- Journal Articles
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1:MacLean JN, Hochman S, Magnuson DS. Lamina VII neurons are rhythmically active during locomotor-like activity in the neonatal rat spinal cord. Neurosci Lett. 1995 Sep 1;197(1):9-12. PubMed PMID: 8545064.
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2:Hochman S, McCrea DA. Effects of chronic spinalization on ankle extensor motoneurons. III. Composite Ia EPSPs in motoneurons separated into motor unit types. J Neurophysiol. 1994 Apr;71(4):1480-90. PubMed PMID: 8035229.
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3:Hochman S, McCrea DA. Effects of chronic spinalization on ankle extensor motoneurons. II. Motoneuron electrical properties. J Neurophysiol. 1994 Apr;71(4):1468-79. PubMed PMID: 8035228.
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4:Hochman S, McCrea DA. Effects of chronic spinalization on ankle extensor motoneurons. I. Composite monosynaptic Ia EPSPs in four motoneuron pools. J Neurophysiol. 1994 Apr;71(4):1452-67. PubMed PMID: 8035227.
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5:Hochman S, Jordan LM, Schmidt BJ. TTX-resistant NMDA receptor-mediated voltage oscillations in mammalian lumbar motoneurons. J Neurophysiol. 1994 Nov;72(5):2559-62. PubMed PMID: 7884484.
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6:Hochman S, Fedirchuk B, Shefchyk SJ. Membrane electrical properties of external urethral and external anal sphincter somatic motoneurons in the decerebrate cat. Neurosci Lett. 1991 Jun 10;127(1):87-90. PubMed PMID: 1881623.
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7:Fedirchuk B, Hochman S, Shefchyk SJ. An intracellular study of perineal and hindlimb afferent inputs onto sphincter motoneurons in the decerebrate cat. Exp Brain Res. 1992;89(3):511-6. PubMed PMID: 1644116.
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8:Schmidt BJ, Hochman S, MacLean JN. NMDA receptor-mediated oscillatory properties: potential role in rhythm generation in the mammalian spinal cord. Ann N Y Acad Sci. 1998 Nov 16;860:189-202. Review. PubMed PMID: 9928312.
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9:Machacek DW, Hochman S. Noradrenaline unmasks novel self-reinforcing motor circuits within the mammalian spinal cord. J Neurosci. 2006 May 31;26(22):5920-8. PubMed PMID: 16738234; PubMed Central PMCID: PMC2680501.
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10:Clemens S, Rye D, Hochman S. Restless legs syndrome: revisiting the dopamine hypothesis from the spinal cord perspective.Neurology. 2006 Jul 11;67(1):125-30. Review. PubMed PMID: 16832090.
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11:Zhu H, Clemens S, Sawchuk M, Hochman S. Expression and distribution of all dopamine receptor subtypes (D(1)-D(5)) in the mouse lumbar spinal cord: a real-time polymerase chain reaction and non-autoradiographic in situ hybridization study.Neuroscience. 2007 Nov 23;149(4):885-97. Epub 2007 Sep 12. PubMed PMID: 17936519; PubMed Central PMCID: PMC2185067.
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12:Hochman S. Spinal cord. Curr Biol. 2007 Nov 20;17(22):R950-5. PubMed PMID: 18029245.
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13:Zhu H, Clemens S, Sawchuk M, Hochman S. Unaltered D1, D2, D4, and D5 dopamine receptor mRNA expression and distribution in the spinal cord of the D3 receptor knockout mouse. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2008 Nov;194(11):957-62. doi: 10.1007/s00359-008-0368-5. Epub 2008 Sep 17. PubMed PMID: 18797877; PubMed Central PMCID: PMC2705064.
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14:Hochman S. Depression of spinal sensory transmission during REM sleep: dopaminergic involvement and insights into restless legs syndrome. Focus on “state-dependent changes in glutamate, glycine, GABA, and dopamine levels in cat lumbar spinal cord”. J Neurophysiol. 2008 Aug;100(2):549-50. doi: 10.1152/jn.90510.2008. Epub 2008 May 21. PubMed PMID: 18497361.
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15:Zimmerman A, Hochman S. Heterogeneity of membrane properties in sympathetic preganglionic neurons of neonatal mice: evidence of four subpopulations in the intermediolateral nucleus. J Neurophysiol. 2010 Jan;103(1):490-8. doi:10.1152/jn.00622.2009. Epub 2009 Nov 18. PubMed PMID: 19923248; PubMed Central PMCID: PMC2807234.
