The Environmental Metabolomics and Exposomics Research Group at Emory

EMERGE GROUP

 

Welcome To EMERGE !

We are a team of exposure scientists and molecular epidemiologists dedicated to advancing the science of the human exposome. Led by Dr. Donghai Liang, our group aims to comprehensively characterize the human exposome, external and internal environmental exposures individuals experience across the life course, and uncover the molecular mechanisms underlying the complex health effects of environmental mixtures. Our current research focuses on ubiquitous environmental pollutants—including air pollution, persistent organic pollutants, and ubiquitous environmental toxicants—and their contributions to a wide range of health outcomes, from maternal and child health to cancer and Alzheimer’s disease. To investigate these links, we leverage advanced exposure assessment tools and high-throughput omics technologies, with particular emphasis on high-resolution metabolomics and multi-omics integration.

Through a series of independent panel and cohort studies, we have demonstrated the power of untargeted and semi-targeted metabolomics to identify exposure biomarkers, internal dose indicators, and early biological responses. These studies have identified key metabolic pathways and signatures associated with traffic-related air pollution and persistent pollutants, providing critical insight into the biological underpinnings of exposure-related diseases. More recently, our work has expanded to integrate multiple omics layers—including the epigenome, proteome, metabolome, lipidome, and microbiome—to holistically examine how exogenous exposures interact with endogenous biological systems. This systems-level, multi-omics approach holds promise for transforming our understanding of disease etiology and advancing precision environmental health.

Check out the “Research” and “Publication” pages to learn more about the ongoing research projects and recent publications from the Environmental Metabolomics Research Group at the Emory. We are actively recruiting motivated individuals to join our team and please click “Opportunity” to learn more about the potential research and training positions. For research collaboration and other inquiry, please use the “Contact Us” form or contact Dr. Donghai Liang directly.

