Publications

Li, J. M, Lee, S., Zafar, R., Shin, E., and Choi, I. (2021) Sodium bicarbonate transporter NBCe1 regulates proliferation and viability of human prostate cancer cells LNCaP and PC3. Oncology Reports, 46:129. doi: 10.3892/or.2021.8080

Choi, I., Beedholm, K., Dam, V. S., Bae, S-H., Noble, D. J., Garraway, S. M., Aalkjaer, C., and Boedtkjer, E. (2021) Sodium bicarbonate cotransporter NBCn1/Slc4a7 affects locomotor activity and hearing in mice. Behavioural Brain Research, 401:113065. doi: 10.1016/j.bbr.2020.113065.

Schank, J. R., Lee, S., Gonzalez-Islas, C. E., Nennig, S. E., Fulenwider, H. D., Chang, J, Li, J-M., Kim, Y., Jeffers, L. A., Chung, J., Lee, J-K., Jin, Z., Aalkjaer, C., Boedtkjer, E., and Choi, I. (2020) Neuronal Acidosis Potentiates Alcohol Consumption and Tolerance to Alcohol-induced Sedation in Mice. Scientific Reports, 10:11017. doi: 10.1038/s41598-020-67291-0.

Park, H., Gonzalez-Islas, C. E., Kang, Y., Li, J-M, and Choi, I. (2019) Deletion of the Na/HCO3 transporter NBCn1 protects hippocampal neurons from NMDA-induced seizures and neurotoxicity in mice. Scientific Reports, 9:15981, doi:10.1038/s41598-019-52413-0.

Khammy MM, Kim S, Bentzen BH, Lee S, Choi I, Aalkjaer C, Jepps TA. (2018)  4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances Kv 7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries. Br J Pharmacol.  Feb;175(3):501-516. doi: 10.1111/bph.14097. Epub 2018 Jan 5. BMID: 29156097

Lee S, Park J, Li JM, Li K, Choi I. (2017) Evidence for ammonium conductance in a mouse thick ascending limb cell line. Physiol Rep. Aug;5(16). pii: e13379. doi: 10.14814/phy2.13379. PMID: 28830978

Park HJ, Lee S, Ju E, Jones JA, Choi I. (2017) Alternative transcription of sodium/bicarbonate transporter SLC4A7 gene enhanced by single nucleotide polymorphisms. Physiol Genomics. Mar 1;49(3):167-176. doi: 10.1152/physiolgenomics.00112.2016. Epub 2017 Jan 13. PMID: 28087757

Choi I, Jones J, Chung J, Lee, J-K, Schank JR. (2016) Effects of NBCn1 deletion on behavioral actions of ethanol in mice. FASEB. Apr 1;30:1_supplement Ib768

Lee HJ, Kwon MH, Lee S, Hall RA, Yun CC, Choi I. (2014) Systematic family-wide analysis of sodium bicarbonate cotransporter NBCn1/SLC4A7 interactions with PDZ scaffold proteins Physiol Rep. May 20;2(5). pii: e12016. doi: 10.14814/phy2.12016. Print 2014 May 1.

Aalkjaer C, Boedtkjer E, Choi I, Lee S. (2014) Cation-coupled bicarbonate transporters. Compr Physiol. Oct;4(4):1605-37. doi: 10.1002/cphy.c130005. PMID: 25428855

Choi I. (2012) SLC4A transporters. Curr Top Membr. 70:77-103. doi: 10.1016/B978-0-12-394316-3.00003-X.

Lee S, Choi I. (2011) Sodium-bicarbonate cotransporter NBCn1/Slc4a7 inhibits NH4Cl-mediated inward current in Xenopus oocytes. Exp Physiol. Aug;96(8):745-55. doi: 10.1113/expphysiol.2011.057844. Epub 2011 May 13.

