Authors: Brendan T. Parr, Prof. Huw M. L. Davies
Angew. Chem. Int. Ed.,
2013, 52, 38, 10044–10047
Take your pick… A practical method for the synthesis of structurally diverse rhodium vinylcarbenes from stable 1-sulfonyl-1,2,3-triazole precursors has been developed. The reaction is general for a broad range of 4-alkenyl triazoles and dienes, enabling the stereoselective synthesis of a variety of polycyclic imines, which are readily converted into amines or aldehydes in a one-pot process.