151. Direct Synthesis of (+)-Erogorgiaene through a Kinetic Enantiodifferentiating Step

Authors: Huw M. L. Davies, Abbas M. Walji

Angew. Chem. Int. Ed.

20054411, 1733-1735

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The combined approach of C–H activation and a Cope rearrangement catalyzed by a rhodium catalyst [Rh2(R-dosp)4] (dosp=(N-dodecylbenzenesulfonyl)prolinate) is shown to be a very effective method for the construction of the three stereogenic centers (marked in red, see scheme) present in the diterpene erogorgiaene (1).

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