{"id":245,"date":"2023-02-25T16:09:39","date_gmt":"2023-02-25T16:09:39","guid":{"rendered":"https:\/\/scholarblogs.emory.edu\/radiochem\/?page_id=245"},"modified":"2026-01-16T05:44:30","modified_gmt":"2026-01-16T05:44:30","slug":"all-publications","status":"publish","type":"page","link":"https:\/\/scholarblogs.emory.edu\/radiochem\/publications\/all-publications\/","title":{"rendered":"All Publications"},"content":{"rendered":"\n<p><strong>280.\u00a0<span style=\"text-decoration: underline\">Liang, S. H.<\/span>\u00a0<\/strong>\u201cFrom Lutetium to Terbium: A New Era in PSMA-Targeted Radioligand Therapy for mCRPC Patients\u201d,\u00a0<em data-start=\"108\" data-end=\"168\">American Journal of Nuclear Medicine and Molecular Imaging<\/em>, 2025, 15, 219\u2013222.<\/p>\n<p><strong>279.\u00a0<span style=\"text-decoration: underline\">Liang, S. H.<\/span><\/strong>\u00a0\u201cPARP-Targeted Molecular Imaging for Noninvasive Diagnosis and Surgical Guidance in Basal Cell Carcinoma\u201d,\u00a0<em data-start=\"120\" data-end=\"180\">American Journal of Nuclear Medicine and Molecular Imaging<\/em>, 2025, 15, 208\u2013211.<\/p>\n<p><strong>278.\u00a0<\/strong>Shi, H.; Li, Y. and\u00a0<span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span>\u00a0\u201cSelective 7-Azaindole Modulators Targeting Fyn and GSK-3\u03b2 for Dual-Target Neuromodulation\u201d,\u00a0<em data-start=\"272\" data-end=\"305\">ACS Medicinal Chemistry Letters<\/em>,<br \/>ASAP. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00728<\/p>\n<p><strong>277. <\/strong>Wu, R.; Rong, J.; Hou, Y.; Yin, C.; Zhou, Y.; Gai, Y.; Haider, A.; Lan, X.; <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span>; Gao, Z. and Xia, X. \u201cS1PR-Targeted PET Imaging: Advancing Insights into Neuroinflammatory and Immune-Related Pathologies\u201d, <em data-start=\"218\" data-end=\"243\">Molecular Pharmaceutics<\/em>, 2025, ASAP. Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/41397090\/<\/p>\n<p><strong>276. <\/strong>Li, Y.; Mori, W.; Song, Z.; Yamasaki, T.; Zhao, T.; Chen, J.; Zhang, Y.; Zhou, X.; Xie, L.; Kokufuta, T.; Hu, K.; Hu, Q.-L.; Fujinaga, M.; Li, X.; Kumata, K.; Li, C.; Sun, Z.; Gao, Y.; Hoyle, D.; Patel, J.; Yuan, H.; Zhang, M.-R.; <span style=\"text-decoration: underline\"><strong>Liang, S. H<\/strong><\/span>. \u201cRadiosynthesis and Preclinical Evaluation of a Novel 11C-labeled Pyrazolopyrimidine Derivatives for Positron Emission Tomography Imaging of Phosphodiesterase 2A\u201d, <em data-start=\"483\" data-end=\"516\">ACS Medicinal Chemistry Letters<\/em>, 2025, ASAP. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00649<\/p>\n<p><strong>275.\u00a0<\/strong>Sabnis, R. W.;<strong>\u00a0<span style=\"text-decoration: underline\">Liang, S. H<\/span>.<\/strong>; Abdel-Magid, A. F.; Rosse, G. and Kargbo, R. B. \u201cPatent Highlights at the Frontier of Neuroscience: From Molecular Targets to Psychedelic Neurotherapeutics\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>, 2025, ASAP. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00699<\/p>\n<p><strong>274. <\/strong>Tay, D.; Ahmed, H.; Dawoud, A.; Salam, M.; Gobbi, L.; Grether, U.; Edelmann, M. R.; Wittwer, M. B.; Collin, L.; Atz, K.; Keaney, J.; Giroud, M.; Rossi, A.; Gennari, A. G.; Pagano, G.; Parrot, N. J.; Barakovic, M.; Rominger, A.; Gebhard, C.; Ametamey, S. M.; Saindane, A. M.; <span style=\"text-decoration: underline\"><strong>Liang, S. H<\/strong><\/span>. and Haider, A. \u201cTranslational molecular imaging and drug development in multiple sclerosis\u201d, <em>Theranostics<\/em>, 2026, 16, 1630\u20131657. Link: https:\/\/www.thno.org\/v16p1630.htm.<\/p>\n<p><strong>273.\u00a0<\/strong>Zhou, X.; Patel, J. S.; Zhao, T. and\u00a0<span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span>\u00a0\u201cThe Promise of Selective PARP1 Inhibitors in Cancer Therapy\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 11, 2103\u20132107. Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/41256971\/<\/p>\n<p><strong>272.<\/strong> Li, Y.; Wang, L.; Pei, Z.; Factor, S. A. and <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span>\u00a0\u201cIsoindolinone-Derived PET Tracers for Molecular Imaging of mHTT Aggregates in Huntington\u2019s Disease\u201d,\u00a0<em data-start=\"231\" data-end=\"264\">ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 11,\u00a0 2097\u20132102. Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/41257000\/<\/p>\n<p><strong>271.<\/strong> Zhao T.; Patel J. S.; Ran C.; and <strong><u>Liang S. H.<\/u><\/strong> \u201cAdvances in PET imaging of oxidative stress: tracer innovation, mechanistic insight, and translational potential\u201d, European Journal of Nuclear Medicine and Molecular Imaging, 2025, Online ahead of print. Link: https:\/\/link.springer.com\/article\/10.1007\/s00259-025-07505-7<\/p>\n<p><strong>270.<\/strong> Patel J. S.; Li R.; and <strong><u>Liang S. H.<\/u><\/strong> \u201cVisualizing T-cell activation: PET imaging of CXCL9 as a window into the tumor immune response\u201d, American Journal of Nuclear Medicine and Molecular Imaging, 2025, 15(5), 212\u2013214. Link: https:\/\/doi.org\/10.62347\/KSFZ9854<\/p>\n<p><strong>269.<\/strong>\u00a0Banke, T. G.; Regan, M. C.; Perszyk, R. E.; Zhang, L.; Xing, H.; Chen, J.; Won, S.; Simorowski, N.; Diaz, E. S.; Kim, S.; Song, R.; Rong, J.; Zhou, X.; Chaudhary, A. F.; Zhang, J.; Traynelis, J. F.; McDaniels, E. D.; Nitsche, K.; Roache, S.; Raymond, C. S.; Low, C.-M.; Myers, S. J.; Roche, K. W.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Traynelis, S. F.; Furukawa, H. and Yuan, H. \u201cInhibition of GluN2B-containing\u00a0<em>N<\/em>-methyl-<em>d<\/em>-aspartate receptors by radiprodil\u201d,\u00a0<em>Brain<\/em>, 2025, Online ahead of print. Link: https:\/\/doi.org\/10.1093\/brain\/awaf355<\/p>\n<p><strong>267.\u00a0<\/strong>Zhao, T.; Haider, A. and <strong><u>Liang S. H.<\/u><\/strong>\u00a0\u201c<sup>18<\/sup>F-Flurpiridaz PET for Imaging of Myocardial Ischemia\u201d,\u00a0<em>Trends in Pharmacological Sciences, 2025, 46, 11, 1146-1147.<\/em>\u00a0Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/40813202\/<\/p>\n<p><strong>266. <u>Liang S. H.<\/u> \u201c<\/strong>Development of Novel PET Tracers for Imaging Non-AD Tauopathies\u201d,\u00a0\u00a0<em data-start=\"150\" data-end=\"183\">ACS Medicinal Chemistry Letters<\/em>,\u00a0<span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 16<\/span><span class=\"cit-issue\">, 9<\/span><span class=\"cit-pageRange\">, 1697\u20131702<\/span>. Link: https:\/\/doi.org\/10.1021\/acsmedchemlett.5c00486<\/p>\n<p><strong>268.\u00a0<\/strong>Zhang, J.-J.; Yang, J.; Patel, J. S.; Lv, R.; Zhang, Z.; Ji, X.; Tang, L.; Chen, Z. and\u00a0<u><strong>Liang, S. H<\/strong>.<\/u>\u00a0\u201cEmerging Molecular PET Imaging for Cell Death in Neurodegenerative Diseases\u201d,\u00a0<em>Journal of Medicinal Chemistry<\/em>, 2025,\u00a0<span class=\"cit-volume\">68<\/span><span class=\"cit-issue\">, 21<\/span><span class=\"cit-pageRange\">, 22033\u201322046<\/span>. Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/41150964\/<\/p>\n<p><strong>265. <u>Liang S. H.<\/u> \u201c<\/strong>Chelator Optimization and Therapeutic Potential of\u00a0<sup>188<\/sup>Re-FAPI for FAP-Targeted Radionuclide Therapy\u201d,\u00a0<em data-start=\"150\" data-end=\"183\">ACS Medicinal Chemistry Letters<\/em>,\u00a0<span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 16<\/span><span class=\"cit-issue\">, 9<\/span><span class=\"cit-pageRange\">, 1697\u20131702<\/span>. Link: https:\/\/doi.org\/10.1021\/acsmedchemlett.5c00486<\/p>\n<p><strong>264.\u00a0<\/strong>Haider, A.; Xiao, Z.; Chen, J.; Pfister, S. K.; Zhou, X.; Li, Y.; Chaudhary, A.; Zhao, C.; Rong, J.; Paehler, A.; Mohr, S.; Norcross, R. D.; Honer, M.; Mu, L.; Gobbi, L.; Schibli, R.; Hoener, M. C. and <strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cPreclinical Development of [<sup>18<\/sup>F]TAAR1-2203 as a PET Radioligand for Imaging TAAR1 Expression and Receptor Occupancy\u201d,\u00a0<em data-start=\"377\" data-end=\"437\">European Journal of Nuclear Medicine and Molecular Imaging<\/em>, 2025.<\/p>\n<p><strong>263.<\/strong> Zhou X.; <strong><u>Liang, S. H.<\/u><\/strong> \u201cDevelopment of Selective PARP1 Inhibitors for Treatment of Cancer\u201d, ACS Medicinal Chemistry Letters, 2025, 16, 10, 1914\u20131917. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00536<\/p>\n<p><strong>262.<\/strong> Zhou X.; <strong><u>Liang, S. H.<\/u><\/strong> \u201cDevelopment of Novel Compounds and Methods for Treatment of PARPs Mediated Disease\u201d, ACS Medicinal Chemistry Letters, 2025, 16, 10, 1910\u20131913. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00530<\/p>\n<p><strong>261. <\/strong>Yang, J.; Yang, Y.; Wang, H.; <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span> and Ran, C. &#8220;Molecular Afterglow of Lophine-Based Luminophore and Its Imaging Applications&#8221;, <em>Angewandte Chemie International Edition<\/em>, 2025, e202507174. Link:\u00a0https:\/\/pubmed.ncbi.nlm.nih.gov\/40852797\/<\/p>\n<p><strong>260.\u00a0<\/strong>Xiao, Z.; Sun, J.; Fujinaga, M.; Wei, H.; Zhao, C.; Haider, A.; Van, R.; Kuang, S.; Yamasaki, T.; Zhang, Y.; Rong, J.; Hu, K.; Chen, J.; Leon, E. C.; Mori, W.; Xie, L.; Wei, J.; Xu, Y.; Shao, Y.; Zhang, H.