“Radiochemistry for Positron Emission Tomography”, Nature Communications, 2023, 14, 3257. The concept translational radiochemistry is introduced herein to emphasize the unique characteristics of PET chemistry aimed at human translation and routine radiopharmaceutical production. To qualify any novel radiochemical method from benchtop discovery as translational radiochemistry, we evaluate it not Read More ...
“Assessment of cholesterol homeostasis in the living human brain”, Science Translational Medicine, 2022, 14(665), eadc9967. Back to Main Research Page
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Steven H. Liang began his professional career as a NSERC fellow under the mentorship of Professor EJ Corey at Harvard University in 2010. He started his junior faculty position (Assistant Professor 2013) at Massachusetts General Hospital and Harvard Medical School, then promoted to the Director of Radiochemistry (2017) and Associate Read More ...
Translational Radiochemistry Compared to diversity of synthetic organic chemistry methods, only limited radiochemical methods are available to introduce PET isotopes, including fluorine-18 (18F, t1/2=109.7 min) and carbon-11 (11C, t1/2=20.3 min). Therefore we strive to develop novel methods to radiolabel important molecules that were previously inaccessible, and hope to establish a general Read More ...
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