130. Effect of HD-23, a potent long acting cocaine-analog, on cocaine self-administration in rats

Authors: David C. S. Roberts, Kelly R. Jungersmith, Rachel Phelan, Timothy M. Gregg, Huw M. L. Davies


2003167, 4, 386-392

“Agonist” therapy for drug addiction proposes that a long acting analog, with similar properties to the abused substance might serve as a useful therapeutic agent. HD-23 is a very long acting tropane analog that displays a neurochemical profile similar to cocaine.

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