-T.; Xu, Y.; Ran, C.; Lloyd, K. C. K.; Wang, L.; Zhang, M.-R. and <strong><u>Liang, S. H.<\/u><\/strong><strong>\u00a0<\/strong>\u201cRadiosynthesis and Preclinical Evaluation of a Carbon-11 Labeled Phosphodiesterase 7 Inhibitor for PET Neuroimaging\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>,\u00a0<span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 16<\/span><span class=\"cit-issue\">, 9<\/span><span class=\"cit-pageRange\">, 1835\u20131843<\/span>. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00385<\/p>\n<p><strong>259.\u00a0<u>Liang, S. H.<\/u><\/strong>\u00a0\u201cNovel N-(Pyridin-3-yl)benzamide Derivatives as Histone Acyl Transferase Positive Modulators\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 11, 2147\u20132148. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00554<\/p>\n<p><strong>258.\u00a0<\/strong><u><strong>Liang, S. H.<\/strong><\/u>\u00a0\u201cNovel N-Arylquinoline-4-carboxamide Derivatives as Prostaglandin F Receptor Antagonists\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 11, 2149\u20132151. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00553<\/p>\n<p><strong>257.<\/strong> Zhou X.; <strong><u>Liang, S. H.<\/u><\/strong> \u201cSynthesis of Novel PARP Inhibitors and Their Uses in Treatment of PARPs Related Diseases\u201d, ACS Medicinal Chemistry Letters, 2025, 16, 11, 2152\u20132153. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00577<\/p>\n<p><strong>256.\u00a0<\/strong>Song, Z.; Li, Y.; Dahl, K.; Sun, Z.; Chen, J.; Zhou, X.; Gao, Y.; Rong, J.; Zhao, C.; Yuan, K.; Chaudhary, A. F.; Patel, J. S.; Collier, T. L.; Ran, C.; Muehlfenzl, K. S.; Haider, A.; Elmore, C. S.; Schou, M. and <strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cDevelopment and Preclinical Characterization of [<sup>18<\/sup>F]H3-2406 and [<sup>18<\/sup>F]H3-2407 for Positron Emission Tomography Imaging of the Histamine Subtype-3 Receptor\u201d,\u00a0<i>Journal of Medicinal Chemistry<\/i>,\u00a0<span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 68<\/span><span class=\"cit-issue\">, 15<\/span><span class=\"cit-pageRange\">, 15372\u201315385<\/span>. Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/40665705\/<\/p>\n<p><strong>255.\u00a0<\/strong>Li, Y. and <strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cSelective Modulation of the GluN2B\/C\/D Containing N-Methyl-d-Aspartate Receptors: A New Frontier in Targeted Neurotherapeutics\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>,\u00a0<span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 16<\/span><span class=\"cit-issue\">, 7<\/span><span class=\"cit-pageRange\">, 1226\u20131230<\/span>. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00365<\/p>\n<p><strong>254.<\/strong> Li X.; <strong><u>Liang, S. H.<\/u><\/strong> \u201cImidazo Pyrimidine Compounds for the Inhibition of Oncogenic KRAS Mutations in Cancer Therapy\u201d, ACS Medicinal Chemistry Letters, 2025, 16, 11, 2194\u20132196. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00628<\/p>\n<p><strong>253.<\/strong> Hoyle D. E.; <strong><u>Liang, S. H.<\/u><\/strong> \u201cDesign and Synthesis of Novel USP1 Inhibitors for Therapeutic Applications\u201d, ACS Medicinal Chemistry Letters, 2025, 16, 11, 2197\u20132199. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00627<\/p>\n<p><strong>252.<\/strong> Song Z.; <strong><u>Liang, S. H.<\/u><\/strong> \u201cNovel 2H-Pyrazolo[3,4-d]thiazole Compounds Targeting NLRP3 for the Treatment of Neurodegenerative Diseases\u201d, ACS Medicinal Chemistry Letters, 2025, 16, 11, 2200\u20132201. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00626<\/p>\n<p><strong>251.<\/strong> Hu Q-L.; <strong><u>Liang, S. H.<\/u><\/strong> \u201cNovel Bicyclic Peptides Targeting Interleukin-23 Receptor to Relieve Inflammatory Conditions\u201d, ACS Medicinal Chemistry Letters, 2025, 16, 11, 2202\u20132203. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00625<\/p>\n<p><strong>250. <span style=\"text-decoration: underline\">Liang, S. H<\/span>.<\/strong><strong>\u00a0<\/strong>\u201cTrop2-Targeted ImmunoPET Ligands\u201d,\u00a0<em data-start=\"181\" data-end=\"241\">American Journal of Nuclear Medicine and Molecular Imaging<\/em>, 2025, 15(3):105\u2013108.<\/p>\n<p><strong>249.\u00a0<\/strong>Zhao, T. and <strong><span style=\"text-decoration: underline\">Liang, S. H<\/span>.<\/strong><strong>\u00a0<\/strong>\u201cStreamlining First-in-Human PET Radiopharmaceutical Development: FDA\u2019s Evolving Stance on Preclinical Dosimetry\u201d,\u00a0<em data-start=\"181\" data-end=\"241\">American Journal of Nuclear Medicine and Molecular Imaging<\/em>, 2025, 15(4):171\u2013172.<\/p>\n<p><strong>248.\u00a0<\/strong>Rong, J.; Zhao, C.; Chaudhary, A. F.; Chen, J.; Li, Y.; Zhou, X.; Song, Z.; Sun, Z.; Gao, Y.; Feng, S.; Zhao, T.; Hu, Q.-L.; Li, C.; Haider, A.; Patel, J.; Ran, C.; Yuan, H. and\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cRadiosynthesis and Evaluation of an 18F-Labeled Radioligand for Imaging Metabotropic Glutamate Receptor 3 with Positron Emission Tomography\u201d,\u00a0<em>American Journal of Nuclear Medicine and Molecular Imaging<\/em>, 2025, 15(5), 173-182.<\/p>\n<p><strong>247.\u00a0<\/strong>Rong, J.; Zhao, C.; Chaudhary, A. F.; Chen, J.; Li, Y.; Zhou, X.; Song, Z.; Sun, Z.; Gao, Y.; Feng, S.; Zhao, T.; Hu, Q.-L.; Li, C.; Patel, J. S.; Yuan, H.; Haider, A. and <strong><span style=\"text-decoration: underline\">Liang, S. H<\/span>.<\/strong>\u00a0\u201cDevelopment of Novel 18F-Labeled Selective Orexin-2 Receptor Radioligands for Positron Emission Tomography\u201d,\u00a0<em>ACS Pharmacology &amp; Translational Science<\/em>, 2025, 8, 4070-4079.<\/p>\n<p><strong>246.\u00a0<\/strong>Zhao, T. and <strong><span style=\"text-decoration: underline\">Liang, S. H<\/span>.<\/strong><strong>\u00a0<\/strong>\u201cNovel Tracers and Emerging Targets for Positron Emission Tomography in Alzheimer\u2019s Disease and Related Dementias\u201d,\u00a0<em data-start=\"181\" data-end=\"241\">American Journal of Nuclear Medicine and Molecular Imaging<\/em>, 2025, 15(4):167\u2013170.<\/p>\n<p><strong>245. <span style=\"text-decoration: underline\">Liang, S. H<\/span>. <\/strong>&#8220;DLL3-Targeted ImmunoPET and Radioimmunotherapy Ligands&#8221;, <em data-start=\"181\" data-end=\"241\">American Journal of Nuclear Medicine and Molecular Imaging<\/em>, accepted.<\/p>\n<p><strong>244.\u00a0<\/strong>Zhao, T. and\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cDevelopment of Bicyclic Compounds Containing a Tertiary Amine Moiety as T Cell Activators\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>,\u00a0<span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 16<\/span><span class=\"cit-issue\">, 9<\/span><span class=\"cit-pageRange\">, 1731\u20131732<\/span>. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00496<\/p>\n<p><strong>243.\u00a0<\/strong>Hu, Q. and\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cNovel Cyclic Peptides Trapping Interleukin-1\u03b2 to Relieve Inflammatory and Atherosclerotic Cardiovascular Disease\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>,\u00a0<span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 16<\/span><span class=\"cit-issue\">, 9<\/span><span class=\"cit-pageRange\">, 1733\u20131735<\/span>. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00495<\/p>\n<p><strong>242.\u00a0<\/strong>Rong, J. and\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cNovel Indazole Propionic Acid Derivatives as AMPK Activators\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>,\u00a0<span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 16<\/span><span class=\"cit-issue\">, 9<\/span><span class=\"cit-pageRange\">, 1736\u20131737<\/span>. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00494<\/p>\n<p><strong>241.\u00a0<\/strong>Rong, J. and\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cNovel Pyrido[4,3-d]pyrimidine Compounds as KRAS Inhibitors\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>,\u00a0<span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 16<\/span><span class=\"cit-issue\">, 9<\/span><span class=\"cit-pageRange\">, 1738\u20131739<\/span>. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00493<\/p>\n<p><strong>240.<\/strong> Song, Z.; <strong><u>Liang, S. H.<\/u><\/strong> \u201cNovel Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors for the Treatment of Parkinson\u2019s Disease\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 8, 1511\u20131512. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00438<\/p>\n<p><strong>239.\u00a0<\/strong>Li, C.; Song, Z.; Hu, Q.; Li, Y.; Patel, J. S. and <strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cCD45-targeted PET enables the visualization of inflammatory conditions\u201d,\u00a0<em data-start=\"181\" data-end=\"241\">American Journal of Nuclear Medicine and Molecular Imaging<\/em>, 2025, 15(3):124\u2013129.<\/p>\n<p><strong>238.<\/strong> Zhou, X.; <strong><u>Liang, S. H.<\/u><\/strong> \u201cThe Development of Inhibitors for NLRP3 Inflammasome\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 8, 1513\u20131514. