98. Effect of Rhodium Carbenoid Structure on Cyclopropanation Chemoselectivity

Authors: Huw M.L. Davies, Stephen A. Panaro

Tetrahedron,

20005628, 4871-4880

 

Rhodium-stabilized carbenoids derived from aryldiazoacetates and vinyldiazoacetates undergo highly chemoselective intermolecular cyclopropanations, and this selectivity has been quantified by a Hammett study. These donor/acceptor substituted carbenoids are much more chemoselective than the traditional carbenoids derived from alkyl diazoacetates.

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