Latest News
  • 09/16/2025→ Congratulations to Youran Tan for co-leading a recent publication on brain metabolomics in Alzheimer’s disease with Dr. Anke Huls, along with co-authors Dr. Zhenjiang Li and Dr. Donghai Liang! Learn more…
  • 09/10/2025→ Congratulations to Dr. Mengyuan Ren for a succesful oral presentation at the 2025 Metabolomics Association of North America (MANA) conference! Learn more…
  • 09/10/2025→ Congratulations to Youran Tan for a succesful oral presentation at the 2025 Metabolomics Association of North America (MANA) conference! Learn more…
  • 08/18/2025 to 08/20/2025 → Congratulations to all EMERGE members for successful presentations at the Joint Annual Meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology 2025! To learn more about the presentations please see Day 1, Day 2, Day 3.
  • 08/20/2025→ Congratulations to Dr. Mengyuan Ren for successfully co-hosting the symposium “Bridging Mixture Exposure to Human Reproducitve Health” at the joint ISES-ISEE 2025 conference! Learn more… 
  • 08/04/2025→ Congratulations to Dr. Mengyuan Ren and Youran Tan being selected as recipients of the 2025 the Metabolomics Association of North America (MANA) Early Career Member (ECM) Travel Awards!  Learn more… 
  • 07/24/2025→ Congratulations to Ziyin Tang, Dr. Jeremy Sarnat, Youran Tan, and Dr. Donghai Liang on publishing a proteomics study on the associations of air pollution mixture exposure with plasma proteins in an elderly U.S. panel at Environmental Science and Technology! Learn more… 
  • 06/26/2025→ Congratulations to Dr. Paula Nesbeth on being selected as an Early Career Members Network (EMN) Travel Award winner at the Metabolomics Society 2025 meeting!  Learn more…
  • 05/30/2025→ Congratulations to Youran Tan on receiving the Livingston Scholar award from Emory Rollins School of Public Health! 
  • 05/29/2025→ Congratulations to Drs. Zhenjiang Li and Jeremy Sarnat, Youran Tan, and Dr. Donghai Liang on publishing an innovative metabolomics study to unravel the molecular links between fine particulate matter exposure and early birth risks in the Atlanta African American Maternal-Child Cohort at Environmental Science and Technology! Learn more… Also check out the media reports by MSN newsthe New Lede, and the Emory News Center.
  • 05/10/2025→ Congratulations to Cathy Wang and Siddhi Desai on successfully obtaining their Master of Public Health degrees from Emory Rollins! 
  • 04/28/2025→ Congratulations to Cathy Wang on winning the ILE Excellence Award from the Gangarosa Department of Environmental Health!
  • 04/15/2025→ Congratulations to Drs. Donghai Liang and Mengyuan Ren on being recognized as the Top-Tier Peer Reviewers by Environmental Health Perspectives (EHP)! Learn more…
  • 04/03/2025→ Check out the media reports and interviews on our recent Nature Communications paper led by Dr. Susan Hoffman, including CNNUS NewsScience MagScience Daily, and the Emory News Center.
  • 04/02/2025→ Congratulations to Dr. Susan Hoffman, Ziyin Tang, Thompson Huynh, Dr. Kait Taibl, Youran Tan, and Dr. Donghai Liang on publishing a novel metabolomics study on the impact of prenatal phthalate exposure on newborn metabolome and infant neurodevelopment at Nature Communications!  Learn more…
  • 03/26/2025→ Congratulations to Dr. Susan Hoffman on successfully defending her PhD dissertation, entitled “Exploring Maternal Epigenomic and Metabolomic Influences on Gestational Age: Insights from Multi-Omics Integration and Mediation Analysis of PFAS Exposure” in the Epidemiology program! Learn more…
  • 02/21/2025→ Congratulations to Cathy Wang on receiving an offer from the Emory Environmental Health Science PhD program! 
  • 02/13/2025→ Congratulations to Dr. Kait Taibl on successfully defending her PhD dissertation, entitled “Molecular phenotyping of a PFAS mixture during human pregnancy with high-throughput, high-resolution, high-dimensional technologies” in the Environmental Health Science program! Learn more…
  • 02/01/2025→ Congratulations to Drs. Robert Hood and Donghai Liang as well as Yilin Wang and Youran Tan on publishing a metabolome-wide association study on the association between the pro-fertility diet and in vitro fertilization endpoints at the Journal of Nutrition! Learn more…
  • 12/18/2024→ Check out a recent interview with Dr. Donghai Liang by the Journal of Exposure Assessment, where Dr. Liang shared insights into the future of environmental exposure and health and his experience in addressing complex research challenges. Learn more…
  • 12/16/2024→ Congratulations to Ziyin Tang, Sabrina Chow, Drs. Jeremy Sarnat and Donghai Liang on publishing a large-scale metabolome-wide association study on ambient air pollution in the Cancer Prevention Study-II Nutrition Cohort at Environmental Science and Technology! Learn more…
  • 12/15/2024→ Congratulations to Susan Hoffman and Dr. Donghai Liang on publishing a recent study on the development of a metabolomic risk score for exposure to traffic-related air pollution at Environmental Research! Learn more…
  • 11/28/2024→ Congratulations to Ziyin Tang on receiving a scholarship from the Air & Waste Management Association Georgia Chapter! Learn more…
  • 11/26/2024→ Congratulations to Youran Tan and Haomin Li on successfully defending their dissertation proposals and they are now PhD candidates in the Emory Environmental Health Science program!