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16:Guo L, Meacham KW, Hochman S, DeWeerth SP. A PDMS-based conical-well microelectrode array for surface stimulation and recording of neural tissues. IEEE Trans Biomed Eng. 2010 Oct;57(10):2485-94. doi: 10.1109/TBME.2010.2052617. Epub 2010 Jun 14. PubMed PMID: 20550983.
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17:Meacham KW, Guo L, Deweerth SP, Hochman S. Selective stimulation of the spinal cord surface using a stretchable microelectrode array. Front Neuroeng. 2011 Apr 21;4:5. doi: 10.3389/fneng.2011.00005. eCollection 2011. PubMed PMID: 21541256; PubMed Central PMCID: PMC3083715.
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18:Thorpe AJ, Clair A, Hochman S, Clemens S. Possible sites of therapeutic action in restless legs syndrome: focus on dopamine and α2δ ligands. Eur Neurol. 2011;66(1):18-29. doi: 10.1159/000328431. Epub 2011 Jun 28. Review. PubMed PMID: 21709418.
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19:Anitha M, Joseph I, Ding X, Torre ER, Sawchuk MA, Mwangi S, Hochman S, Sitaraman SV, Anania F, Srinivasan S.Characterization of fetal and postnatal enteric neuronal cell lines with improvement in intestinal neural function.Gastroenterology. 2008 May;134(5):1424-35. doi: 10.1053/j.gastro.2008.02.018. Epub 2008 Feb 14. PubMed PMID: 18471518; PubMed Central PMCID: PMC2612783.
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20:Wilkinson KA, Kloefkorn HE, Hochman S. Characterization of muscle spindle afferents in the adult mouse using an in vitro muscle-nerve preparation. PLoS One. 2012;7(6):e39140. doi: 10.1371/journal.pone.0039140. Epub 2012 Jun 20. PubMedPMID: 22745708; PubMed Central PMCID: PMC3380032.
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21:Franco JA, Kloefkorn HE, Hochman S, Wilkinson KA. An in vitro adult mouse muscle-nerve preparation for studying the firing properties of muscle afferents. J Vis Exp. 2014 Sep 24;(91):51948. doi: 10.3791/51948. PubMed PMID: 25285602.
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22:Cheng J, Nath A, Knudsen B, Hochman S, Geiger JD, Ma M, Magnuson DS. Neuronal excitatory properties of human immunodeficiency virus type 1 Tat protein. Neuroscience. 1998 Jan;82(1):97-106. PubMed PMID: 9483506.
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23:Namaka MP, Sawchuk M, MacDonald SC, Jordan LM, Hochman S. Neurogenesis in postnatal mouse dorsal root ganglia. Exp Neurol. 2001 Nov;172(1):60-9. PubMed PMID: 11681840.
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24:MacDonald SC, Simcoff R, Jordan LM, Dodd JG, Cheng KW, Hochman S. A population of oligodendrocytes derived from multipotent neural precursor cells expresses a cholinergic phenotype in culture and responds to ciliary neurotrophic factor. J Neurosci Res. 2002 May 1;68(3):255-64. PubMed PMID: 12111855.
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25:Song L, Nath A, Geiger JD, Moore A, Hochman S. Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site. J Neurovirol. 2003 Jun;9(3):399-403. PubMed PMID: 12775422.
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26:MacDonald SC, Hochman S. A variation of the tissue print technique for studying isolated spinal cord cells in situ. Neurosci Lett. 1997 Feb 21;223(2):85-8. PubMed PMID: 9089679.
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27:Garraway SM, Pockett S, Hochman S. Primary afferent-evoked synaptic plasticity in deep dorsal horn neurons from neonatal rat spinal cord in vitro. Neurosci Lett. 1997 Jul 11;230(1):61-4. PubMed PMID: 9259464.
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28:Hochman S, Garraway SM, Pockett S. Membrane properties of deep dorsal horn neurons from neonatal rat spinal cord in vitro.Brain Res. 1997 Sep 5;767(2):214-9. PubMed PMID: 9367250.
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29:MacLean JN, Schmidt BJ, Hochman S. NMDA receptor activation triggers voltage oscillations, plateau potentials and bursting in neonatal rat lumbar motoneurons in vitro. Eur J Neurosci. 1997 Dec;9(12):2702-11. PubMed PMID: 9517475.
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30:Parsley CP, Cheng KW, Song L, Hochman S. Thin slice CNS explants maintained on collagen-coated culture dishes. J Neurosci Methods. 1998 Mar 13;80(1):65-74. PubMed PMID: 9606051.
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31:Hochman S, Schmidt BJ. Whole cell recordings of lumbar motoneurons during locomotor-like activity in the in vitro neonatal rat spinal cord. J Neurophysiol. 1998 Feb;79(2):743-52. PubMed PMID: 9463437.
