Authors: Joshua S. Alford , Jillian E. Spangler , and Huw M. L. Davies
J. Am. Chem. Soc.,
2013, 135 (32), 11712–11715
A highly effective synthesis of 2,3-fused pyrroles from cyclic ketones has been achieved. The transformation includes a rhodium-catalyzed reaction of 4-alkenyl-1-sulfonyl-1,2,3-triazoles featuring an unusual 4π electrocyclization. The methodology was further extended to the synthesis of indoles using a one-pot reaction starting from 1-ethynylcyclohexenes.