical connectivity during functional balance reactions in stroke survivors Role: Mentor (0%) with Kesar 3. NIH F32 NS087775 Allen (PI) 7/15 – 6/17 $115K Muscle coordination changes affecting impaired balance control post-stroke. Role: Mentor (0%) 4. NIH F31 NS093855 Blum (PI) 8/15-8/18 $129K Proprioceptive models for control of movement Role: Mentor (0%) 5. NIH K25 HD086276 McKay (PI) 9/16-8/20 $450K Neural mechanisms of balance deficits, falls, and freezing of gait in Parkinson’s disease Role: Mentor (0%) 6. Banting Postdoctoral Fellowship Horslen (PI) 5/18-4/20 $130K CIHR: Canadian Institutes of Health Research How current movement shapes future sensory feedback: A multiscale investigation of how changing muscle mechanics affects muscle spindle sensory feedback and control of standing balance Role: Mentor (0%) 7. AHA Postdoctoral Fellowship Palmer (PI) 9/18-8/20 $150K Cortical connectivity during functional balance reactions in stroke survivors Role: Co-Mentor (0%) with Borich 8. NIH F32 HD096816 Palmer (PI) 2/19-8/21 $150K Cortical connectivity during functional balance reactions in stroke survivors Role: Co-Mentor (0%) with Borich 9. NIH T32 Translational Neurology Mirdamadi (PI)7/20-6/21 $50K Neural correlates of whole-body motion perception during balance perturbations in stroke survivors and their relationship to balance function Role: Co-sponsor (0%) with sponsor Borich 10. NSF GRFP Winner (PI) 2019-2022 $150K 11. McCamish Postdoctoral Fellowship Beck (PI) 7/21-1/23 $90K Muscle coactivation and balance control in older adults with and without Parkinson’s disease Role: Sponsor (0%) 12. NSF GRFP Boebinger (PI) 2020-2023 $150K Cortical sensorimotor control mechanisms of reactive balance in health and disease 13. NIH F32 HD105458 Mirdamadi (PI) 7/21-6/23 $120K Neural correlates of whole-body motion perception during balance perturbations in stroke survivors and their relationship to balance function Role: Co-sponsor (0%) with sponsor Borich |