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32:Cina C, Hochman S. Diffuse distribution of sulforhodamine-labeled neurons during serotonin-evoked locomotion in the neonatal rat thoracolumbar spinal cord. J Comp Neurol. 2000 Aug 7;423(4):590-602. PubMed PMID: 10880990.
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33:Garraway SM, Hochman S. Pharmacological characterization of serotonin receptor subtypes modulating primary afferent input to deep dorsal horn neurons in the neonatal rat. Br J Pharmacol. 2001 Apr;132(8):1789-98. PubMed PMID: 11309251; PubMed Central PMCID: PMC1572723.
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34:Garraway SM, Hochman S. Serotonin increases the incidence of primary afferent-evoked long-term depression in rat deep dorsal horn neurons. J Neurophysiol. 2001 May;85(5):1864-72. PubMed PMID: 11353003.
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35:Garraway SM, Hochman S. Modulatory actions of serotonin, norepinephrine, dopamine, and acetylcholine in spinal cord deep dorsal horn neurons. J Neurophysiol. 2001 Nov;86(5):2183-94. PubMed PMID: 11698510.
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36:Machacek DW, Garraway SM, Shay BL, Hochman S. Serotonin 5-HT(2) receptor activation induces a long-lasting amplification of spinal reflex actions in the rat. J Physiol. 2001 Nov 15;537(Pt 1):201-7. PubMed PMID: 11711573; PubMed Central PMCID: PMC2278931.
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37:Shay BL, Hochman S. Serotonin alters multi-segmental convergence patterns in spinal cord deep dorsal horn and intermediate laminae neurons in an in vitro young rat preparation. Pain. 2002 Jan;95(1-2):7-14. PubMed PMID: 11790462.
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38:Cowley KC, Cina C, Schmidt BJ, Hochman S. The isolated rat spinal cord as an in vitro model to study the pharmacologic control of myoclonic-like activity. Adv Neurol. 2002;89:275-87. PubMed PMID: 11968454.
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39:MacDonald SC, Fleetwood IG, Hochman S, Dodd JG, Cheng GK, Jordan LM, Brownstone RM. Functional motor neurons differentiating from mouse multipotent spinal cord precursor cells in culture and after transplantation into transected sciatic nerve.J Neurosurg. 2003 May;98(5):1094-103. PubMed PMID: 12744371.
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40:Clemens S, Hochman S. Conversion of the modulatory actions of dopamine on spinal reflexes from depression to facilitation in D3 receptor knock-out mice. J Neurosci. 2004 Dec 15;24(50):11337-45. PubMed PMID: 15601940; PubMed Central PMCID: PMC2731231.
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41:Clemens S, Sawchuk MA, Hochman S. Reversal of the circadian expression of tyrosine-hydroxylase but not nitric oxide synthase levels in the spinal cord of dopamine D3 receptor knockout mice. Neuroscience. 2005;133(2):353-7. PubMed PMID: 15878801; PubMed Central PMCID: PMC2705059.
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42:Dougherty KJ, Sawchuk MA, Hochman S. Properties of mouse spinal lamina I GABAergic interneurons. J Neurophysiol. 2005 Nov;94(5):3221-7. Epub 2005 Jul 13. PubMed PMID: 16014799; PubMed Central PMCID: PMC2679181.
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43:Shay BL, Sawchuk M, Machacek DW, Hochman S. Serotonin 5-HT2 receptors induce a long-lasting facilitation of spinal reflexes independent of ionotropic receptor activity. J Neurophysiol. 2005 Oct;94(4):2867-77. Epub 2005 Jul 20. PubMed PMID: 16033939; PubMed Central PMCID: PMC2745843.
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44:Cui D, Dougherty KJ, Machacek DW, Sawchuk M, Hochman S, Baro DJ. Divergence between motoneurons: gene expression profiling provides a molecular characterization of functionally discrete somatic and autonomic motoneurons. Physiol Genomics. 2006 Feb 14;24(3):276-89. Epub 2005 Nov 29. PubMed PMID: 16317082; PubMed Central PMCID: PMC2724224.
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45:Meacham KW, Giuly RJ, Guo L, Hochman S, DeWeerth SP. A lithographically-patterned, elastic multi-electrode array for surface stimulation of the spinal cord. Biomed Microdevices. 2008 Apr;10(2):259-69. PubMed PMID: 17914674; PubMed Central PMCID: PMC2573864.
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46:Dougherty KJ, Hochman S. Spinal cord injury causes plasticity in a subpopulation of lamina I GABAergic interneurons. J Neurophysiol. 2008 Jul;100(1):212-23. doi: 10.1152/jn.01104.2007. Epub 2008 May 14. PubMed PMID: 18480373; PubMed Central PMCID: PMC2493476.
