{"id":1731,"date":"2024-03-06T04:01:54","date_gmt":"2024-03-06T04:01:54","guid":{"rendered":"https:\/\/scholarblogs.emory.edu\/neuromechanicslab\/?page_id=1731"},"modified":"2024-08-05T13:29:35","modified_gmt":"2024-08-05T13:29:35","slug":"funded-projects-2","status":"publish","type":"page","link":"https:\/\/scholarblogs.emory.edu\/neuromechanicslab\/research\/funded-projects-2\/","title":{"rendered":"Funded Projects"},"content":{"rendered":"\n

Federal Funding<\/h4>\n\n\n\n

1. NIH EB T32\u00a0EB025816\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Stanley\/Ting (MPI)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a07\/19-6\/29\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0$2M
Training in Computational Neural Engineering<\/em><\/strong>
An innovative training program at Georgia Tech and Emory University to train the next generation of researchers at the intersection of computational neuroscience, data science, and clinical neurophysiology.
\u00a0
2. NIH R01\u00a0HD90642-06\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Ting\/Cope\/Sawicki (MPIs)6\/21-5\/26\u00a0\u00a0\u00a0\u00a0\u00a0$3.5M ($1.5M)
Multi-scale models of\u00a0proprioceptive encoding to reveal mechanisms of impaired sensorimotor control<\/em><\/strong>
To develop integrated models of muscle spindles proprioceptive afferents and musculotendon dynamics to understand neural contributors to joint hyperresistance disorders across multiple neurological disorders, such as spasticity and hypertonia.\u00a0
Role:<\/strong>\u00a0PI (25%)
\u00a0
3. NIH\u00a0R01 AG072756-01\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Ting\/Borich (MPI)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a06\/22-3\/27\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0$3.6M ($1.5M)
Individual-specific engagement of cortical resources for standing balance control in aging and post-stroke<\/em><\/strong>
To identify cortical activity signatures of engagement of\u00a0cortical resources<\/em>\u00a0for balance control using EEG during perturbed balance control.
Role:<\/strong>\u00a0Contact PI (30%)
\u00a0
4. NIH R01 3\u00a0HD90642-067S1\u00a0\u00a0\u00a0\u00a0Ting\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a09\/22-5\/23\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0$200K
Biophysical muscle modeling software for enhancing open science<\/em><\/strong>
To\u00a0develop state-of-the art software for predicting muscle function to be shared widely with researchers in the musculoskeletal and cardiac research fields.\u00a0
Co-I\u2019s:<\/strong>\u00a0Campbell, De Groote
\u00a0
5. NSF BII\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Daley\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 3\/24-2\/30\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0$12 M ($300K)
BII: Integrative Movement Sciences Institute (IMSI)<\/em><\/strong>
A consortium to identify principles of multiscale dynamic muscle function towards an integrative understanding of movement
Role:<\/strong>\u00a0Participating Faculty member

6. NIH R01 HD46922-16\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Ting\/Borich (MPI)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a09\/24-8\/29\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0$3.2M
Neuromechanical Modeling of Postural Responses: Cortical mechanisms of balance impairments in Parkinson\u2019s disease<\/em> \u00a0<\/strong>
To identify the cortical correlates of perceptual-cognitive-motor interactions impairing balance control in Parkinson\u2019s disease. (impact score: 20, 4th<\/sup> %-ile)\u00a0
Role:<\/strong> PI (30%)\u00a0<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Mentored Fellowships<\/h4>\n\n\n\n

1.NIH F31HD107968                   Winner (PI)                 2\/22-1\/25                    $150K
Identifying individual-specific gait signatures for stroke rehabilitation<\/em>
Role:<\/strong> Sponsor (0%) with co-sponsors Kesar and Berman
 
2. NIH F32 HD108927                 Rosenberg (PI)            6\/22-5\/25                    $180K
Modulation of gait dynamics post-stroke<\/em>
Role:<\/strong> Sponsor (0%) with co-sponsors Kesar and Berman
 
3. ASEE eFellows                         Jakubowski (PI)          9\/22-8\/24                    $150K
Physiologically inspired, machine learning-based exoskeleton controller to prevent falls
Role:<\/strong> Sponsor (0%) with co-sponsors Sawicki and Young
 
4. NIH F31 AG081129                 Mason (PI)                  2\/23-1\/26                    $200K
The effect of aging and cognitive impairment on prefrontal cortical inputs to motor cortical outputs during standing balance control.<\/em>
Role:<\/strong> Sponsor (0%) with co-sponsors Kesar and Borich
 
5. McCamish Postdoctoral Fellowship Monaghan (PI)   9\/24-8\/25               $60K
Mechanism of perceptual impairments in Parkinson\u2019s disease<\/em>
Role:<\/strong> Sponsor (0%)
<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Seed Grants<\/h4>\n\n\n\n