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00437<\/p>\n<p><strong>237.<\/strong> Zhao, T.; <strong><u>Liang, S. H.<\/u><\/strong> \u201cNovel Thieno[3,2-b]Pyridine Derivatives in the Treatment of Huntington\u2019s Disease\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 8, 1515\u20131516. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00436<\/p>\n<p><strong>236.<\/strong> Hu, Q.; <strong><u>Liang, S. H.<\/u><\/strong> \u201cNovel Peptides as GIPR\/GLP-1R\/GCGR Triagonists for Treating Type 2 Diabetes Mellitus\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 8, 1517\u20131519. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00435<\/p>\n<p><strong>235.<\/strong> Zhou, X.; <strong><u>Liang, S. H.<\/u><\/strong> \u201cPreparation of Novel PARP1 Inhibitors and Their Use in Cancer Treatment\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 8, 1494\u20131496. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00411<\/p>\n<p><strong>234.<\/strong> Zhou, X.; <strong><u>Liang, S. H.<\/u><\/strong> \u201cNovel Isoindolinone-Containing PARP Inhibitors: Synthesis and Therapeutic Applications in CNS Cancer Treatment\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 8, 1497\u20131498. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00410<\/p>\n<p><strong>233. <\/strong>Li, Y.; Dahl, K.; Elmore, C. S.; Sandell, J.; Takano, A.; Halldin, C.; Farde, L.; Ahlgren, C.; Cochrane, A.; Rong, J.; Chen, J.; Zhao, C.; Zhou, X.; Patel, J. S.; Song, Z.; Chaudhary, A.; Gao, Y.; Sun, Z.; Zhang, Z.; Feng, S.; Haider, A.; <span style=\"text-decoration: underline\"><strong>Liang, S. H<\/strong><\/span>.; Schou, M. &#8220;Radiosynthesis and Evaluation of 11C-Labeled Imidazolyl Pyrimidine Derivatives for Positron Emission Tomography Imaging of Glycogen Synthase Kinase-3&#8221;, <em>ACS Pharmacology &amp; Translational Science<\/em>, <span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 8<\/span><span class=\"cit-issue\">, 7<\/span><span class=\"cit-pageRange\">, 1986\u20131995<\/span>.<\/p>\n<p><strong>232.\u00a0<\/strong>Li, Y. and <strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cNovel Isoindolin-1-one Derivatives as Metabotropic Glutamate Receptor Positive Allosteric Modulators\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>, \u00a0<span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 16<\/span><span class=\"cit-issue\">, 7<\/span><span class=\"cit-pageRange\">, 1249\u20131250<\/span>.<\/p>\n<p><strong>231.\u00a0<\/strong>Zhou, X. and <strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cTargeted Treatment of Cancer by Using Conjugate Compounds with Poly(ADP-ribose) Polymerase (PARP) Inhibitors\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>,\u00a0<span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 16<\/span><span class=\"cit-issue\">, 7<\/span><span class=\"cit-pageRange\">, 1254\u20131255<\/span>.<\/p>\n<p><strong>230.\u00a0<\/strong>Zhou, X. and <strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cSynthesis of Novel Substituted N-heterocycles and Their Use of Selective Poly(ADP-ribose) Polymerase 1 (PARP1) Inhibitors\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>, 2025, accepted.<\/p>\n<p><strong>229. <u>Liang, S. H.<\/u><\/strong>\u00a0\u201cNovel Heterocyclic 5H-dibenzo[b,f]azepine Derivatives as Selective HDAC6 inhibitors for Treatment of Charcot Marie Tooth Disease\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>,\u00a0<span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 16<\/span><span class=\"cit-issue\">, 7<\/span><span class=\"cit-pageRange\">, 1245\u20131246<\/span>.<\/p>\n<p><strong>228. <u>Liang, S. H.<\/u><\/strong> \u201cNovel (1H-Pyrazol-4-ylamino)pyrimidine Derivatives as Wee1 Inhibitors for Treatment of Cancer\u201d, ACS Medicinal Chemistry Letters, 2025<span class=\"cit-volume\">, 16<\/span><span class=\"cit-issue\">, 7<\/span><span class=\"cit-pageRange\">, 1247\u20131248<\/span>.<\/p>\n<p><strong>227. <\/strong>Ran, W.; Hu, K.; Ye, W.; Zhang, L.; Chen, J.; Ji, B.; Mori, W.; Wang, Z.; Lu, H.; Haider, A.; Yamasaki, T.; Huang, H.; Xie, L.; Yang, Q.; Yuan, S.; Wang, X.; Gong, J.; Wang, H.; <strong><u>Liang, S. H.<\/u><\/strong>; Wang, J.; Wang, R.; Zhang, M. R. and Wang, L. &#8220;Radiofluorination of 2-Arylquinolin-4-yl Oxypropanamide Derivatives for TSPO Imaging in Neuroinflammatory Murine, Nonhuman Primates, and Human Brain Autoradiography with Insensitivity to the rs6971 Polymorphism&#8221;, <em data-start=\"489\" data-end=\"521\">Journal of Medicinal Chemistry<\/em>, 2025<span class=\"cit-volume\">, 68<\/span><span class=\"cit-issue\">, 12<\/span><span class=\"cit-pageRange\">, 12457\u201312472<\/span>. https:\/\/pubmed.ncbi.nlm.nih.gov\/40489695\/<\/p>\n<p><strong>226. <\/strong>Zhou, X.; Chen, J.; Patel, J. S.; Ran, W.; Li, Y.; Van, R. S.; Ibrahim, M. M. H.; Zhao, C.; Gao, Y.; Rong, J.; Chaudhary, A. F.; Li, G.; Hu, J.; Davenport, A. T.; Daunais, J. B.; Shao, Y.; Ran, C.; Collier, T. L.; Haider, A.; Schuster, D. M.; Levey, A.; Wang, L.; Corfas, G.; <strong><u>Liang, S. H<\/u><\/strong><u>.<\/u> &#8220;Imaging poly(ADP-ribose) polymerase-1 (PARP1) in vivo with 18F-labeled brain penetrant positron emission tomography (PET) ligand&#8221;, <em>Acta Pharmaceutica Sinica B, <\/em>2025, 15, 10, 5036-5049. Link: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2211383525003260<\/p>\n<p><strong>225. <\/strong>Shao, T.; Gu, Z.; Liu, Y.; Wang, X.; Tang, C.; Chen, N.; Wang, M.; Liu, X.; Song, H.; Chen, S.; Li, W.; Hui, H.; Jia, X.; Mao, H.; Chung, R. T.; <strong><u>Liang, S. H<\/u><\/strong><strong>.<\/strong>; Xiong, S. and Tian, J. &#8220;Long-term in vivo monitoring of transplanted mesenchymal stromal cells in colitis mice with magnetic particle imaging&#8221;, <em>EBioMedicine, <\/em>2025, 116, 105775. https:\/\/pubmed.ncbi.nlm.nih.gov\/40435720\/<\/p>\n<p><strong>224.\u00a0<\/strong>Song, Z. and <strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cNovel Tetrahydrocyclohepteneindole Derivatives Targeting Estrogen Receptor Alpha for the Treatment of Breast Cancer\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>,\u00a0<span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 16<\/span><span class=\"cit-issue\">, 6<\/span><span class=\"cit-pageRange\">, 967\u2013969<\/span>. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00283<\/p>\n<p><strong>223.\u00a0<\/strong>Hu, Q-L. and <strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cDeuterated 1,3 Dihydro-2H-indole-2-one Derivatives for Treatment of Depression or Anxiety\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>,\u00a0<span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 16<\/span><span class=\"cit-issue\">, 6<\/span><span class=\"cit-pageRange\">, 965\u2013966<\/span>. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00284<\/p>\n<p><strong>222.\u00a0<\/strong>Zhou, X. and <strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cSynthesis and Application of Novel Arginine Vasopressin Receptor 1A (AVPR1A) Antagonists\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>,\u00a0<span class=\"cit-year-info\">2025<\/span><span class=\"cit-volume\">, 16<\/span><span class=\"cit-issue\">, 6<\/span><span class=\"cit-pageRange\">, 963\u2013964<\/span>. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00285<\/p>\n<p><strong>221.\u00a0<\/strong>Rong, J. and <strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u201cNovel 2,6,9-Trisubstituted Purines as CDK2 Inhibitors for Treating Cancers\u201d,\u00a0<em>ACS Medicinal Chemistry Letters<\/em>, 2025,\u00a0<span class=\"cit-volume\">16<\/span><span class=\"cit-issue\">, 6<\/span><span class=\"cit-pageRange\">, 970\u2013971<\/span>. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00282<\/p>\n<p><strong>220. <\/strong>Liang, J.; Weng, S.; Zhang, J.; Jiang, S.; Li, W.; Li, S.; Rong, J.; Liu, H.; Chen, H.; Liu, Z.; Peng, H.; Yan, S.; Zhang, R.; <strong><u>Liang, S. H. <\/u><\/strong>and Zhang, L. &#8220;Diagnostic performance of [18F]FAPI-04 PET\/CT in suspected recurrent hepatocellular carcinoma: prospective comparison with contrast-enhanced CT\/MRI&#8221;, <em>European Journal of Nuclear Medicine and Molecular Imaging<\/em>, <em>2025, 52, 3951\u20133962<\/em>.\u00a0Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/40232335\/<\/p>\n<p><strong>219.\u00a0<\/strong>Dong, C.; Ye, W.; Xu, Y.; Chen, J.; Liao, K.; Wei, H.; Jiang, Y.; Hou, L.; Wei, J.; Tan, Z.; Song, Z.; Li, Y.; Haider, A.; Yuan, H.;\u00a0<strong><u>Liang, S. H<\/u><\/strong>. and Wang, L. \u201cAutomatic synthesis of a phosphodiesterase 4B (PDE4B) radioligand and PET imaging in depression rodent models\u201d,\u00a0<em>American Journal of Nuclear Medicine and Molecular Imaging<\/em>, 2025, 15, 55-64. Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/40401108\/<\/p>\n<p><strong>218. <\/strong>Feng, S. and <strong><u>Liang, S. H<\/u><\/strong>. \u201cNovel Sulfonamide Derivatives as Nav1.5 Sodium Channel Blockers for Treating Atrial Fibrillation\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 748-749. