19. Novel entry to the tropane system by reaction of rhodium(II) acetate stabilized vinylcarbenoids with pyrroles

Authors: Huw M.L. Davies, Wendy B. Young, H.David Smith

Tetrahedron Lett., 

198930, 4653-4656


Rhodium(II) acetate catalyzed decomposition of vinyldiazomethanes in the presence of N-alkoxycarbonylpyrroles provides a direct entry to the skeleton of tropane alkaloids. Similar reactions with N-alkylpyrroles result in the formation of alkylation products.

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