Total Synthesis

The total synthesis of natural products provides the ultimate test for novel methodologies, taking it from a model system and proving its effectiveness in complex systems. The completion of a number of formal and total syntheses have showcased our chemistry and we maintain an active total synthesis program.

Medicinal Chemistry

An integral part of our research program is the application of our asymmetric methodologies to the preparation and exploration of novel pharmaceutical targets. We have established strong collaborations with groups who specialize in a variety of disease states, providing the opportunity to assess the biological activity of the broad range of analogues accessible through our modular approach.