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00192<\/p>\n<p><strong>217. <\/strong>Song, Z. and <strong><u>Liang, S. H<\/u><\/strong>. \u201cNovel Tetrahydrobenzo[b]pyrazolo[3,4-e][1,4]diazepine Compounds as Oxytocin Receptor Agonists for Treating Autism Spectrum Disorders\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 752-753. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00190<\/p>\n<p><strong>216. <\/strong>Li, Y. and <strong><u>Liang, S. H<\/u><\/strong>. \u201cNovel Nonpeptide as Oxytocin Receptor Agonist\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 750-751. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00191<\/p>\n<p><strong>215. <\/strong>Li, Y. and <strong><u>Liang, S. H<\/u><\/strong>. \u201cNovel Tricyclic Compounds as GSK3 Inhibitors\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 724-727. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00162<\/p>\n<p><strong>214. <\/strong>Li, Y. and <strong><u>Liang, S. H<\/u><\/strong>. \u201cNovel Heterocyclic Pyrimidine Derivatives as GSK3\u03b1 Inhibitors\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 721-723. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00159<\/p>\n<p><strong>213. <\/strong>Song, Z. and <strong><u>Liang, S. H<\/u><\/strong>. \u201cNovel Azaindole Compounds as Phosphodiesterase 4B Inhibitors for Treating Immune-Inflammatory Diseases or Disorders\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 717-718. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00158<\/p>\n<p><strong>212. <\/strong>Li, Y. and <strong><u>Liang, S. H<\/u><\/strong>. \u201cNovel 2-Pyrrolidone Derivatives as Negative Allosteric Modulators of GluN2B-Containing NMDA Receptors\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 719-720. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00157<\/p>\n<p><strong>211. <\/strong>Li, Y.; Yuan, H.and <strong><u>Liang, S. H.<\/u> &#8220;<\/strong>Advances in the Structural Basis of GluN2A-Selective Negative Allosteric Modulators&#8221;, <em>ACS Medicinal Chemistry Letters, <\/em>2025. ASAP. https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00226<\/p>\n<p><strong>210. <\/strong>Zhao, T. and <u><strong>Liang, S. H<\/strong>.<\/u> &#8220;PDE7 as a Precision Target: Bridging Disease Modulation and Potential PET Imaging for Translational Medicine&#8221;, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 711-714. DOI: 10.1021\/acsmedchemlett.5c00160<\/p>\n<p><strong>209.<\/strong>Li, C.; Hu, Q. and <u><strong>Liang, S. H<\/strong>.<\/u> &#8220;CAIX-targeted PET imaging agents based on acetazolamide small molecule for clear cell renal cell carcinoma&#8221;<em>, American Journal of Nuclear Medicine and Molecular Imaging<\/em>, 2025, 15, 37-43. Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/40124762\/<\/p>\n<p><strong>208. <\/strong>Zhao, T. and <u><strong>Liang, S. H<\/strong>. <\/u>\u201cMultivalent FAPI-based radiopharmaceuticals in PET\/CT: from cancer diagnostics to theranostics\u201d, <em>American Journal of Nuclear Medicine and Molecular Imaging<\/em>, 2025, 15, 82-86. Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/40401110\/<\/p>\n<p><strong>207. <\/strong>Zhou X. and <strong>Liang, S. H<\/strong>. \u201cPreparation of Substituted Heterocycles and Their Use as DNA Polymerase Theta (POLQ) Inhibitors\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 536-537. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00137<\/p>\n<p><strong>206. <\/strong>Zhao, T. and <strong><u>Liang, S. H<\/u><\/strong>. \u201cNovel Triazole-Substituted Imidazo[1,2-a]Pyrimidine Compounds as cGAS inhibitors\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 530-531. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00136<\/p>\n<p><strong>205. <\/strong>Hu, Q-L. and <strong><u>Liang, S. H<\/u><\/strong>. \u201cNovel Cyclic Peptides as Interleukin-23 Inhibitor for Treating Inflammatory Disorders\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 532-533. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00135<\/p>\n<p><strong>204. <\/strong>Rong J. and <strong><u>Liang, S. H<\/u><\/strong>. \u201cNovel Pyrazolo[1,5-a]pyrimidine-3,5-diamines as nSMase2 Inhibitors\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 534-535. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00134<\/p>\n<p><strong>203. <\/strong>Li, Y. and <strong><u>Liang, S. H<\/u><\/strong>. \u201c6-Aryl Isoindolin-1-ones: Novel mGluR2 Negative Allosteric Modulators\u201d, ACS Medicinal Chemistry Letters, 2025, 16, 512-513. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00106<\/p>\n<p><strong>202. <\/strong>Li, Y. and <u><strong>Liang, S. H<\/strong>.<\/u> \u201cNovel 6-Aryl isoindolin-1-one Derivatives as Negative Allosteric Modulators of Metabotropic Glutamate Receptor 2\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 510-511. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00107.<\/p>\n<p><strong>201. <\/strong>Zhao, T. and <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span> \u201cEnhancing the Stability of 211At Radiopharmaceuticals: Insights from Ortho-Substituent Strategies\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 504\u2013507. DOI: https:\/\/doi.org\/10.1021\/acsmedchemlett.5c00102<\/p>\n<p><strong>200.<\/strong> Bi, C.; Patel, J. S. and <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span> &#8220;Development of CD73 Inhibitors in Tumor Immunotherapy and Opportunities in Imaging and Combination Therapy&#8221;, <em>Journal of Medicinal Chemistry<\/em>, 2025, 68, 6860\u20136869. DOI: https:\/\/doi.org\/10.1021\/acs.jmedchem.4c02151<\/p>\n<p><strong>199.<\/strong> Rong, J.; Zhao, C.; Chaudhary, A. F.; Chen, J.; Zhou, X.; Zhang, K.; Song, Z.; Sun, Z.; Gao, Y.; Zhang, Z.; Feng, S.; Collier, T. L.; Yuan, H.; Patel, J. S.; Haider, A.; Li, Y. and <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong> <\/span>\u201cDevelopment of a Novel <sup>18<\/sup>F-Labeled Radioligand for Imaging Cholesterol 24-Hydroxylase with Positron Emission Tomography\u201d, <em>ACS Pharmacology &amp; Translational Science<\/em>, 2025, 8, 800\u2013807. DOI: https:\/\/pubs.acs.org\/doi\/10.1021\/acsptsci.4c00683<\/p>\n<p><strong>198.<\/strong> Rong, J.; Zhao, C.; Chaudhary, A. F.; Jones, E.; Van, R.; Song, Z.; Li, Y.; Chen, J.; Zhou, X.; Patel, J. S.; Gao, Y.; Sun, Z.; Feng, S.; Zhang, Z.; Collier, T. L.; Ran, C.; Haider, A.; Shao, Y.; Yuan, H. and <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong> <\/span>\u201cDevelopment of a Novel <sup>18<\/sup>F-Labeled Radioligand for Imaging Phosphodiesterase 7 with Positron Emission Tomography\u201d, <em>Molecular Pharmaceutics<\/em>, 2025, 22, 1657\u20131666. DOI: https:\/\/pubs.acs.org\/doi\/10.1021\/acs.molpharmaceut.4c01379<\/p>\n<p><strong>197.<\/strong> Pees, A.; Morrone, C. D.; Tong, J.; Rong, J.; Shao, T.; Wear, D.; <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span>; Yu, W. H.; Vasdev, N. \u201cSex- and age-specific sensitivities of the endocannabinoid system in Alzheimer&#8217;s disease revealed by PET imaging with [<sup>18<\/sup>F]FMPEP-<em>d<\/em><sub>2<\/sub> and [<sup>18<\/sup>F]MAGL-2102\u201d, <em>Theranostics<\/em>, 2025, 15, 3368-3385. Link: https:\/\/www.thno.org\/v15p3368.htm<\/p>\n<p><strong>196.<\/strong> Feng, S. and <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span> \u201cIdentification of Indazole- and Azaindazole-Substituted Cyclopentapyrroles as G2019S Leucine-Rich Repeat Kinase 2 Inhibitors for the Treatment of CNS Disorders\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 368\u2013370. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00045<\/p>\n<p><strong>195.<\/strong> Rong, J.; Zhao, C.; Chaudhary, A. F.; Ware, T.; Van, R. S.; Li, Y.; Leon, E. R. C.; Dang, V.; Chen, J.; Xiao, Z.; Zhou, X.; Zhang, W.; Bi, C.; Zhang, K.; Patel, J. S.; Shao, Y.; Ran, C.; Collin, L.; Haider, A.; Cravatt, B. F. and <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span> &#8220;<span class=\"fontstyle0\">Development of a novel <\/span><span class=\"fontstyle0\">18<\/span><span class=\"fontstyle0\">F-labeled reversiblebinding radioligand for imaging monoacylglycerol lipase with positron emission tomography<\/span>&#8220;, <em><span class=\"fontstyle0\">Acta Pharmaceutica Sinica B<\/span><\/em>, 2025, accepted.<\/p>\n<p><strong>194<\/strong><strong>.<\/strong> Li, Y.; Mori, W.; Chaudhary, A.; Zhao, C.; Yamasaki, T.; Zhang, Z.; Feng, S.; Ware, T.; Rong, J.; Fujinaga, M.; Chen, J.; Kumata, K.; Zhang, Y.; Hu, K.; Xie, L.; Zhou, X.; Song, Z.; Gao, Y.; Sun, Z.; Patel, J. S.; Zhai, C.; Yuan, K. Y.; Collier, T. L.; Ran, C.; Collin, L.; Haider, A.; Grether, U.; Wittwer, M. B.; Cravatt, B. F.; Zhang, M.-R. and <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong> <\/span>\u201cRadiosynthesis and Evaluation of Novel 18F Labeled PET Ligands for Imaging Monoacylglycerol Lipase\u201d, <em>European Journal of Medicinal Chemistry<\/em>, 2025, 117246.<\/p>\n<p><strong>193. <\/strong>Rong, J. and <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span> \u201cNovel 5,6-fused and 6,6-fused bicyclic compounds as 15-prostaglandin dehydrogenase modulators\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 366\u2013367. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00010.<\/p>\n<p><strong>192. <\/strong>Hu, Q.