{"id":140,"date":"2023-02-25T06:58:15","date_gmt":"2023-02-25T06:58:15","guid":{"rendered":"https:\/\/scholarblogs.emory.edu\/radiochem\/?page_id=140"},"modified":"2025-02-13T05:17:28","modified_gmt":"2025-02-13T05:17:28","slug":"research","status":"publish","type":"page","link":"https:\/\/scholarblogs.emory.edu\/radiochem\/research\/","title":{"rendered":"Research"},"content":{"rendered":"\n<h3><span style=\"color: #3366ff\"><strong>Translational Radiochemistry<br><\/strong><\/span><\/h3>\n<p>Compared to diversity of synthetic organic chemistry methods,&nbsp;only limited radiochemical methods are available to introduce PET isotopes, including fluorine-18 (<sup>18<\/sup>F, <em>t<\/em><sub>1\/2<\/sub>=109.7 min) and carbon-11 (<sup>11<\/sup>C, <em>t<\/em><sub>1\/2<\/sub>=20.3 min). Therefore we strive to develop novel methods to radiolabel important molecules that were previously inaccessible, and hope to establish a general platform (&#8216;radiochemical toolbox&#8217;) to promote PET imaging research.&nbsp;<\/p>\n<p>Learn more about <a href=\"https:\/\/scholarblogs.emory.edu\/radiochem\/research\/feature-slider-1\/\">&#8216;Translational Radiochemistry&#8217;<\/a><\/p>\n\n\n\n<p><strong><img decoding=\"async\" src=\"http:\/\/scholarblogs.emory.edu\/radiochem\/files\/2023\/02\/home-page-3.jpg\" alt=\"This image has an empty alt attribute; its file name is home-page-3.jpg\"><\/strong><\/p>\n<h3>&nbsp;<\/h3>\n<h3>&nbsp;<\/h3>\n<h3>&nbsp;<\/h3>\n<h3><strong><span style=\"color: #3366ff\">A List of Radioactive Drugs &amp; PET Ligands Under Development<\/span><\/strong><\/h3>\n<p><a href=\"https:\/\/scholarblogs.emory.edu\/radiochem\/technology\/\">See list here<\/a><\/p>\n<p style=\"text-align: left\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1420 alignleft\" src=\"https:\/\/scholarblogs.emory.edu\/radiochem\/files\/2024\/08\/Slide1.png\" alt=\"\" width=\"569\" height=\"427\" srcset=\"https:\/\/scholarblogs.emory.edu\/radiochem\/files\/2024\/08\/Slide1.png 1200w, https:\/\/scholarblogs.emory.edu\/radiochem\/files\/2024\/08\/Slide1-300x225.png 300w, https:\/\/scholarblogs.emory.edu\/radiochem\/files\/2024\/08\/Slide1-1024x768.png 1024w, https:\/\/scholarblogs.emory.edu\/radiochem\/files\/2024\/08\/Slide1-768x576.png 768w, https:\/\/scholarblogs.emory.edu\/radiochem\/files\/2024\/08\/Slide1-350x263.png 350w, https:\/\/scholarblogs.emory.edu\/radiochem\/files\/2024\/08\/Slide1-780x586.png 780w, https:\/\/scholarblogs.emory.edu\/radiochem\/files\/2024\/08\/Slide1-250x188.png 250w\" sizes=\"auto, (max-width: 569px) 100vw, 569px\" \/><\/p>\n\n\n\n<h3>\u00a0<\/h3>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<h3><span style=\"color: #0000ff\"><strong><span style=\"color: #3366ff\">Drug Targets for Radiopharmaceuticals (categorized by signaling pathways)<br \/><\/span><\/strong><\/span><\/h3>\n<ul>\n<li><a href=\"https:\/\/scholarblogs.emory.edu\/radiochem\/research\/feature-slider-2\/\">Cholesterol Metabolism in the Central Nervous System<\/a><\/li>\n<li><a href=\"https:\/\/scholarblogs.emory.edu\/radiochem\/research\/featured-slider-4\/\">Endocannabinoid Signaling System<\/a><\/li>\n<li><a href=\"https:\/\/scholarblogs.emory.edu\/radiochem\/research\/feature-slider-3\/\">Glutamate Receptor System (ionotropic and metabotropic)<\/a><\/li>\n<li class=\"LC20lb MBeuO DKV0Md\"><a href=\"https:\/\/scholarblogs.emory.edu\/radiochem\/research\/phosphodiesterase-pde-system\/\">Phosphodiesterase (PDE) System<\/a><\/li>\n<li>Ion channels<\/li>\n<li>GPCR Orphan Receptors<\/li>\n<\/ul>\n<p>\u00a0<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-788 alignleft\" src=\"https:\/\/scholarblogs.emory.edu\/radiochem\/files\/2023\/10\/Imaging-targets-template-v2.png\" alt=\"\" width=\"588\" height=\"496\" srcset=\"https:\/\/scholarblogs.emory.edu\/radiochem\/files\/2023\/10\/Imaging-targets-template-v2.png 1200w, https:\/\/scholarblogs.emory.edu\/radiochem\/files\/2023\/10\/Imaging-targets-template-v2-300x253.png 300w, https:\/\/scholarblogs.emory.edu\/radiochem\/files\/2023\/10\/Imaging-targets-template-v2-1024x864.png 1024w, https:\/\/scholarblogs.emory.edu\/radiochem\/files\/2023\/10\/Imaging-targets-template-v2-768x648.png 768w\" sizes=\"auto, (max-width: 588px) 100vw, 588px\" \/><\/p>\n<p>\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Translational Radiochemistry Compared to diversity of synthetic organic chemistry methods,&nbsp;only limited radiochemical methods are available to introduce PET isotopes, including fluorine-18 (18F, t1\/2=109.7 min) and carbon-11 (11C, t1\/2=20.3 min). Therefore we strive to develop novel methods to radiolabel important molecules that were previously inaccessible, and hope to establish a general <a class=\"more-link\" href=\"https:\/\/scholarblogs.emory.edu\/radiochem\/research\/\">Read More &#8230;<\/a><\/p>\n","protected":false},"author":8331,"featured_media":0,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-140","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/pages\/140","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/users\/8331"}],"replies":[{"embeddable":true,"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/comments?post=140"}],"version-history":[{"count":42,"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/pages\/140\/revisions"}],"predecessor-version":[{"id":2352,"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/pages\/140\/revisions\/2352"}],"wp:attachment":[{"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/media?parent=140"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}