Recent Publications

  1. “General Access to the Vinca and Tacaman Alkaloids Using a Rh(II)-Catalyzed Cyclization/Cycloaddition Cascade ; A. Padwa and D. England J. Org. Chem. 73, 2792 (2008).
  2. “A Rh(II)-Catalyzed Cycloaddition Approach Toward the Synthesis of Komaroviquinone ; A. Padwa and D. England Tetrahedron 64, 4758 (2008).
  3. “Utilization of a Michael Addition: Dipolar Cycloaddition Cascade for the Synthesis of Cylindricine C ; A. Padwa, A. Flick and M. J. A. Caballero Organic Letters 10, 1871 (2008).
  4. “A General Synthetic Entry to the Pentacyclic Strychnos Alkaloid Family Using a [4+2]-Cycloaddition/Rearrangement Cascade Sequence ; A. Padwa, J. Boonsombat, H. Zhang, M. J. Chughtai, and J. Hartung, Jr. J. Org. Chem. 73, 3539 (2008).
  5. “Gold-Catalyzed Intramolecular Cycloisomerization of Indolo Substituted Propargyl-carboxamides: Application Towards the Synthesis of Lavendamycin Analogues ; A.Padwa and D. England Organic Letters 10, 3631 (2008).
  6. “A New Route to Heterocyclic Compounds by the Mercuric Acetate Oxidation of N-Alkyl Substituted 4-Piperidones ; A. Padwa and A. C. Flick Tetrahedron Letters 49, 5739 (2008).
  7. “Gold- and Silver-Mediated Cycloisomerizations of N-Propargylamides ; G. Verniest and A. Padwa Organic Letters 10, 4379 (2008).
  8. “Cycloaddition Across the Benzofuran Ring as an Approach to the Morphine Alkaloids ; S. France, J. Boonsombat, C. Leverett and A. Padwa J. Org. Chem. 73, 8120 (2008).
  9. “A Stereoselective Approach to the Azaspiro[5.5]undecane Ring System Using a Conjugate Addition/Dipolar Cycloaddition Cascade: Application to the Total Synthesis of 2,7,8-epi-Perhydrohistrionicotoxin ; A. Padwa and M. Wilson J. Org. Chem. 73, 9601 (2008).
  10. “The Rhodium(II) Carbenoid Cyclization-Cycloaddition Cascade of alpha-Diazo Dihydro-indolinones for the Synthesis of Novel Azapolycyclic Ring Systems ; A. Padwa, D. B. England, J. M. Eagan, G.Merey, and O. Anac Tetrahedron 64, 988 (2008).
  11. “Synthesis of 2,4-Disubstituted Pyrroles by Rearrangements of 2-Furanyl Carbamates ; A. Padwa, S. Kiren, X. Hong, and C. A. Leverett Organic Letters 11, 1233 (2009).
  12. “Conjugate Addition-Dipolar Cycloaddition Cascade for the Synthesis of Benzo[a]quinolizine and Indolo[a]quinolizine Scaffolds: Application for the Total Synthesis of Yohimbenone ; A. Padwa, C. J. Stearman and M. Wilson J. Org. Chem. 74, 3491 (2009).
  13. “Cycloaddition Studies Directed Toward the Srychnos Alkaloid Minfiensine ; A. Padwa, D. R. Bobeck, S. France, C. A. Leverett, and F. Sanchez-Cantalej Tetrahedron Lett. 50, 3145 (2009).
  14. “A Chemistry Cascade: From Physical Organic Studies of Alkoxy Radicals to Alkaloid Synthesis ; A. Padwa J. Org. Chem. 74, 6421 (2009).
  15. “A Facile Synthesis of 5-Alkoxypyrrol-2(5H)-ones Using a Modified Aza-Achmatowicz Oxidation ; S. Kiren, X. Hong, C. A. Leverettt, and A. Padwa Tetrahedron 65, 6720 (2009).
  16. “Application of Cross Conjugated Heteroaromatic Betaines Toward the Synthesis of the Schizozygane Alkaloid Strempeliopine ; A. Padwa, C. A. Leverett and X. Hong Acta Chim. Slov 56, 527 (2009).
  17. “Total Synthesis of the Alkaloid Aspidophytine Based on Carbonyl Ylide Cycloaddition Chemistry ; D. R. Bobeck, H. Lee, A. C. Flick, and A. Padwa J. Org. Chem. 74, 7389 (2009).
  18. “Heteroaryl Cross-Coupling as an Entry toward the Synthesis of Lavendamycin Analogues: A Model Study ; A. Padwa, G. Verniest, X. Wang and N. De Kimpe J. Org. Chem. 75, 424 (2010).