-L. and <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span> \u201cNovel Cyclic Peptides Inhibiting Tumor Necrosis Factor Receptor 1 Activity\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 363\u2013365. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00011.<\/p>\n<p><strong>191. <\/strong>Zhao, T. and <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span> &#8220;Novel Pyrimidinyl Sulfonamide Derivatives as GPR17 Modulators&#8221;, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 361\u2013362. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00012.<\/p>\n<p><strong>190. <\/strong>Xin, Z. and <strong><u>Liang, S. H.<\/u><\/strong> &#8220;Hydroquinazoline Derivatives as Novel Natriuretic Peptide Receptor 1 (NPR1) Activators&#8221;, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 358\u2013360. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsmedchemlett.5c00013.<\/p>\n<p><strong>189.<\/strong> Song, Z. and <strong><u>Liang, S. H.<\/u><\/strong> \u201cIdentification of Phosphodiesterase-7 Inhibitors with Spiro[[1,3]Oxazolo[5,4-f]Quinazoline-9,1\u2032-Cyclohexan]-7-One Scaffold for the Treatment of Chronic Fatigue\u201d, <em>ACS Medicinal Chemistry Letters, <\/em>2025, accepted.<\/p>\n<p><strong>188. <\/strong>Li, Y. and <strong><u>Liang, S. H.<\/u> <\/strong>\u201cNovel Piperazine Derivatives as Selective Antagonists of GluN2B-containing NMDARs under Acidic pH Conditions\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, , 16, 354\u2013355. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.5c00002<\/p>\n<p><strong>187. <\/strong>Tan, Z.; Nie, B.; Wu, H.; Li, B.; Shang, J.; Zhang, T.; Xiao, Z.; Dong, C.; Zeng, C.; Wu, B.; Hou, L.; Guo, B.; Cheng, Y.; Gong, J.; Ye, W.; Xu, L.; Li, Y.; Li, X.; <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span>; Shan, B.; Xu, H.; Wang, L. \u201cBrain development during the lifespan of cynomolgus monkeys\u201d, <em>NeuroImage<\/em>, 2025, 305, 120952. Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/39662788\/<\/p>\n<p><strong>186. <\/strong>Hu, Q.-L. and <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span> \u201cCyclic Peptides Targeting Granzyme B: Potential Applications as PET Imaging Agents\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 180\u2013181. Link: https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmedchemlett.4c00608<\/p>\n<p><strong>185.<\/strong> Zhao, T. and <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span> \u201cNovel Tricyclic KRAS Inhibitors for the Treatment of Cancer\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2025, 16, 178\u2013179. 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H.<\/strong><\/span>\u00a0 \u201cDevelopment of a Candidate 11C-Labeled Selective Phosphodiesterase 1 Radioligand for Positron Emission Tomography\u201d,\u00a0<em>ACS Omega<\/em>, 2024, 9(44):44154\u201344163. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acsomega.4c03214<\/p>\n<p><strong>178. <\/strong>Xiao, Z.; Li, Y.; Haider, A.; Pfister, S. K.; Rong, J.; Chen, J.; Zhao, C.; Zhou, X.; Song, Z.; Gao, Y.; Patel, J. S.; Collier, T. L.; Ran, C.; Zhai, C.; Yuan, H. and <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span> \u201cRadiosynthesis and Evaluation of a Novel <sup>18<\/sup>F\u2011Labeled Tracer for PET Imaging of Glycogen Synthase Kinase 3\u201d, <em>American Journal of Nuclear Medicine and Molecular Imaging<\/em>, 2024, 14 (5), 327-336.<\/p>\n<p><strong>177. <\/strong>Liao, K.; Chen, J.; Ma, J.; Dong, C.; Bi, C.; Gao, Y.; Jiang, Y.; Wang, T.; Wei, H.; Hou, L.; Hu, J.; Wei, J.; Zeng, C.; Li, Y.; Yan, S.; Xu, H.; <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span> and Wang, L. &#8220;Preclinical characterization of [18F]D2-LW223: an improved metabolically stable PET tracer for imaging the translocator protein 18 kDa (TSPO) in neuroinflammatory rodent models and non-human primates&#8221;, <em>Acta Pharmacologica Sinica<\/em>, 2025, 46, 393-403. 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H.<\/strong><\/span> \u201cPreclinical Evaluation of Azabenzimidazole-Based PET Radioligands for \u03b3-8 Dependent Transmembrane AMPA Receptor Regulatory Protein Imaging\u201d, <em>ChemBioChem<\/em>, 2024, <span class=\"cit\">25(6):e202300813<\/span>.\u00a0 Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/38227784\/<\/p>\n<p><strong>166.<\/strong> Ahmed, H.; Wang, Y.; Griffiths, W. J.; Levey, A. I.; Pikuleva, I.; <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span> and Haider, A. \u201cBrain Cholesterol and Alzheimer\u2019s Disease\u2013Challenges and Opportunities in Probe and Drug Development\u201d, <em>Brain<\/em>, 2024, <span class=\"cit\">147(5):1622-1635<\/span>. Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/38301270\/<\/p>\n<p><strong>165. <\/strong>Chen, Z.; Chen, J.; Wakana, M.; Yi, Y.; Rong, J.; Li, Y.; Leon, C. E.; Shao, T.; Song, Z.; Yamasaki, T.; Zhang, Y.; Josephson, L.; Van, R. 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M.; W\u00fcnsch, B.; Haider, A. \u201cSynthesis and Biological Evaluation of Enantiomerically Pure (R)- and (S)-[<sup>18<\/sup>F]OF-NB1 for Imaging the GluN2B Subunit-Containing NMDA receptors\u201d, <em>Journal of Medicinal Chemistry<\/em>, 2023, 66, 16018-16031. Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/37979148\/<\/p>\n<p><strong>159. <\/strong>Rong, J.; Yamasaki, T.; Li, Y.; Kumata, K.; Zhao, C.; Haider, A.; Chen, J.; Xiao, Z.; Fujinaga, M.; Hu, K.; Mori, W.; Zhang, Y.; Xie, L.; Zhou, X.; Collier, T. L.; Zhang, M.-R. and <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong> <\/span>\u201cDevelopment of Novel <sup>11<\/sup>C-Labeled Selective Orexin-2 Receptor Radioligands for Positron Emission Tomography Imaging\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2023, 14, 1419-1426. 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H.<\/strong><\/span> and Ametamey S.M. &#8220;Evaluation of [<sup>18<\/sup>F]RoSMA-18-d<sub>6<\/sub> as a CB2 PET Radioligand in Non-Human Primates&#8221;, <em>ACS Chemical Neuroscience<\/em>, 2023, 14, 3752-3760. Link: https:\/\/pubs.acs.org\/doi\/10.1021\/acschemneuro.3c00222<\/p>\n<p><strong>156. <\/strong>Li, W.; Qiao, Y.; Chen, J.; Li, Y.; Du, X.; <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span> and Fu, H. \u201cVisualizing Reactive Astrocytes: Positron Emission Tomography Imaging Ligands for Imidazoline-2 Binding Sites\u201d, <em>View<\/em>, 2023, 4: 23230037.\u00a0 Link: https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/VIW.20230037<\/p>\n<p><strong>155.<\/strong> Song, R., Zhang, J., Perszyk, R. E., Chad, R C., Tang, W., Kannan, V., Li, J., Xu, Y., Chen, J., Li, Y., <span style=\"text-decoration: underline\"><strong>Liang, S. H.<\/strong><\/span>, Traynelis, S. F., &amp; Yuan, H. 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H.<\/u><\/strong>, and Wang, G. &#8220;An efficient synthesis of 2-isoxazolines from \u03b1-haloketone oximes and dimethyl sulfonium salts&#8221;, <em>Tetrahedron Letters<\/em>, 2019, 60, 382-385.<\/p>\n<p><strong>85.<\/strong>\u00a0Lin, J-H., Deng, X., Xiao, J-C., and\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0&#8220;Recent advances in\u00a0<sup>18<\/sup>F-labeling of trifluoromethylthiolation&#8221;, in\u00a0<em>Frontiers of Organofluorine Chemistry<\/em>, World Scientific, Hackensack, NJ, 2020, 649-665. DOI: https:\/\/doi.org\/10.1142\/9781786347336_0014.<\/p>\n<p><strong>84.<\/strong>\u00a0Rong, J., Chen, Z., Vasdev, N. and\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0&#8220;Aryl-<sup>18<\/sup>F bond formation from nucleophilic [<sup>18<\/sup>F]fluoride&#8221;, in\u00a0<em>Frontiers of Organofluorine Chemistry<\/em>, World Scientific, Hackensack, NJ, 2019, page 617-648.<\/p>\n<p><strong>83.<\/strong>\u00a0Josephson, L., Stratman, N., Liu, Y., Qian, F.,\u00a0<strong><u>Liang, S. H.<\/u><\/strong>, Vasdev, N. and Patel, S.\u00a0 &#8220;The Binding of BF-227-Like Benzoxazoles to Human \u03b1-Synuclein and Amyloid \u03b2 Peptide Fibrils&#8221;, <em>Molecular Imaging<\/em>, 2018, 17:1536012118796297. DOI: https:\/\/pubmed.ncbi.nlm.nih.gov\/30213230\/<\/p>\n<p class=\"DataField11pt-Single\"><strong>82.<\/strong>\u00a0Fu, H., Chen, Z., Josephson, L., Li, Z. and\u00a0<strong><u>Liang, S. H.<\/u><\/strong> \u00a0 &#8220;Positron Emission Tomography (PET) Ligand Development for Ionotropic Glutamate Receptors: Challenges and Opportunities for Radiotracer Targeting N-methyl-D-aspartate (NMDA), alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) and Kainate Receptors&#8221;,\u00a0 <em>Journal of Medicinal Chemistry<\/em>, 2019, 62, 403-419. DOI:\u00a0https:\/\/pubmed.ncbi.nlm.nih.gov\/30110164\/.\u00a0\u00a0PMID: 30110164<\/p>\n<p class=\"DataField11pt-Single\"><strong>81.<\/strong><strong>\u00a0<\/strong>Chen, Z., Mori, W., Zhang, X., Yamasaki, T., Dunn, P. J., Zhang, G. W., Fu, H., Shao, T., Zhang, Y., Hatori, A., Ma, L., Fujinaga, M., Xie, L., Deng, X., Li, H., Yu, Q., Rong, J., Josephson, L., Ma, J., Shao, Y., Tomita, S., Zhang, M. R., and\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u00a0\u00a0\u00a0&#8220;Synthesis and preclinical evaluation of\u00a0<sup>11<\/sup>C-labeled 1,3-dihydro-2H-benzo[d]imidazol-2-ones for imaging studies towards \u03b38-dependent transmembrane AMPA receptor regulatory protein.