2018 Publications

83. Josephson, L., Stratman, N., Liu, Y., Qian, F., Liang, S. H., Vasdev, N. and Patel, S.  “The Binding of BF-227-Like Benzoxazoles to Human α-Synuclein and Amyloid β Peptide Fibrils” Mol. Imaging, 2018, ASAP, DOI: 10.1177/1536012118796297.

 

82. Fu, H., Chen, Z., Josephson, L., Li, Z. and Liang, S. H.   “Positron Emission Tomography (PET) Ligand Development for Ionotropic Glutamate Receptors: Challenges and Opportunities for Radiotracer Targeting N-methyl-D-aspartate (NMDA), alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) and Kainate Receptors”  J. Med. Chem., 2018, ASAP, DOI: 10.1021/acs.jmedchem.8b00714. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393217/

 

81. Chen, Z., Mori, W., Zhang, X., Yamasaki, T., Dunn, P. J., Zhang, G. W., Fu, H., Shao, T., Zhang, Y., Hatori, A., Ma, L., Fujinaga, M., Xie, L., Deng, X., Li, H., Yu, Q., Rong, J., Josephson, L., Ma, J., Shao, Y., Tomita, S., Zhang, M. R., and Liang, S. H.    “Synthesis and preclinical evaluation of 11C-labeled 1,3-dihydro-2H-benzo[d]imidazol-2-ones for imaging studies towards γ8-dependent transmembrane AMPA receptor regulatory protein”   Eur. J. Med. Chem., 2018, 157, 898-908. PMC article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245653

 

80. Cheng, S., Jacobson, O., Zhu, G., Chen, Z., Liang, S. H., Tian, R., Yang, Z., Niu, G., Zhu, X and Chen, X.  “PET imaging of EGFR expression using an 18F-labeled RNA aptamer”  Eur. J. Nucl. Med. Mol. Imaging, 2018, ASAP, DOI: 10.1007/s00259-018-4105-1.

 

79. Zheng, C., Wang, Y., Xu, Y., Chen, Z., Chen, G., and Liang, S. H.   “Ru-Photoredox-Catalyzed Decarboxylative Oxygenation of Aliphatic Carboxylic Acids through N-(acyloxy)phthalimide”  Org. Lett., 2018, 20164824-4827.   DOI: https://doi.org/10.1021/acs.orglett.8b01885

 

78. Deng, X., Rong, J., Wang, L., Vasdev, N., Zhang, L., Josephson, L., and Liang, S. H.   “Chemistry for Positron Emission Tomography: Recent Advances in 11C-, 18F-, 13N- and 15O-labeling Reactions”  Angew. Chem. Int. Ed., 2018, ASAP. DOI: 10.1002/anie.201805501. PMC: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405341

 

77. Rong, J. and Liang, S. H. “Aliphatic [18F]Fluorination Chemistry for Positron Emission Tomography”, in Synthetic Organofluorine Chemistry, Springer, Hu, J. & Umemoto, T., Eds. Springer Singapore: Singapore, 2018; pp 1-14.

 

76. Yamasaki, T., Mori, W., Zhang, Y., Hatori, A., Fujinaga, M., Wakizaka, H., Kurihara, Y., Wang, L., Nengaki, N., Ohya, T., Liang, S. H. and Zhang, M-R. “First demonstration of in vivo mapping for regional brain monoacylglycerol lipase using PET with [11C]SAR127303″ NeuroImage, 2018, accepted. DOI: 10.1016/j.neuroimage.2018.05.015.

 

75. Collier, T. L.; Dahl, K.; Stephenson, N. A.; Holland, J. P.; Riley, A.; Liang, S. H. and Vasdev, N.  “Recent applications of a single quadrupole mass spectrometer in 11C, 18F and radiometal chemistry” J Fluorine Chem, 2018, accepted.

 

 

74. Cheng, R.; Mori, W.; Ma, L.; Alhouayek, M.; Hatori, A.; Zhang, Y.; Ogasawara, D.; Yuan, G.; Chen, Z.; Zhang, X.; Shi, H.; Yamasaki, T.; Xie, L.; Kumata, K.; Fujinaga, M.; Nagai, Y.; Minamimoto, T.; Svensson, M.; Wang, L.; Du, Y.; Ondrechen, M.; Vasdev, N.; Cravatt, B. F.; Fowler, C.; Zhang, M-R. and Liang, S. H.  “In vitro and in vivo evaluation of 11C-labeled azetidine-carboxylates for imaging monoacylglycerol lipase by PET imaging studies”  J Med Chem, 2018, 61, 2278-2291.   DOI: 10.1021/acs.jmedchem.7b01400. [link] [full-text]

 

73. Krishnan, H. S.; Bernard-Gauthier, V.; Placzek, M. S.; Dahl, K.; Narayanaswami, V.; Livni, E.; Chen, Z.; Yang, J.; Collier, T. L.; Ran, C.; Hooker, J. M.; Liang, S. H. and Vasdev, N. “Metal protein-attenuating compound for PET neuroimaging: synthesis and preclinical evaluation of [11C]PBT2” Mol Pharm, 2018, 15, 695-702. DOI: 10.1021/acs.molpharmaceut.7b00936 [link]