  • 11/08/2024→ Congratulations to Dr. Donghai Liang ln receiving a pilot grant funding to expand our ongoing investigations on applying cutting-edge exposomics and multi-Omics to assess impacts of air pollution exposures on lung cancer risk and the underlying biological mechanisms in the Cancer Prevention Study Cohorts from Winship Cancer Institute of Emory University and the American Cancer Society! Learn more… 
  • 11/06/2024→ Congratulations to Youran Tan, Kait Taibl, Che-Jung Chang, and Dr. Donghai Liang on publishing a prospective analysis of PFAS from early pregnancy to delivery in the Atlanta African American Maternal–Child Cohort, at Environmental Health Perspectives! Learn more…
  • 11/05/2024→ Congratulations to James (Jiada) Zhan and Dr. Donghai Liang on publishing Dietaryindex, a user-friendly and versatile R package for standardizing dietary pattern analysis, at the American Journal of Clinical Nutrition! Learn more…
  • 10/24/2024→ Congratulations to Youran Tan, Ziyin Tang, and Sabrina Chow on receiving the Conference Awards from the International Society of Exposure Science!
  • 10/15/2024→ Congratulations to Dr. Kasthuri Sivalogan on successfully defending her PhD dissertation, entitled “Maternal and environmental influences on child health in a multicountry household air pollution intervention trial” in the Emory Nutrition Health Science program!
  • 10/03/2024→ Congratulations to Susan Hoffman and Kaitlin Taibl on getting accepted to the prestigious CDC Epidemic Intelligence Service EIS Fellowship!
  • 09/20/2024→ Congratulations to Dr. Donghai Liang ‘s promotion to Associate Professor with Tenure at Emory Rollins School of Public Health! Learn more…
  • 09/15/2024→ Congratulations to Dr. Donghai Liang for receiving a major $4 million R01 Award (MPIs: Huels and Liang) from NIA! We will investigate the molecular connections underlying the neurotoxicity of air pollution using innovative cross-tissue approaches, with the overarching goal of providing key insights into the relationship between air pollution mixtures, biological response profiles, and Alzheimer’s disease and related dementias. Learn more…
  • 09/04/2024→ Congratulations to James (Jiada) Zhan on successfully defending his dissertation proposal and is now a PhD candidate in the Emory Nutrition Health Science program!
  • 08/16/2024Congratulations to Ziyin Tang for receiving the prestigious NCI F99/K00 award! Learn more
  • 08/15/2024Congratulations to Dr. Donghai Liang for receiving a major $11.4 million U01 Award (MPIs: Huels, Liang, and Wingo) from NIA! Teaming up with Drs. Anke Huels and Thomas Wingo, we will investigate the multi-omics perturbations associated with complex environmental toxicants and their contribution to Alzheimer’s Disease and Related Dementias!  Learn more…
  • 08/15/2024Congratulations to Kaitlin Taibl on publishing the 2nd chapter of her PhD dissertation at Free Radical Biology & Medicine! Learn more…
  • 07/31/2024Congratulations to Youran Tan, Drs. Jeremy Sarnat and Donghai Liang on publishing an important collaborative air pollution metabolomics study with the ECLIPSE team at Environmental Science & Technology! Learn more…
  • 07/26/2024Congratulations to Dr. Donghai Liang for receiving the prestigious Joan M. Daisey Outstanding Young Scientist Award from ISES! Learn more…
  • 06/24/2024Congratulations to Ziyin Tang, Sabrina Chow, Drs. Jeremy Sarnat and Donghai Liang on publishing an important collaborative lung cancer metabolomics study with collaborators from American Cancer Society at BMC Medicine! Learn more…
  • 05/14/2024Congratulations to Drs. Robert Hood and Donghai Liang on publishing a novel study linking phthalate exposures and live birth at Environmental Research! Learn more…
  • 05/04/2024Congratulations to Dr. Robert Hood and all EMERGE team members on publishing a Narrative Review on Metabolomics Application in Understanding the Link Between Air Pollution and Infant Health Outcomes  at Current Pollution Reports! Learn more…
  • 05/01/2024Congratulations to Kasthuri Sivalogan and Dr. Donghai Liang on publishing an Untargeted Metabolomics Analysis of Human Milk from Guatemalan Mothers at Current Developments in Nutrition! Learn more…
  • 04/23/2024Congratulations to Dr. Donghai Liang for receiving a major R01 Award (PI: Liang) from NIEHS! In the OMIT-PTB study, we will integrate longitudinal multi-omics data in epigenome, metabolome, and microbiome to comprehensively characterize the molecular connections between maternal exposures to traffic-related air pollution and preterm birth among 700 participants in the Atlanta African American Maternal-Child cohort. Learn more…
  • 04/12/2024Congratulations to Drs. Zhenjiang Li, Donghai Liang and Anke Huels on their recent publication being recognized as NIEHS Papers of the Month! Learn more…
  • 03/15/2024Congratulations to Kaitlin Taibl, Youran Tan, and Drs. Donghai Liang and Stephanie Eick on their recent publication on phthalate exposure and inflammation biomarkers during pregnancy at Science of the Total Environment! Learn more…
  • 02/12/2024Congratulations to Drs. Zhenjiang Li, Donghai Liang and Anke Huels on publishing a great study on Differential DNA methylation in the brain as potential mediator of the association between traffic-related fine particulate matter and markers of Alzheimer’s disease at Alzheimer’s & Dementia! Learn more…
  • 01/24/2024Congratulations to Dr. Donghai Liang and Youran Tan on publishing an ECHO-wide Metabolomics Study on Childhood BMI at Metabolomics! Learn more…
  • 01/10/2024Fantastic News! Our recent Nature Communication paper led by Kaitlin Taibl and Dr. Donghai Liang, was selected as one of Best environmental health studies of 2023 by NIEHS! Learn more…

More updates & news from previous years can be found here