&#8221;,\u00a0<em> European Journal of Medicinal Chemistry<\/em>, 2018, 157, 898-908. PMC article: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6245653\/<\/p>\n<p class=\"DataField11pt-Single\"><strong>80.<\/strong>\u00a0Cheng, S., Jacobson, O., Zhu, G., Chen, Z.,\u00a0<strong><u>Liang, S. H.<\/u><\/strong>, Tian, R., Yang, Z., Niu, G., Zhu, X and Chen, X.\u00a0 &#8220;PET imaging of EGFR expression using an\u00a0<sup>18<\/sup>F-labeled RNA aptamer.&#8221;, <em>European Journal of Nuclear Medicine and Molecular Imaging<\/em>, 2019, 46, 948-956.\u00a0\u00a0 Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/30069577\/<\/p>\n<p class=\"DataField11pt-Single\"><strong>79.<\/strong>\u00a0Zheng, C., Wang, Y., Xu, Y., Chen, Z., Chen, G., and\u00a0<strong><u>Liang, S. H.<\/u>\u00a0<\/strong>\u00a0 &#8220;Ru-Photoredox-Catalyzed Decarboxylative Oxygenation of Aliphatic Carboxylic Acids through N-(acyloxy)phthalimide&#8221;,\u00a0 <em>Organic Letters<\/em>, 2018, 20, 4824-4827.\u00a0 Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/30070856\/<\/p>\n<p class=\"DataField11pt-Single\"><strong>78.<\/strong> Deng, X.; Rong, J.; Wang, L.; Vasdev, N.; Zhang, L.; Josephson, L. and <strong><u>Liang, S. H.<\/u><\/strong>\u00a0 &#8220;Chemistry for Positron Emission Tomography: Recent Advances in\u00a0<sup>11<\/sup>C-,\u00a0<sup>18<\/sup>F-,\u00a0<sup>13<\/sup>N- and\u00a0<sup>15<\/sup>O-labeling Reactions&#8221;,\u00a0 <em><span dir=\"ltr\" role=\"presentation\">Angewandte Chemie International Edition<\/span><\/em>, 2018, 58, 2580-2605. DOI: https:\/\/pubmed.ncbi.nlm.nih.gov\/30054961\/<\/p>\n<p class=\"DataField11pt-Single\"><strong>77.<\/strong>\u00a0Rong, J. and <strong><span style=\"text-decoration: underline\">Liang, S. H.<\/span><\/strong> &#8220;Aliphatic [<sup>18<\/sup>F]Fluorination Chemistry for Positron Emission Tomography&#8221;, in\u00a0<i>Synthetic Organofluorine Chemistry<\/i>, Springer, Hu, J. &amp; Umemoto, T., Eds. Springer Singapore: Singapore, 2018; pp 1-14.<\/p>\n<p class=\"DataField11pt-Single\"><strong>76.<\/strong>\u00a0Yamasaki, T., Mori, W., Zhang, Y., Hatori, A., Fujinaga, M., Wakizaka, H., Kurihara, Y., Wang, L., Nengaki, N., Ohya, T.,\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0and Zhang, M-R. &#8220;First demonstration of in vivo mapping for regional brain monoacylglycerol lipase using PET with [<sup>11<\/sup>C]SAR127303&#8243;, <em>NeuroImage<\/em>, 2018, 176, 313-320.\u00a0 Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/29738910\/<\/p>\n<p class=\"DataField11pt-Single\"><strong>75.<\/strong>\u00a0Collier, T. L.; Dahl, K.; Stephenson, N. A.; Holland, J. P.; Riley, A.;\u00a0<strong><u>Liang, S. H.<\/u>\u00a0<\/strong>and Vasdev, N.\u00a0 &#8220;Recent applications of a single quadrupole mass spectrometer in\u00a0<sup>11<\/sup>C,\u00a0<sup>18<\/sup>F and radiometal chemistry&#8221;, <em>Journal of Fluorine Chemistry,<\/em> 2018, 210, 46-55. DOI:\u00a0https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S002211391730516X<\/p>\n<p class=\"DataField11pt-Single\"><strong>74.<\/strong>\u00a0Cheng, R.; Mori, W.; Ma, L.; Alhouayek, M.; Hatori, A.; Zhang, Y.; Ogasawara, D.; Yuan, G.; Chen, Z.; Zhang, X.; Shi, H.; Yamasaki, T.; Xie, L.; Kumata, K.; Fujinaga, M.; Nagai, Y.; Minamimoto, T.; Svensson, M.; Wang, L.; Du, Y.; Ondrechen, M.; Vasdev, N.; Cravatt, B. F.; Fowler, C.; Zhang, M-R. and\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0 &#8220;In vitro and in vivo evaluation of\u00a0<sup>11<\/sup>C-labeled azetidine-carboxylates for imaging monoacylglycerol lipase by PET imaging studies&#8221;,\u00a0 <em>Journal of Medicinal Chemistry<\/em>, 2018,<i>\u00a061,\u00a0<\/i>2278-2291.\u00a0 \u00a0 Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/29481079\/<\/p>\n<p class=\"DataField11pt-Single\"><strong>73.<\/strong>\u00a0Krishnan, H. S.; Bernard-Gauthier, V.; Placzek, M. S.; Dahl, K.; Narayanaswami, V.; Livni, E.; Chen, Z.; Yang, J.; Collier, T. L.; Ran, C.; Hooker, J. M.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0and Vasdev, N. \u201cMetal protein-attenuating compound for PET neuroimaging: synthesis and preclinical evaluation of [<sup>11<\/sup>C]PBT2\u201d, <em>Molecular Pharmaceutics<\/em>, 2018, 15, 695-702.\u00a0\u00a0 Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/29298483\/<\/p>\n<p><strong>72.<\/strong>\u00a0Collier, T. L.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Mann, J. J.; Vasdev, N. and Kumar, J. S. D. &#8220;Microfluidic radiosynthesis of [<sup>18<\/sup>F]FEMPT, a high affinity PET radiotracer for imaging serotonin receptors&#8221;, <em>Beilstein Journal of Organic Chemistry<\/em>, 2017, 13, 2922-2927. DOI: 10.3762\/bjoc.13.285<\/p>\n<p><strong>71.<\/strong>\u00a0Bernard-Gauthier, V.; Legage, M.; Waengler, B.; Bailey, J. A.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Perrin, D.; Vasdev, N. and Schirrmacher, R. &#8220;Recent advances in fluorine-18 radiochemistry: Focus on B-<sup>18<\/sup>F, Si-<sup>18<\/sup>F, Al-<sup>18<\/sup>F and C-<sup>18<\/sup>F radiofluorination via spirocyclic iodonium ylides&#8221;, <em>Journal of Nuclear Medicine<\/em>, 2018, 59, 568-572.\u00a0\u00a0 Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/29284673\/<\/p>\n<p><strong>70.<\/strong>\u00a0Zhang, X.; Kumata, K.; Yamasaki, T.; Cheng, R.; Hatori, A.; Ma, L.; Zhang, Y.; Wang, L.; Kang, H. J.; Sheffler, D. J.; Cosford, N. D. P.; Zhang, M-R &amp;\u00a0<strong><u>Liang, S. H.<\/u>\u00a0<\/strong>&#8220;Synthesis and Preliminary Studies of a Novel Negative Allosteric Modulator, 7-((2,5-Dioxopyrrolidin-1-yl)methyl)-4-(2-fluoro-4-[<sup>11<\/sup>C]methoxyphenyl) quinoline-2-carboxamide for Imaging of Metabotropic Glutamate Receptor 2&#8243;, <em>ACS Chemical Neuroscience<\/em>, 2017, <em>8<\/em>, 1937-1948.\u00a0 \u00a0 Link: https:\/\/pubmed.ncbi.nlm.nih.gov\/28565908\/<\/p>\n<p><strong>69.<\/strong>\u00a0Collier, T. L.; Maresca K. P.; Normandin, M. D.; Richardson, P.; McCarthy, T. J.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Waterhouse, R. N. &amp; Vasdev, N. &#8220;Brain Penetration of the ROS1\/ALK Inhibitor Lorlatinib Confirmed by PET&#8221;, <em>Molecular Imaging<\/em>, 2017, 16, DOI: 10.1177\/1536012117736669.<\/p>\n<p><strong>68.<\/strong>\u00a0Bernard-Gauthier, V.; Collier, T. L.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong> &amp; Vasdev, N. &#8220;Discovery of PET Radiopharmaceuticals at the Academia-Industry Interface&#8221;, <em>Drug Discovery Today: Technologies<\/em>, 2017, 25, 19-26.<\/p>\n<p><strong>67.<\/strong>\u00a0Ran, C.; Albrecht, D. S.; Bredella, M. A.; Yang, J.; Yang, J.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Cypress, A. M.; Loggia, M. L.; Atassi, N. &amp; Moore, A. &#8220;PET imaging of human brown adipose tissue with TSPO tracer [<sup>11<\/sup>C]PBR28&#8243;, <em>Molecular Imaging and Biology<\/em>, 2018, 20, 188-193.<\/p>\n<p><strong>66.<\/strong>\u00a0Yuan, G.; Jankins, T. C.; Patrick, C. G.; Philbrook, P.; Sears, O.; Hatfield, S.; Sitkovsky, M.; Vasdev, N.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Ondrechen, M. J.; Pollastri, M. P. &amp; Jones, G. B. &#8220;Fluorinated adenosine A2A receptor antagonists inspired by Preladenant as potential cancer immunotherapeutics&#8221;, <em>International Journal of Medicinal Chemistry<\/em>, 2017, article ID 4852537.<\/p>\n<p><strong>65.<\/strong>\u00a0Krishnan, H.; Ma, L.; Vasdev, N. &amp;\u00a0<strong><u>Liang S. H.<\/u><\/strong>\u00a0&#8220;<sup>18<\/sup>F-Labeling of Sensitive Biomolecules for Positron Emission Tomography&#8221;, <em>Chemistry \u2013 A European Journal<\/em>, 2017, <em>23,\u00a0<\/em>15553 &#8211; 15577<em>.<\/em><\/p>\n<p><strong>64.<\/strong>\u00a0Yang, J.; Yang, J.; Wang, L.; Moore, A.;\u00a0<u>Liang, S. H.<\/u>\u00a0&amp; Ran, C. &#8220;Synthesis-Free PET Imaging of Brown Adipose Tissue and TSPO via Combination of Disulfiram and\u00a0<sup>64<\/sup>CuCl<sub>2<\/sub>&#8220;, <em>Scientific Reports<\/em>, 2017, <em>7, 8298.<\/em><\/p>\n<p><strong>63.<\/strong>\u00a0Dahl, K.; Collier, T. L.; Cheng, R.; Zhang, X.; Sadovski, O.;\u00a0<strong><u>Liang, S. H.<\/u>\u00a0<\/strong>and Vasdev, N. &#8220;\u201cIn-Loop\u201d [<sup>11<\/sup>C]CO<sub>2<\/sub>-Fixation: Prototype and Proof-of-Concept&#8221;, <em>Journal of Labelled Compounds and Radiopharmaceuticals<\/em>, 2017, 61, 252-262.<\/p>\n<p><strong>62.<\/strong>\u00a0Collier, T. L.; Normandin, M. D.; Stephenson, N. A.; Livni, E.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Wooten, D. W.; Esfahani, S. A.; Stabin, M. G.; Mahmood, U.; Chen, J.; Wang, W.; Maresca, K.; Waterhouse, R. N.; El Fakhri, G.; Richardson, P. &amp; Vasdev, N. &#8220;Synthesis and preliminary PET imaging of\u00a0<sup>11<\/sup>C and\u00a0<sup>18<\/sup>F isotopologues of the ROS1\/ALK inhibitor lorlatinib&#8221;, <em>Nature Communications<\/em>, 2017, 8<em>,\u00a0<\/em>15761. DOI:\u00a0 10.1038\/ncomms15761<\/p>\n<p><strong>61.<\/strong>\u00a0Ma, L.; Placzek, M. S.; Hooker, J. M.; Vasdev, N. &amp;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0&#8220;[<sup>11<\/sup>C]Cyanation of arylboronic acids in aqueous solutions&#8221;, <em>Chemical Communications<\/em>, 2017, 53, 6597-6600.