135. Influence of a β-Alkoxy Substituent on the C–H Activation Chemistry of Alkyl Ethers

Authors: Huw M. L. Davies, Jaemoon Yang

Ad. Syn. Cat., 

2003345, 9-10, 1133-1138

C–H activation reactions of 1,2-dimethoxyethane and methyl tert-butyl ether with methyl aryldiazoacetates or styryldiazoacetate catalyzed by Rh2(S-DOSP)4 result in the formation of 2-aryl- or 2-styryl-substituted propanoic acids with asymmetric induction up to 95% ee.

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