1. McCamish Blue Sky Grant                   Ting  (PI)        8\/23-9\/24                   $125K
Neuromechanical interactions between perceptual, cognitive, and motor deficits underlying balance impairments in Parkinson\u2019s disease<\/em>
 
2. Emory I3-SoM Research Award          Hackney  (PI)  8\/23-9\/24                   $25K
Data-driven individual-specific \u201cgait signatures\u201d for diagnosis and rehabilitation of mobility deficits in older adults with cognitive impairments <\/em>
Role:<\/strong> Co-PI                              <\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

<\/p>\n\n\n\n

Prior<\/h4>\n\n\n\n
Previous Support<\/summary>\n
1. RG-02-0747 Ting (PI) 9\/1\/03-8\/31\/06 $279 K total 
Whitaker Foundation Biomedical Engineering Research Grant <\/strong>
Neuromechanical Determinants of Postural Responses<\/em> 
To develop experimental and simulation tools to investigate and quantify biomechanical and sensorimotor mechanisms during postural response. Our models will predict the time course of muscle activity during postural responses in humans standing balance. 
 
2.NIH R01 HD46922 Ting (PI) 4\/1\/04-3\/31\/09 $1.7 M  
Neuromechanical Modeling of Postural Responses<\/em>  <\/strong>
The goal is to analyze and model musculoskeletal coordination in the cat hindlimb during balance responses in normal and neurologically impaired animals. 
 
3. R01 NS020855   Nichols (PI) 12\/2003-11\/2008       $1.7M($50K) 
Spinal Mechanisms Regulating Muscle and Limb Mechanics<\/em> <\/strong>
These animal studies investigate the neurophysiological and musculoskeletal basis of postural responses and will compare responses in an acute preparation to postural responses in awake, behaving animals. 
Role: Consultant (5%)<\/em> 
 
4. Seed Grant Shinohara (PI) 9\/1\/08-8\/31\/09 $30 K  
GT\/ Emory BME-Neurology  <\/strong>
Predicting individual\u2019s optimal noise for posture improvement in balance-impaired individuals<\/em> 
Role<\/strong>: Co-PI 
 
5<\/strong>. NIH R01 NS053822 Ting (PI) 3\/07-2\/13 $1.4M  
Neuromechanical Determinants of Muscle Activity in Human Postural Responses <\/em> <\/strong>
The goal is to experimentally and computationally model spatial and temporal patterns of muscle activity and their functional consequences during human postural control.  
 
6. Seed Grant McKay\/Hackney (PI) 4\/12-3\/13 $35K 
Emory NIH Udall Parkinson\u2019s Center\/ACTSI  <\/strong>
Mechanisms of balance improvement during Parkinson\u2019s disease rehabilitation<\/em> 
To examine basal-ganglia mediated improvements in balance following rehabilitation  
Role: Co-PI 
 
7. Seed Grant Trumbower\/Ting (PIs) 7\/12-6\/14 $100K 
Petit Institute for Interdisciplinary Research  <\/strong>
Acute intermittent hypoxia-induced enhancement of locomotor muscle coordination in persons with incomplete spinal cord injury <\/em> 
To quantify deficits in locomotor muscle coordination in persons with spinal cord injury, and improvements following acute intermittent hypoxia treatment.  
 
8. NIH R01 HD46922-06 Ting (PI) 4\/09-3\/15(NCE to 3\/16) $1.7 M  
Neuromechanical Modeling of Postural Responses<\/em>  <\/strong>
The goal is to analyze and model musculoskeletal coordination in the cat hindlimb during balance responses in normal and neurologically impaired animals. 
 
9. GT Neural Engineering Center Seed Grant    Ting (PI) 1\/15-6\/16 $20K 
Measuring and manipulating cortical brain activity for human balance<\/em> <\/strong>
To measure changes in electroencephalographic (EEG) event related potentials (ERPs) during perturbation to standing balance,and alter them with transcranial magnetic stimulation (TMS). 
 
10. NIH R21 HD075612 Ting (PI) 8\/13-5\/15 (NCE to 5\/17) $450K  
Mechanisms of improvement in neurorehabilitation of Parkinson’s Disease<\/em> <\/strong>
To investigate improvements in balance following adapted tango rehabilitation are mediated by basal-ganglia versus cerebellar plasticity. 
 