<\/p>\n<p><strong>60.<\/strong>\u00a0Wang, L.\uff1b Cheng, R.; Fujinaga, M.; Yang, J.; Zhang, Y.; Hatori, A.; Kumata, K.; Yang, J.; Vasdev, N.; Du, Y.; Ran, C.; Zhang, M-R. &amp;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0&#8220;A Facile Radiolabeling of [<sup>18<\/sup>F]FDPA via Spirocyclic Iodonium Ylides: Preliminary PET Imaging Studies in Preclinical Models of Neuroinflammation&#8221;, <em>Journal of Medicinal Chemistry,<\/em>\u00a02017<em>,\u00a0<\/em>60, 5222-5227.<\/p>\n<p><strong>59.<\/strong>\u00a0Zheng, J.; Cheng, R.; Lin, J-H.; Yu, D-H.; Ma, L.; Jia, L.; Zhang, L.; Wang, L.; Xiao, J-C. &amp;\u00a0<strong><u>Liang, S. H.<\/u>\u00a0<\/strong>\u201cAn unconventional mechanistic insight on SCF<sub>3<\/sub>\u00a0formation from difluorocarbene: Preparation of\u00a0<sup>18<\/sup>F-labeled \u03b1-SCF<sub>3<\/sub> carbonyl compounds\u201d, <em>Angewandte Chemie International Edition<\/em>, 2017, 56, 3196-3200.<\/p>\n<p><strong>58.<\/strong>\u00a0Hu, K.; Patnaik, D.; Collier, T. L.; Lee, K. N.; Gao, H.; Swoyer, M. R.; Rotstein, B. H.; Krishnan, H. S.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Wang, J.; Yan, Z.; Hooker, J. M.; Vasdev, N.; Haggarty, S. J. &amp; Ngai, M-Y. \u201cDevelopment of [<sup>18<\/sup>F]Maleimide-Based Glycogen Synthase Kinase-3b Ligands for Positron Emission Tomography Imaging\u201d, <em>ACS Medicinal Chemistry Letters<\/em>, 2017, 8, 287-292.<\/p>\n<p><strong>57.<\/strong>\u00a0Yuan, G.; Wang, F.; Stephenson, N. A.; Wang, L.; Rotstein, B. H.; Vasdev, N.; Tang, P. &amp;\u00a0<strong><u>Liang, S. H.<\/u>\u00a0<\/strong>&#8220;Metal-free\u00a0<sup>18<\/sup>F-labeling of aryl-CF<sub>2<\/sub>H via nucleophilic radiofluorination and oxidative C-H activation&#8221;, <em>Chemical Communications<\/em>, 2017, 53, 126-129.<\/p>\n<p><strong>56.<\/strong>\u00a0Yang, J.; Yang, J.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Xu, Y.; Moore, A. &amp; Ran. C.\u00a0\u00a0 &#8220;Imaging hydrogen peroxide in Alzheimer&#8217;s disease via cascade signal amplification&#8221;, <em>Scientific Reports<\/em>, 2016, 6, 35613.<\/p>\n<p><strong>55.<\/strong>\u00a0Yuan, Z.; Cheng, R.; Chen, P.; Liu, G. &amp;\u00a0<strong><u>Liang, S. H.<\/u>\u00a0<\/strong>\u00a0 &#8220;Efficient Pathway for the Preparation of Aryl(isoquinoline)iodonium(III) Salts and Synthesis of Radiofluorinated Isoquinolines&#8221;, <em>Angewandte Chemie International Edition<\/em>, 2016, 55, 11882-11886.<\/p>\n<p><strong>54.<\/strong>\u00a0Rotstein, B. H.; Placzek, M. S.; Krishnan, H. S.; Pekosak, A.; Collier, T. L.; Wang, C.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Burstein, E. S.; Hooker, J. M. &amp; Vasdev, N. &#8220;Preclinical PET neuroimaging of Preclinical PET neuroimaging of [<sup>11<\/sup>C]bexarotene&#8221;, <em>Molecular Imaging<\/em>, 2016, 15, 1-5.<\/p>\n<p><strong>53.<\/strong>\u00a0Yuan, G.;\u00a0 Jones, G. B.; Vasdev, N. &amp;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0\u00a0 &#8220;Radiosynthesis and preliminary PET evaluation of\u00a0<sup>18<\/sup>F-labeled 2-(1-(3-fluorophenyl)-2-oxo-5-(pyrimidin-2-yl)-1, 2-dihydropyridin-3-yl)benzonitrile for imaging AMPA receptors&#8221;, <em>Bioorganic &amp; Medicinal Chemistry Letters<\/em>, 2016, 26, 4857-4860.<\/p>\n<p><strong>52.<\/strong>\u00a0Shi, H.; Braun, A.; Wang, L.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>*; Vasdev, N* &amp; Ritter, T.*\u00a0\u00a0 &#8220;Practical Synthesis of\u00a0<sup>18<\/sup>F-Difluoromethylarenes from Aryl (Pseudo) Halides&#8221;, <em>Angewandte Chemie International Edition<\/em>, 2016, 55, 10786-90.<\/p>\n<p><strong>51.<\/strong>\u00a0<strong><u>Liang, S. H.<\/u><\/strong>;\u00a0 Chen, M. J.; Normandin, M. D.; Chang, J. S.; Chang, G. C.; Taylor, C. K.; Trapa, P.; Plummer, M. S.; Para, K. S.; Conn, E. L.; Lopresti-Morrow, L.; Lanyon, L. F.; Cook, J. M.; Richter, K. E. G.; Nolan, C. E.; Schachter, J. B.; Janat, F.; Che, Y.; Shanmugasundaram, V.; Lefker, B. A.; Enerson, B. E.; Livni, E.; Wang, L.; Guehl, N.; Patnaik, D.; Wagner, F. F.; Perlis, R.; Holson, E. B.; Haggarty, S. J.; El Fakhri, G.; Kurumbail, R. G. &amp; Vasdev, N.\u00a0 &#8220;Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) that Modulates Tau Phosphorylation in Brain: Translation for PET Neuroimaging&#8221;, <em>Angewandte Chemie International Edition<\/em>, 2016, 55, 9601-5.<\/p>\n<p><strong>50.<\/strong>\u00a0Rotstein, B. H.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Placzek, M. S.; Hooker, J. M.; Gee, A. D.; Doll\u00e9, F.; Wilson, A. A. &amp; Vasdev, N.\u00a0 &#8220;11C=O Bonds Made Easily for Positron Emission Tomography Radiopharmaceuticals&#8221;, <em>Chemical Society Reviews<\/em>, 2016, 45, 4708-26.<\/p>\n<p><strong>49.<\/strong>\u00a0Rotstein, B. H.; Wang, L.; Liu, R. Y.; Patteson, J.; Kwan, E. E.; Vasdev, N. &amp;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0 &#8220;Mechanistic Studies and Radiofluorination of Structurally Diverse Pharmaceuticals with Spirocyclic Iodonium(III) Ylides&#8221;, <em>Chemical Science<\/em>, 2016, 7, 4407 &#8211; 4417.\u00a0<\/p>\n<p><strong>48.<\/strong>\u00a0Wang, L.; Mori, W.; Cheng, R.; Yui, J.; Hatori, A.; Ma, L.; Zhang, Y.; Rotstein, B. H.; Fujinaga, M.; Shimoda, Y.; Yamasaki, T.; Xie, L.; Nagai, Y.; Minamimoto, T.; Higuchu, M.; Vasdev, N.; Zhang, M.-R. &amp;\u00a0<strong><u>Liang, S. H.<\/u><\/strong> \u00a0\u00a0 &#8220;Synthesis and Preclinical Evaluation of Sulfonamido-based [11C-Carbonyl]-Carbamates and Ureas for Imaging Monoacylglycerol Lipase&#8221;, <em>Theranostics<\/em>,\u00a0 2016, 6, 1145-1159.<\/p>\n<p><strong>47.<\/strong>\u00a0Rashidian, M.; Wang, L.; Eden, J. G.; Jacobsen, J.; Hossain, I.; Wang, Q.; Victoria, G. D.; Vasdev, N.; Ploegh, H. &amp;\u00a0<strong><u>Liang, S. H.<\/u>\u00a0<\/strong> \u00a0 &#8220;Enzyme-Mediated Modification of Single Domain Antibodies for Imaging Modalities with different Characteristics&#8221;, <em>Angewandte Chemie International Edition<\/em>, 2016, 55, 528-533.\u00a0<\/p>\n<p><strong>46.<\/strong>\u00a0Wang, L.; Yui, J.; Wang, Q.; Zhang, Y.; Mori, W.; Shimoda, Y.; Fujinaga, M.; Kumata, K.; Yamasaki, T.; Hatori, A.; Rotstein, B. H.; Collier, T. L.; Ran, C.; Vasdev, N.; Zhang, M. -R. &amp;\u00a0<strong><u>Liang, S. H.<\/u>\u00a0<\/strong> \u00a0 &#8220;Synthesis and Preliminary PET Imaging Studies of a FAAH Radiotracer ([11C]MPPO) Based on alpha-Ketoheterocyclic Scaffold&#8221;, <em>ACS Chemical Neuroscience<\/em>, 2016, 7, 109-18.\u00a0<\/p>\n<p><strong>45.<\/strong>\u00a0Kassenbrock, A.; Vasdev, N. &amp;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0 &#8220;Selected PET Radioligands for Ion Channel Linked Neuroreceptor Imaging: Focus on GABA, NMDA and nACh Receptors&#8221;, <em>Current Topics in Medicinal Chemistry<\/em>, 2016, 16, 1830-42.<\/p>\n<p><strong>44.<\/strong>\u00a0Wang, L.; Jacobsen, O.; Avdic, D.; Rotstein, B. H.; Weiss, I. D.; Collier, L.; Chen, X.; Vasdev, N. &amp;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0&#8220;Ortho-stabilized\u00a0<sup>18<\/sup>F-azido click agents and application in PET imaging of single-stranded DNA aptamer&#8221;, <em>Angewandte Chemie International Edition<\/em>, 2015, 54, 12777-81.<\/p>\n<p><strong>43.<\/strong>\u00a0Zheng, J.; Wang, L.; Lin, J.-H.; Xiao, J.-C. &amp;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0&#8220;Difluorocarbene-derived Trifluoromethylthiolation and [<sup>18<\/sup>F]Trifluoromethylthiolation of Aliphatic Electrophiles&#8221;,<em> Angewandte Chemie International Edition<\/em>, 2015, 54, 13236-40.<\/p>\n<p><strong>42.<\/strong>\u00a0Jacobson, O.; Weiss, I.; Wang, L.; Wang, Z.; Yang, X.; Dewhurst, A.; Ma, Y.; Zhu, G.; Niu, G.; Kiesewetter, D. O.; Vasdev, N.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>* &amp; Chen, X.*\u00a0\u00a0 &#8220;<sup>18<\/sup>F-labeled Single-Stranded DNA Aptamer for PET Imaging of Protein Tyrosine Kinase-7 Expression&#8221;, <em>Journal of Nuclear Medicine<\/em>, 2015, 56, 1780-5.<\/p>\n<p><strong>41.<\/strong>\u00a0Stephenson, N. A.; Holland, J. P.; Kassenbrock, A.; Yokell, D. L.; Livni, E.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0&amp; Vasdev, N. &#8220;Iodonium Ylide\u2013Mediated Radiofluorination of\u00a0<sup>18<\/sup>F-FPEB and Validation for Human Use&#8221;, <em>Journal of Nuclear Medicine<\/em>, 2015, 56, 489-92.<\/p>\n<p><strong>40.<\/strong>\u00a0Calderwood, S.; Collier, T. L.; Gouverneur, V.;\u00a0<u><strong>Liang, S. H.<\/strong>*<\/u>\u00a0&amp; Vasdev, N.* &#8220;Synthesis of\u00a0<sup>18<\/sup>F-arenes from spirocyclic iodonium(III) ylides via continuous-flow microfluidics&#8221;, <em>Journal of Fluorine Chemistry<\/em>, 2015, 178, 249-253.<\/p>\n<p><strong>39.<\/strong>\u00a0<strong><u>Liang, S. H.<\/u><\/strong> &amp; Vasdev, N. &#8220;Total Radiosynthesis: Thinking Outside &#8216;the Box'&#8221;, <em>Australian Journal of Chemistry<\/em>, 2015, 68, 1319-28.<\/p>\n<p><strong>38.<\/strong>\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Southon, A. G.; Fraser, B. H.; Krause-Heuer, A. M.; Zhang, B.; Shoup, T. M.; Lewis, R.; Volitakis, I.; Han, Y.; Greguric, I.; Bush, A. I. &amp; Vasdev, N. &#8220;Novel Fluorinated 8-Hydroxyquinoline Based Metal Ionophores for Exploring the Metal Hypothesis of Alzheimer\u2019s Disease&#8221;, <em>ACS Medicinal Chemistry Letters<\/em>, 2015, 6, 1025-9.