Authors: Ravisekhara P. Reddy , Gene H. Lee , and Huw M. L. Davies
Org. Lett.,
2006, 8 (16), 3437–3440
The dirhodium tetracarboxylate, Rh2(S-PTAD)4, derived from adamantylglycine, is a very effective chiral catalyst for carbenoid reactions. High asymmetric induction was obtained in Rh2(S-PTAD)4-catalyzed intramolecular C−H insertion (94% ee), intermolecular cyclopropanation (99% ee), and intermolecular C−H insertion (92% ee).