Lee HJ, Tantawy MN, Nam KT, Choi I, Peterson TE, Price RR. (2011) Evaluation of an intraperitoneal ovarian cancer syngeneic mouse model using 18F-FDG MicroPET imaging. Int J Gynecol Cancer. Jan;21(1):22-7. doi: 10.1097/IGC.0b013e3182021bda. PMID: 21321526

Lee HJ, Park HJ, Lee S, Kim YH, Choi I. (2011) The sodium-driven chloride/bicarbonate exchanger NDCBE in rat brain is upregulated by chronic metabolic acidosis. Brain Res.  Mar 4;1377:13-20. doi: 10.1016/j.brainres.2010.12.062. Epub 2010 Dec 30. PMID:21195699

Lee HJ, Joo M, Abdolrasulnia R, Young DG, Choi I, Ware LB, Blackwell TS, Christman BW. (2010) Peptidylarginine deiminase 2 suppresses inhibitory {kappa}B kinase activity in lipopolysaccharide-stimulated RAW 264.7 macrophages. J Biol Chem. Dec 17;285(51):39655-62. doi: 10.1074/jbc.M110.170290. Epub 2010 Oct 11. PMID: 20937835

Park HJ, Rajbhandari I, Yang HS, Lee S, Cucoranu D, Cooper DS, Klein JD, Sands JM, Choi I. (2010)Neuronal expression of sodium/bicarbonate cotransporter NBCn1 (SLC4A7) and its response to chronic metabolic acidosis.Am J Physiol Cell Physiol. May;298(5):C1018-28. doi: 10.1152/ajpcell.00492.2009. Epub 2010 Feb 10. PMID:20147654

Lee S, Lee HJ, Yang HS, Thornell IM, Bevensee MO, Choi I. (2010) Sodium-bicarbonate cotransporter NBCn1 in the kidney medullary thick ascending limb cell line is upregulated under acidic conditions and enhances ammonium transport.Exp Physiol. Sep;95(9):926-37. doi: 10.1113/expphysiol.2010.053967. Epub 2010 Jun 30. PMID:20591978

Yang HS, Cooper DS, Rajbhandari I, Park HJ, Lee S, Choi I. (2009) Inhibition of rat Na+(-)HCO3(-) cotransporter (NBCn1) function and expression by the alternative splice domain. Exp Physiol. Nov;94(11):1114-23. doi: 10.1113/expphysiol.2009.048603. Epub 2009 Jul 28. PMID:19638364

Yang HS, Kim E, Lee S, Park HJ, Cooper DS, Rajbhandari I, Choi I. (2009) Mutation of Aspartate 555 of the Sodium/Bicarbonate Transporter SLC4A4/NBCe1 Induces Chloride Transport. J Biol Chem. Jun 5;284(23):15970-9. doi: 10.1074/jbc.M109.001438. Epub 2009 Mar 31. PMID:19336397

Cooper DS, Yang HS, He P, Kim E, Rajbhandari I, Yun CC, Choi I. (2009) Sodium/bicarbonate cotransporter NBCn1/slc4a7 increases cytotoxicity in magnesium depletion in primary cultures of hippocampal neurons. Eur J Neurosci. Feb;29(3):437-46. doi: 10.1111/j.1460-9568.2008.06611.x. Epub 2008 Dec 19. PMID:19170751

Parker MD, Musa-Aziz R, Rojas JD, Choi I, Daly CM, Boron WF. (2008) Characterization of human SLC4A10 as an electroneutral Na/HCO3 cotransporter (NBCn2) with Cl- self-exchange activity. J Biol Chem. May 9;283(19):12777-88. doi: 10.1074/jbc.M707829200. Epub 2008 Mar 4. PMID:18319254

Cooper DS, Lee HJ, Yang HS, Kippen J, Yun CC, Choi I. The electroneutral sodium/bicarbonate cotransporter containing an amino terminal 123-amino-acid cassette is expressed predominantly in the heart. J Biomed Sci. 2006 Jul;13(4):593-5. Epub 2006 Mar 18. PMID:16547769