\u00a0<\/p>\n<p><strong>37.<\/strong>\u00a0Feng, M.; Tang, B.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>* &amp; Jiang, X.* &#8220;Sulfur Containing Scaffolds in Drugs: Synthesis and Application in Medicinal Chemistry&#8221;, <em>Current Topics in Medicinal Chemistry<\/em>, 2015, 15, 15.\u00a0<\/p>\n<p><strong>36.<\/strong>\u00a0Ren, W.; Xu, M.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Xiang, H.; Tang, L.; Zhang, M.; Ding, D.; Li, X.; Zhang, H. &amp; Hu, Y. &#8220;Discovery of a novel fluorescent probe for the sensitive detection of \u03b2-amyloid Deposits&#8221;, <em>Biosensors and Bioelectronics<\/em>, 2015, 75, 136-141.<\/p>\n<p><strong>35.<\/strong>\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Holland, J. P.; Stephenson, N. A.; Kassenbrock, A.; Rotstein, B. H.; Daignault, C. P.; Lewis, R.; Collier, L.; Hooker, J. M. &amp; Vasdev, N. &#8220;PET Neuroimaging Studies of [<sup>18<\/sup>F]CABS13 in a Double Transgenic Mouse Model of Alzheimer\u2019s Disease and Nonhuman Primates&#8221;, <em>ACS Chemical Neuroscience<\/em>, 2015, 6, 535-41.<\/p>\n<p><strong>34.<\/strong>\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Yokell, D. L.; Jackson, R. N.; Rice, P. A.; Livni, E.; Alagille, D.; Tamagnan, G.; Collier, T. L. &amp; Vasdev, N., Synthesis of 3-[<sup>18<\/sup>F]fluoro-5-(2-pyridinylethynyl)benzonitrile ([<sup>18<\/sup>F]FPEB). In\u00a0Radiochemical Syntheses, Vol 2: Further Radiopharmaceuticals for Positron Emission Tomography and New Strategies for Their Production, Scott, P. J. H., Ed. John Wiley &amp; Sons, Inc.: Hoboken, New Jersey, 2015; Vol. 2, pp 41-51.<\/p>\n<p><strong>33.<\/strong>\u00a0Rotstein, B. H.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Belov, V. V.; Livni, E.; Levine, D. B.; Bonab, A. A.; Papisov, M. I.; Perlis, R. H. &amp; Vasdev, N. &#8220;Practical Radiosynthesis and Preclinical Neuroimaging of [<sup>11<\/sup>C]isradipine, a Calcium Channel Antagonist&#8221;, <em>Molecules<\/em>, 2015, 20, 9550-9.\u00a0\u00a0<\/p>\n<p><strong>32.<\/strong>\u00a0Rotstein, B. H.; Stephenson, N. A.; Vasdev, N. &amp;\u00a0<strong><u>Liang, S. H.<\/u><\/strong> &#8220;Spirocyclic hypervalent iodine(III)-mediated radiofluorination of non-activated and hindered aromatics&#8221;, <em>Nature Communications<\/em>, 2014, 5, 4365.<\/p>\n<p><strong>31.<\/strong>\u00a0<strong><u>Liang, S. H.<\/u><\/strong>* &amp; Vasdev, N.* &#8220;C(sp<sup>3<\/sup>)-<sup>18<\/sup>F Bond Formation by Transition-Metal-Based [<sup>18<\/sup>F]Fluorination&#8221;, <em>Angewandte Chemie International Edition<\/em>, 2014, 53, 11416-8.<\/p>\n<p><strong>30.<\/strong>\u00a0Kasahara, T.; Jang, Y. J.; Racicot, L.; Panagopoulos, D.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong> &amp; Ciufolini, M. A. &#8220;Iodonium metathesis reactions&#8221;, <em>Angewandte Chemie International Edition<\/em>, 2014, 53, 9637-9.<\/p>\n<p><strong>29.<\/strong>\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Yokell, D. L.; Jackson, R. N.; Rice, P. A.; Callahan, R.; Johnson, K. A.; Alagille, D.; Tamagnan, G.; Collier, T. L. &amp; Vasdev, N. &#8220;Microfluidic continuous-flow radiosynthesis of [<sup>18<\/sup>F]FPEB suitable for human PET imaging&#8221;, <em>RSC Medicinal Chemistry<\/em>, 2014, 5, 432-5.<\/p>\n<p><strong>28.<\/strong>\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Yokell, D. L.; Normandin, M. D.; Rice, P. A.; Jackson, R. N.; Shoup, T. M.; Brady, T. J.; El Fakhri, G.; Collier, T. L. &amp; Vasdev, N. &#8220;First Human Use of a Radiopharmaceutical Prepared by Continuous-Flow Microfluidic Radiofluorination: Proof of Concept with the Tau Imaging Agent [<sup>18<\/sup>F]T807&#8243;, <em>Molecular Imaging<\/em>, 2014, 13, 1-5.<\/p>\n<p><strong>27.<\/strong>\u00a0Li, X.; Yang, C.; Wu, K.; Hu, Y.; Han, Y. &amp;\u00a0<strong><u>Liang, S. H.<\/u><\/strong> &#8220;A highly specific probe for sensing hydrogen sulfide in live cells based on copper-initiated fluorogen with aggregation-induced emission characteristics&#8221;, <em>Theranostics<\/em>, 2014, 4, 1233-8.<\/p>\n<p><strong>26.<\/strong>\u00a0Holland, J. P.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Rotstein, B. H.; Collier, T. L.; Stephenson, N. A.; Greguric, I. &amp; Vasdev, N. &#8220;Alternative approaches for PET radiotracer development in Alzheimer&#8217;s disease: imaging beyond plaque&#8221;, <em>Journal of Labelled Compounds and Radiopharmaceuticals<\/em>, 2014, 57, 323-31.<\/p>\n<p><strong>25.<\/strong>\u00a0Li, X.; Gong, Y.; Wu, K.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Cao, J.; Yang, B.; Y., H. &amp; Han, Y. &#8220;A highly sensitive and water soluble fluorescent probe for rapid detection of hydrogen sulfide in living cells&#8221;, <em>RSC Advances<\/em>, 2014, 4, 36106-9.\u00a0<\/p>\n<p><strong>24. <\/strong>Rotstein, B.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>\u00a0&amp; Vasdev, N. &#8220;Clinical PET Research Realized by [<sup>11<\/sup>C]CO<sub>2<\/sub>-Fixation&#8221; <em>Molecular Imaging Gateway<\/em> 2014, 8.<\/p>\n<p><strong>23.<\/strong>\u00a0Rotstein, B. H.; Hooker, J. M.; Woo, J.; Collier, T. L.; Brady, T. J.;\u00a0<u><strong>Liang, S. H.<\/strong>*<\/u>\u00a0&amp; Vasdev, N.* &#8220;Synthesis of [<sup>11<\/sup>C]Bexarotene by Cu-Mediated [<sup>11<\/sup>C]Carbon Dioxide Fixation and Preliminary PET Imaging&#8221;, <em>ACS Medicinal Chemistry Letters<\/em>, 2014, 5, 668-72.<\/p>\n<p><strong>22.<\/strong>\u00a0Rotstein, B. H.; Wey, H. Y.; Shoup, T. M.; Wilson, A. A.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Hooker, J. M. &amp; Vasdev, N. &#8220;PET Imaging of Fatty Acid Amide Hydrolase with [<sup>18<\/sup>F]DOPP in Nonhuman Primates&#8221;, <em>Molecular Pharmaceutics<\/em>, 2014, 11, 3832-8.<\/p>\n<p><strong>21.<\/strong>\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Collier, T. L.; Rotstein, B. H.; Lewis, R.; Steck, M. &amp; Vasdev, N. &#8220;Rapid microfluidic flow hydrogenation for reduction or deprotection of\u00a0<sup>18<\/sup>F-labeled compounds&#8221;, <em>Chemical Communications<\/em>, 2013, 49, 8755-7.<\/p>\n<p><strong>20.<\/strong>\u00a0Rotstein, B. H.;\u00a0<strong><u>Liang, S. H.<\/u><\/strong>; Holland, J. P.; Collier, T. L.; Hooker, J. M.; Wilson, A. A. &amp; Vasdev, N. &#8220;<sup>11<\/sup>CO<sub>2<\/sub> fixation: a renaissance in PET radiochemistry&#8221;, <em>Chemical Communications<\/em>, 2013, 49, 5621-9.<\/p>\n<p><strong>Selected publications (total 19) from doctoral and postdoctoral work<\/strong><\/p>\n<p><u>Liang, H.<\/u>; Hu, L.; Corey, E. J. &#8220;Di-tert-butylisobutylsilyl, another useful protecting group&#8221;, <em>Organic Letters,<\/em> 2011,\u00a013, 4120-3.<\/p>\n<p><u>Liang, H.<\/u>; Ciufolini, M. A. &#8220;Chiral hypervalent iodine reagents in asymmetric reactions&#8221;, <em>Angewandte Chemie International Edition<\/em>, 2011, 50, 11849-51.<\/p>\n<p><u>Liang, H.<\/u>; Ciufolini, M. A. &#8220;Oxidative Spirocyclization of Phenolic Sulfonamides: Scope and Applications&#8221;, <em>Chemistry \u2013 A European Journal<\/em>, 2010, 16, 13262-70.<\/p>\n<p><u>Liang, H.<\/u>; Ciufolini, M. A. &#8220;Tandem Phenolic Oxidative Amidation\u2212Intramolecular Diels\u2212Alder Reaction: An Approach to the Himandrine Core&#8221;, <em>Organic Letters<\/em>, 2010, 12, 1760-3.<\/p>\n<p><u>Liang, H.<\/u>; Ciufolini, M. A. &#8220;Improved Procedure for the Bimolecular Oxidative Amidation of Phenols&#8221;, <em>Journal of Organic Chemistry<\/em>, 2008, 73, 4299-301.<\/p>\n<p><u>Liang, H.<\/u>; Schul\u00e9, A.; Vors, J.-P.; Ciufolini, M. A. &#8220;An Avenue to the Sordarin Core Adaptable to Analog Synthesis&#8221;, <em>Organic Letters<\/em>, 2007, 9, 411922.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>280.\u00a0Liang, S. H.\u00a0\u201cFrom Lutetium to Terbium: A New Era in PSMA-Targeted Radioligand Therapy for mCRPC Patients\u201d,\u00a0American Journal of Nuclear Medicine and Molecular Imaging, 2025, 15, 219\u2013222. 279.\u00a0Liang, S. H.\u00a0\u201cPARP-Targeted Molecular Imaging for Noninvasive Diagnosis and Surgical Guidance in Basal Cell Carcinoma\u201d,\u00a0American Journal of Nuclear Medicine and Molecular Imaging, 2025, 15, <a class=\"more-link\" href=\"https:\/\/scholarblogs.emory.edu\/radiochem\/publications\/all-publications\/\">Read More &#8230;<\/a><\/p>\n","protected":false},"author":8331,"featured_media":0,"parent":10,"menu_order":-3000,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-245","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/pages\/245","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/users\/8331"}],"replies":[{"embeddable":true,"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/comments?post=245"}],"version-history":[{"count":234,"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/pages\/245\/revisions"}],"predecessor-version":[{"id":2552,"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/pages\/245\/revisions\/2552"}],"up":[{"embeddable":true,"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/pages\/10"}],"wp:attachment":[{"href":"https:\/\/scholarblogs.emory.edu\/radiochem\/wp-json\/wp\/v2\/media?parent=245"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}