11. NIH R01 HD082174 Trumbower (PI) 9\/14-6\/17 $2.5M ($100K) 
Mechanisms of intermittent hypoxia-induced motor recovery in persons with chronic SCI<\/em> <\/strong>
To examine how a novel breathing intervention affect recovery of walking ability and is affected by genetic constraints and competition of cellular pathways of neural plasticity. 
Role:<\/strong> co-I (5%) to aid in examination of muscle coordination and biomechanics 
 
12. NSF EFRI 1137229 Ting (PI)  10\/11-9\/15 (NCE to 9\/17)  $2M total ($1.2 M) 
EFRI M3C: Partnered Rehabilitative Movement: Cooperative human-robot interaction for motor rehabilitation, learning, and communication<\/em><\/strong> 
To develop novel predictive models for motor cooperation based on haptic interaction that forge new paths toward fully automated robots that can physically to enhance, assist, and improve motor skills in humans with varying motor capabilities. 
 
13. NCSRR Pilot Project Fregly (PI) 1\/17-12\/17 
Computational Design of FastFES Rehabilitation to Improve Post-Stroke Gait <\/strong>
Role:<\/strong> Co-I for collection and analysis of data 
 
14. NIH R01 NR016151 Shen (PI) 8\/15-8\/18 $1.1M ($180K) 
NRI: Collaborative Research: Quadrupedal Human-Assistive Robotic Platform (Q-HARP)<\/em> <\/strong>
Our role is to measure interaction forces between caregivers frail older adults during assisted walking in order to provide design target for an assistive robot.   
Role:<\/strong> collaborative PI (6%) 
 
15. GT\/GSU Center for Advanced Brain Imaging Ting (PI) 7\/1\/16-6\/31\/17 
Neuroimaging to predict gait rehabilitation outcomes post-stroke<\/em> <\/strong>
To identify whether brain structure and resting state connectivity predict responders and non-responders to gait rehabilitation. 
  
16. Udall Pilot Grant Ting, Factor  (PI) 6\/17-11\/18 $30K 
Common neurophysiological markers underlying cognitive and balance deficits in Parkinson\u2019s disease   <\/em> <\/strong>
 
17. NIH R01 HD46922-S1 Ting (PI) 6\/19-5\/21 $0.1M  
Minority supplement to Alejandro Lopez<\/em> <\/strong>
 
18. NSF DGE 1545287 Howard (PI) 9\/15 \u2013 8\/20 $3M total ($50K) 
NRT:Accessibility, Rehabilitation and Movement Science (ARMS): An Interdisciplinary Traineeship Program in Human-Centered Robotics<\/em> <\/strong>
Role:<\/strong> Co-PI (4%)   
 
19. NIH R01 HD90642 Ting (PI) 9\/16-5\/21 $1.7M ($700K) 
Collaborative Research: Multi-scale models of muscle spindles for understanding sensorimotor control<\/em> <\/strong>
To develop muscle model based on cross-bridge, musculotendon, and neuron properties that accounts for behaviorally-relevant history-dependent behaviors of sensory encoding in muscle spindles proprioceptive afferents. 
Role:<\/strong> PI (20%) 
 
20. NIH R01 HD46922-11 Ting (PI)  9\/17-5\/22 (NCE to \u201823) $3.6M  
Neuromechanical Modeling of Postural Responses: Mechanisms of balance impairments in Parkinson\u2019s disease<\/em>  <\/strong>
To identify the causal role of abnormal muscle activity associated with Parkinsonian rigidity on postural instability through integrated experiments and simulations of reactive balance. 
Role:<\/strong> PI (30%) 
 
21. NSF CMMI M3X 1762211 Ting (PI) 6\/18-5\/23    $900K ($367K) 
Collaborative Research: Enhanced gait dynamics via physical human-human and human-robot interactions at the hands<\/em> <\/strong>
To generate data-driven, predictive models of human gait that capture the effects of human gait assistance and use these to develop a novel gait assistance robotic platform. 
Role:<\/strong> PI (10%) 
 <\/td><\/tr><\/tbody><\/table><\/figure>\n<\/details>\n\n\n\n
Previous Mentored Awards<\/summary>\n
1. ACTSI KL2 McKay (PI) 8\/14 \u2013 7\/16 $150K  
Mentored Clinical and Translational Research Scholars (MCTRS)  <\/strong>
Reactive Balance to Identify Disease Phenotypes and Predict Falls in Parkinson\u2019s Disease<\/em> 
Role: Mentor (0%) 
 
2. T32 Translational Neurology Allen (PI) 7\/14-6\/15 $50K 
Cortical connectivity during functional balance reactions in stroke survivors<\/em> <\/strong>
Role: Mentor (0%) with Kesar 
 
3. NIH F32 NS087775 Allen (PI) 7\/15 \u2013 6\/17 $115K 
Muscle coordination changes affecting impaired balance control post-stroke.<\/em> <\/strong>
Role: Mentor (0%) 
 