  19. “Synthesis of Substituted beta-Carbolines via Gold(III)-Catalyzed Cycloisomerization of N-Propargylamides ; G. Verniest, D. England, N. De Kimpe and A. Padwa Tetrahedron 66, 1496 (2010).
  20. “2,3-Bis(phenylsulfonyl)-1,3-butadiene as a Reagent for the Synthesis of the Azatricyclic Core of Halichlorine ; A. C. Flick, M. J. A. Caballero, H. Ik Lee, and A. Padwa J. Org. Chem. 75, 1992 (2010).
  21. “A Conjugate Addition/Dipolar-Cycloaddition Cascade Sequence for the Synthesis of Cylindricine ; A. C. Flick, M. J. A. Caballero, A. Padwa Tetrahedron 66, 3643 (2010).
  22. “Intramolecular [4+2]-Cycloaddition of 5-Amino-Substituted Oxazoles as an Approach toward the Left-Hand Segment of Haplophytine ; M. Chughtai, J. M. Eagan, and A. Padwa Synlett 21, 215 (2011).
  23. “Synthesis of N-vinyl substituted indoles and their acid-catalyzed behavior ; H. Li, N. Boonnak, A. Padwa Tetrahedron Lett. 52, 2062 (2011).
  24. “An IMDAF Cycloaddition Approach toward the Synthesis of the Lycopodium Alkaloid Fawcettidine ; J. Boonsompat and A.Padwa J. Org. Chem 76, 2753 (2011).
  25. “Intramolecular Diels-Alder Cycloaddition/Rearrangement Cascade of an Amidofuran Derivative for the Synthesis of Minfiensine ; G. Li and A. Padwa Organic Letters 13, 3767 (2011).
  26. “Intramolecular Cycloaddition of Carbonyl Ylides as a Strategy for Natural Product Synthesis ; A. Padwa Tetrahedron 67, 8057 (2011).
  27. “An Approach Toward The Alkaloid Mersicarpine Using a Rhodium(II) Carbenoid Cyclization–Cycloaddition Cascade of an alpha-Diazo Dihydroindolinone ; H. Li, B. Cheng, N. Boonnak, and A. Padwa Tetrahedron 67, 9829 (2011).
  28. “N-Alkenyl Indoles as Useful Intermediates for Alkaloid Synthesis ; H. Li, N. Boonnak and A. Padwa J. Org. Chem. 76, 9488 (2011).
  29. “2,3-Bis(phenylsulfonyl)-1,3-butadiene as a Reagent for the Synthesis of Azapolycylic Ring Systems ; A. C. Flick and A. Padwa J. Sulfur Chemistry 34, 7 (2013).
  30. “2,3-Bis(phenylsulfonyl)-1,3-butadiene as a Reagent for the Synthesis of Piperidone Derivatives ; A. C. Flick and A. Padwa J. Sulfur Chemistry 34, 88 (2013).
  31. “Use of Sulfur Fragments for the Synthesis of Nitrogen Heterocycles ; A. Padwa Pure Appl. Chem 85, 701 (2013).
  32. “Rh(II)-Catalyzed Reactions of Differentially 2-Substituted Bis(diazo) Functionalities ; S. A. Bonderoff and A. Padwa Organic Letters 15, 4114 (2013).
  33. “Natural Product Synthesis via the Rhodium Carbenoid Mediated Cyclization of Diazo Carbonyl Compounds ; A. Padwa, B. Cheng and Y. Zou Aust. J. Chem 67, 343 (2014).
  34. “Model Studies Directed Toward the Alkaloid Mersicarpine Utilizing a Rh(II)-Catalyzed Insertion/Cycloaddition Sequence ; H. Li, S. Bonderoff, B. Cheng and A. Padwa J. Org. Chem. 79, 392 (2014).
  35. “Intramolecular Cycloaddition Reactions of Furo[3,4-b]indoles for Alkaloid Synthesis ; Y. Zou, B. Cheng, H. Li, N. Downer-Riley and C. Straub J. Org. Chem. 79, 3173 (2014).
  36. “Rhodium(II) Catalyzed Cyclopropanation/Cycloaddition Reactions of the Bis(diazo)-piperidin-2- one System ; S. A. Bonderoff and A. Padwa Tetrahedron Letters 76, 9488 (2011).
  37. “Solvent and Ligand Effects Associated with the Rh(II)-Catalyzed Reaction of Diazo Substituted Amido Esters ; A. Padwa and Y. Zou J. Org. Chem. 80, 1802 (2015).
  38. “IMDAF Cascade Approach toward the Synthesis of the Alkaloid (±)-Minfiensine” C. A. Leverett, G. Li, S. France and A. Padwa J. Org. Chem. 81, 10193 (2016).
  39. “Polycyclic Ring Formation Using Bis-diazolactams for Cascade Stitching” S. A. Bonderoff and A. Padwa J. Org. Chem. 82, 642 (2017).

