Feistel D, Elmostafa R, and MA Hickman. Virulence phenotypes result from interactions between pathogen ploidy and genetic background. Ecology & Evolution; 2020;00:1–13. [link]

Smith AC and MA Hickman. Host-Induced Genome Instability Rapidly Generates Phenotypic Variation across Candida albicans Strains and Ploidy States. mSphere 5: e00433-20. [link]

Humphrey KM, Zhu L, Hickman MA, Hasan S, Maria H, Liu T, and LN Rusche. Evolution of distinct responses to low NAD+ stress by rewiring the Sir2 deacetylase network in yeasts. Genetics 214: 855-68. [link]


Avramovska O and MA Hickman. The magnitude of Candida albicans stress-induced genome instability results from an interaction between ploidy and antifungal drugs. G3; 9:4019-4027. [link]

Feistel D, Elmostafa R, Nguyen N, Penley M, Morran L and MA Hickman. A novel virulence phenotype rapidly assesses Candida fungal pathogenesis in healthy and immunocompromised Caenorhabditis elegans hosts. mSphere, 4:e00697-18. [link]


Gerstein AC, Lim H, Berman J, & MA Hickman. Ploidy tug-of-war: evolutionary and genetic environments influence the rate of ploidy drive in a human fungal pathogen. Evolution, 71: 1025-1038. [link]


Ciudad T, Hickman MA, Bellido A, Berman J, & G Larriba. The Phenotypic Consequences of a Spontaneous Loss of Heterozygosity in a Common Laboratory Strain of Candida albicans. Genetics, 203: 1161-1176. [link]


Hickman MA, Paulson C, Dudley A & J Berman. Parasexual ploidy reduction drives population heterogeneity through random and transient aneuploidy in Candida albicans. Genetics, 200: 781–794[link]

  • Press Coverage: Recommended in Faculty of 1000


Tsai HJ, Baller JA, Liachko I, Koren A, Burrack LS, Hickman MA Thevandavakkam MA, Rusche LN, Dunham MJ, & J Berman. Origin replication complex binding, nucleosome depletion patterns and a primary sequence motif can predict origins of replication in a genome with epigenetic centromeres. mBio, 5: e01703-14. [link]


Hickman MA, Zeng G, Forche A, Hirakawa MP, Abbey D, Harrison BD, Wang YM, Su CH, Bennett RB, Wang Y, & J Berman. The ‘obligate diploid’ Candida albicans forms mating-competent haploids. Nature, 494: 55-59. [link]

  • Press Coverage: Gow, N. (2013) Multiple mating strategies. Nature, 494: 45-46.
  • Recommended in Faculty of 1000


Abbey D, Hickman MA, Gresham D, & J Berman. High-Resolution SNP/CGH Microarrays Reveal the Accumulation of Loss of Heterozygosity in Commonly Used Candida albicans Strains. G3, 1: 523-530. [link]

Hickman MA, Froyd CA, & LN Rushe. Reinventing heterochromatin in budding yeasts: Sir2 and the origin recognition complex take center stage. Euk Cell, 10(9): 1183-92. [link]


Hickman MA & LN Rusche. Transcriptional silencing functions of the yeast protein Orc1/Sir3 subfunctionalized after gene duplication. PNAS, 107(45): 19384-9. [link]


Hickman MA & LN Rusche. The Sir2-Sum1 complex represses transcription using both promoter-specific and long-range mechanisms to regulate cell identity and sexual cycle in the yeast Kluyveromyces lactis. PLoS Genetics, 5: e1000710. [link]


Hickman MA & LN Rusche. Substitution as a Mechanism for Genetic Robustness: the Duplicated Deacetylases Hst1p and Sir2p in Saccharomyces cerevisiaePLoS Genetics, 3: e126. [link]

  • Press Coverage: Louis, EJ. (2007) Evolutionary genetics: Making the most of redundancy. Nature, 449: 673-674.

Hickman MA & LN Rusche. “Evolution of Silencing at the Mating-Type Loci in Hemiascomycetes” J. Heitman, JW Taylor, JW Kronstad and LA Casselton (eds) Sex in Fungi: Molecular Determination and Evolutionary Implications. ASM Press