4. NIH F31 NS093855 Blum (PI) 8\/15-8\/18 $129K 
Proprioceptive models for control of movement<\/em> <\/strong>
Role: Mentor (0%) 
 
5. NIH K25 HD086276 McKay (PI) 9\/16-8\/20 $450K 
Neural mechanisms of balance deficits, falls, and freezing of gait in Parkinson\u2019s disease<\/em> <\/strong>
Role<\/strong>: Mentor (0%) 
 
6. Banting Postdoctoral Fellowship Horslen (PI) 5\/18-4\/20 $130K 
CIHR: Canadian Institutes of Health Research <\/strong>
How current movement shapes future sensory feedback: A multiscale investigation of how changing muscle mechanics affects muscle spindle sensory feedback and control of standing balance<\/em> 
Role<\/strong>: Mentor (0%) 
 
7. AHA Postdoctoral Fellowship Palmer (PI) 9\/18-8\/20 $150K 
Cortical connectivity during functional balance reactions in stroke survivors<\/em> <\/strong>
Role<\/strong>: Co-Mentor (0%) with Borich 
 
8. NIH F32 HD096816 Palmer (PI) 2\/19-8\/21 $150K 
Cortical connectivity during functional balance reactions in stroke survivors<\/em> <\/strong>
Role<\/strong>: Co-Mentor (0%) with Borich 
 
9. NIH T32 Translational Neurology Mirdamadi (PI)7\/20-6\/21 $50K 
Neural correlates of whole-body motion perception during balance perturbations in stroke survivors and their relationship to balance function<\/em>  <\/strong>
Role:<\/strong> Co-sponsor (0%) with sponsor Borich 
 
10. NSF GRFP Winner (PI) 2019-2022 $150K <\/strong>
 
11. McCamish Postdoctoral Fellowship Beck (PI) 7\/21-1\/23 $90K 
Muscle coactivation and balance control in older adults with and without Parkinson\u2019s disease<\/em> <\/strong>
Role:<\/strong> Sponsor (0%) 
 
12. NSF GRFP Boebinger (PI) 2020-2023 $150K 
Cortical sensorimotor control mechanisms of reactive balance in health and disease<\/em> <\/strong>
 
13. NIH F32 HD105458 Mirdamadi (PI) 7\/21-6\/23 $120K 
Neural correlates of whole-body motion perception during balance perturbations in stroke   survivors and their relationship to balance function<\/em>  <\/strong>
Role:<\/strong> Co-sponsor (0%) with sponsor Borich <\/td><\/tr><\/tbody><\/table><\/figure>\n<\/details>\n","protected":false},"excerpt":{"rendered":"

Federal Funding 1. NIH EB T32\u00a0EB025816\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Stanley\/Ting (MPI)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a07\/19-6\/29\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0$2MTraining in Computational Neural EngineeringAn innovative training program at Georgia Tech and Emory University to train the next generation of researchers at the intersection of computational neuroscience, data science, and clinical neurophysiology.\u00a02. NIH R01\u00a0HD90642-06\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Ting\/Cope\/Sawicki (MPIs)6\/21-5\/26\u00a0\u00a0\u00a0\u00a0\u00a0$3.5M ($1.5M)Multi-scale models of\u00a0proprioceptive encoding to reveal mechanisms of impaired sensorimotor controlTo develop integrated models […]<\/p>\n","protected":false},"author":8815,"featured_media":0,"parent":77,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"disabled","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"disabled","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-1731","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/scholarblogs.emory.edu\/neuromechanicslab\/wp-json\/wp\/v2\/pages\/1731","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/scholarblogs.emory.edu\/neuromechanicslab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/scholarblogs.emory.edu\/neuromechanicslab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/scholarblogs.emory.edu\/neuromechanicslab\/wp-json\/wp\/v2\/users\/8815"}],"replies":[{"embeddable":true,"href":"https:\/\/scholarblogs.emory.edu\/neuromechanicslab\/wp-json\/wp\/v2\/comments?post=1731"}],"version-history":[{"count":17,"href":"https:\/\/scholarblogs.emory.edu\/neuromechanicslab\/wp-json\/wp\/v2\/pages\/1731\/revisions"}],"predecessor-version":[{"id":3177,"href":"https:\/\/scholarblogs.emory.edu\/neuromechanicslab\/wp-json\/wp\/v2\/pages\/1731\/revisions\/3177"}],"up":[{"embeddable":true,"href":"https:\/\/scholarblogs.emory.edu\/neuromechanicslab\/wp-json\/wp\/v2\/pages\/77"}],"wp:attachment":[{"href":"https:\/\/scholarblogs.emory.edu\/neuromechanicslab\/wp-json\/wp\/v2\/media?parent=1731"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}