Reviews & Book Chapters

  1. “Cycloaddition Methodology: A Useful Entry Towards Biologically Active Heterocycles; U. Chiacchio, A. Padwa and G. Romeo, Current Organic Chemistry, 13, pp 422-447 (2009).
  2. “Domino Reactions of Rhodium(II) Carbenoids for Alkaloid Synthesis; U. Chiacchio, A. Padwa and G. Romeo, Chem. Soc. Rev., 38, pp 3072-3095 (2009).
  3. “Cascade Reactions of Carbonyl Ylides for Heterocyclic Synthesis ; A. Padwa, Progress in Heterocyclic Chemistry, Chapter 2, G. W. Gribble and J. A. Joule, eds, Elsevier, Vol 20, pp 20-46 (2009).
  4. “Aziridines and Azirines, Monocyclic ; A. Padwa in Comprehensive Heterocyclic Chemistry, Vol III, A. R. Katritzky, Ed., Elsevier, Vol 18, pp 1-97 (2008).
  5. “Three Membered Ring Systems ; A. Padwa and S. S. Murphree, Progress in Heterocyclic Chemistry, Chapter 3.1, G. W. Gribble and J. A. Joule eds, Pergamon Press, Vol 18, pp 55-80 (2007).
  6. “The Synthesis of Heterocycles Using Cascade Chemistry; Advances in Heterocyclic Chemistry, Elsevier; Katritzky, A., Ed., Vol 94, 2007, pp 1-105
  7. “Utilization of 1,2-Thioalkyl Shifts for Alkaloid Synthesis; A. Padwa Phosphorus, Sulfur, and Silicon, and the Related Elements 180, p 1149 (2005)
  8. “Highly Stereoselective Vinylogous Pummerer Rearrangement; J. L. G. Ruano, J. Alem‡n, M. T. Aranda, M. J. ArÂŽvalo, and A. Padwa, Phosphorus, Sulfur, and Silicon, and the Related Elements 180, p 1497 (2005)
  9. “Three Membered Ring Systems” A. Padwa and S. S. Murphree, Progress in Heterocyclic Chemistry, Chapter 3, G. W. Gribble and J. A. Joule, eds, Pergamon Press, Vol 16, pp 54-81 (2004)
  10. “Heteroatom Analogues of Aldehydes and Ketones: An Introduction; A. Padwa Science of Synthesis, Vol 27, A. Padwa, Ed., G. Thieme Verlag, Stuttgart, Germany, pp 1-20 (2004)
  11. “The Pummerer Reaction: Methodology and Strategy for the Synthesis of Heterocyclic Compounds; A. Padwa and S. Bur, Chem. Reviews 104, 2401 (2004)
  12. “Cycloaddition and Cyclization Chemistry of 2H-Azirines; A. Padwa Advances in Heterocyclic Chemistry 99, 1 (2010)
  13. “Ammonium Ylides as Building Blocks for Alkaloid Synthesis; S. Bur and A. Padwa Modern Tools for the Synthesis of Complex Bioactive Molecules, John Wiley, 455 (2012)
  14. “Intramolecular Diels-Alder Cycloaddition of Furans (IMDAF) for Natural Product Synthesis; A. Padwa and A. C. Flick Advances in Heterocyclic Chemistry 110, 1 (2013)
  15. “[4+2]-Cycloaddition Chemistry of Substituted Furans” A. Padwa Methods and Applications of Cycloaddition Reactions in Organic Syntheses, John Wiley , 355 (2014)
  16. “Recent Advances of 1,3-Dipolar Cycloaddition Chemistry for Alkaloid Synthesis”, ” A. Padwa Advances in Heterocyclic Chemistry Vol 119, Elsevier, 241 (2016)
  17. “Asymmetric Reactions Employing 1,3-Dipoles” A. Padwa and S. Bur Chem. Heterocycl. Compd. Vol 52, (2016)
  18. “Cycloaddition Chemistry of Carbonyl Ylides for Alkaloid Synthesis” A. Padwa Russ. Chem. Bull. (Int. Ed.) Vol 65 , 2183 (2016)
  19. “Use of Rhodium Carbenoid Intermediates for Dipolar Cycloaddition Chemistry” A. Padwa, Progress in Heterocyclic Chemistry, Chapter 2, G. W. Gribble and J. A. Joule, eds, Elsevier Science, Vol 29, pp 45-64 (2017).
  20. “Use of Nitrogen and Oxygen Dipole Ylides for Alkaloid Synthesis. A. Padwa (GG-10416UR) ARKIVOC e-Journal Vol. 20, Part IV, DOI: https://doi.org/10.24820/ark.5550190.p010.416, pp 23-49, 2018.