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47:Hayes HB, Chang YH, Hochman S. An in vitro spinal cord-hindlimb preparation for studying behaviorally relevant rat locomotor function. J Neurophysiol. 2009 Feb;101(2):1114-22. doi: 10.1152/jn.90523.2008. Epub 2008 Dec 10. PubMed PMID: 19073815; PubMed Central PMCID: PMC2657055.
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48:Hochman S, Gozal EA, Hayes HB, Anderson JT, DeWeerth SP, Chang YH. Enabling techniques for in vitro studies on mammalian spinal locomotor mechanisms. Front Biosci (Landmark Ed). 2012 Jun 1;17:2158-80. Review. PubMed PMID: 22652770.
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49:Dougherty KJ, Sawchuk MA, Hochman S. Phenotypic diversity and expression of GABAergic inhibitory interneurons during postnatal development in lumbar spinal cord of glutamic acid decarboxylase 67-green fluorescent protein mice. Neuroscience. 2009 Oct 20;163(3):909-19. doi: 10.1016/j.neuroscience.2009.06.055. Epub 2009 Jun 26. PubMed PMID: 19560523; PubMed Central PMCID: PMC2746868.
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50:Shreckengost J, Calvo J, Quevedo J, Hochman S. Bicuculline-sensitive primary afferent depolarization remains after greatly restricting synaptic transmission in the mammalian spinal cord. J Neurosci. 2010 Apr 14;30(15):5283-8. doi:10.1523/JNEUROSCI.3873-09.2010. PubMed PMID: 20392950.
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51:Hochman S, Shreckengost J, Kimura H, Quevedo J. Presynaptic inhibition of primary afferents by depolarization: observations supporting nontraditional mechanisms. Ann N Y Acad Sci. 2010 Jun;1198:140-52. doi: 10.1111/j.1749-6632.2010.05436.x. PubMed PMID: 20536928.
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52:Hochman S. Long-term patch recordings from adult spinal neurons herald new era of opportunity. J Neurophysiol. 2011 Dec;106(6):2794-5. doi: 10.1152/jn.00873.2011. Epub 2011 Sep 28. PubMed PMID: 21957222; PubMed Central PMCID: PMC3234096.
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53:Hayes HB, Chang YH, Hochman S. Stance-phase force on the opposite limb dictates swing-phase afferent presynaptic inhibition during locomotion. J Neurophysiol. 2012 Jun;107(11):3168-80. doi: 10.1152/jn.01134.2011. Epub 2012 Mar 21. PubMed PMID: 22442562; PubMed Central PMCID: PMC3378366.
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54:Zimmerman AL, Sawchuk M, Hochman S. Monoaminergic modulation of spinal viscero-sympathetic function in the neonatal mouse thoracic spinal cord. PLoS One. 2012;7(11):e47213. doi: 10.1371/journal.pone.0047213. Epub 2012 Nov 5. PubMed PMID: 23144807; PubMed Central PMCID: PMC3489886.
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55:Hochman S, Hayes HB, Speigel I, Chang YH. Force-sensitive afferents recruited during stance encode sensory depression in the contralateral swinging limb during locomotion. Ann N Y Acad Sci. 2013 Mar;1279:103-13. doi: 10.1111/nyas.12055. PubMed PMID: 23531008; PubMed Central PMCID: PMC3616510.
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56:García-Ramírez DL, Calvo JR, Hochman S, Quevedo JN. Serotonin, dopamine and noradrenaline adjust actions of myelinated afferents via modulation of presynaptic inhibition in the mouse spinal cord. PLoS One. 2014 Feb 28;9(2):e89999. doi: 10.1371/journal.pone.0089999. eCollection 2014. PubMed PMID: 24587177; PubMed Central PMCID: PMC3938568.
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57:Gozal EA, O’Neill BE, Sawchuk MA, Zhu H, Halder M, Chou CC, Hochman S. Anatomical and functional evidence for trace amines as unique modulators of locomotor function in the mammalian spinal cord. Front Neural Circuits. 2014 Nov 7;8:134. doi: 10.3389/fncir.2014.00134. eCollection 2014. PubMed PMID: 25426030; PubMed Central PMCID: PMC4224135.
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58:Hochman S, Jordan LM, MacDonald JF. N-methyl-D-aspartate receptor-mediated voltage oscillations in neurons surrounding the central canal in slices of rat spinal cord. J Neurophysiol. 1994 Aug;72(2):565-77. PubMed PMID: 7983519.