2019 Publications (since Associate Professor)

95. Liang, S. H., Wang, L., Stephenson, N. A., Rotstein, B. H., and Vasdev, N. “Facile 18F Labeling of Non-activated Arenes via a Spirocyclic Iodonium(III) Ylide Method and its Application in the Synthesis of the mGluR5 PET Radiopharmaceutical [18F]FPEB” Nature Protocol, 2019, 14, 1530-1545. 


94. Bernard-Gauthier, V., Mossine, A.V., Knight, A., Patnaik, D., Zhao, W., Cheng, C., Krishnan, H.S., Xuan, L.L., Chindavong, P.S., Reis, S.A., Chen, J.M., Shao, X., Stauff, J., Arteaga, J., Sherman, P.S., Salem, N., Bonsall, D., Amaral, B., Varlow, C., Wells, L., Martarello, L., Patel, S., Liang, S.H., Kurumbail, R.G., Haggarty, S.J., Scott, P.J.H. and Vasdev, N. “Structural Basis for Achieving GSK-3beta Inhibition with High Potency, Selectivity and Brain Exposure for PET Imaging and Drug Discovery” Journal of Medicinal Chemistry, 2019, ASAP, DOI: 10.1021/acs.jmedchem.9b01030.


93. Chen, Z., Mori, W., Fu, H., Schafroth, M. A., Hatori, A., Shao, T., Zhang, G., Van, R. S., Zhang, Y., Hu, K., Fujinaga, M., Wang, L., Belov, V., Ogasawara, D., Giffenig, P., Deng, X., Rong, J., Yu, Q., Zhang, X., Papisov, M. I., Shao, Y., Collier, T. L., Ma, J.-A., Cravatt, B. F., Josephson, L., Zhang, M.-R., and Liang, S. H. “Design, Synthesis and Evaluation of 18F-labeled Monoacylglycerol lipase Inhibitors as Novel Positron Emission Tomography Probes” Journal of Medicinal Chemistry, 2019, 62, 8866-8872.   https://pubmed.ncbi.nlm.nih.gov/31518130/


92. Nie, B., Wang, L., Hu, Y., Liang, S., Tan, Z., Chai, P., Tang, Y., Shang, J., Pan, Z., Zhao, X., Zhang, X., Gong, J., Zheng, C., Xu, H., Wey, H.-Y., Liang, S. H., and Shan, B. “A population stereotaxic positron emission tomography brain template for the macaque and its application to ischemic model” NeuroImage, 2019, ASAP, DOI: 10.1016/j.neuroimage.2019.116163


91. Chen, Z., Shao, T., Gao, W., Fu, H., Collier, T. L., Rong, J., Deng, X., Yu, Q., Zhang, X., Davenport, A. T., Daunais, J. B., Wey, H. Y., Shao, Y., Josephson, L., Qiu, W., and Liang, S. H.  “Synthesis and Preliminary Evaluation of [11C]GNE-1023 as a Potent PET Probe for Imaging Leucine-Rich Repeat Kinase 2 (LRRK2) in Parkinson’s Disease” ChemMedChem2019, 14, 1580-1585.

  Highlighted as Neuromedicine Hot Topics by ChemMedChem  


90. Zhang, B., Fraser, B. H., Klenner, M. A., Chen, Z., Liang, S. H., Massi, M., Robinson, A. J. and Pascali, G.  “[18F]Ethenesulfonyl fluoride as a novel radiofluoride relay reagent” Chemistry – A European Journal, 2019, accepted. https://onlinelibrary.wiley.com/doi/abs/10.1002/chem.201900930


89. Chen, Z., Mori, W., Deng, X., Cheng, R., Ogasawara, D., Zhang, G., Schafroth, M. A., Dahl, K., Fu, H., Hatori, A., Shao, T., Zhang, Y., Yamasaki, T., Zhang, X., Rong, J., Yu, Q., Hu, K., Fujinaga, M., Xie, L., Kumata, K., Gou, Y., Chen, J., Gu, S., Bao, L., Wang, L., Collier, T. L., Vasdev, N., Shao, Y., Ma, J.-A., Cravatt, B. F., Fowler, C., Josephson, L., Zhang, M.-R. and Liang, S. H.  “Design, Synthesis and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a ‘Tail Switching’ Strategy on a Piperazinyl Azetidine Skeleton”  Journal of Medicinal Chemistry, 2019, 62, 3336-3353. DOI: 10.1021/acs.jmedchem.8b01778.  PMC: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581563/


88. Ran, C., Yang, J., Cheng, R., Fu, H., Yang, J., Kumar, M., Lu, J., Xu, Y., Liang, S. H., and Cui, M.  “Half-curcumin analogues as PET imaging probes for Amyloid beta species” Chemical Communications, 2019, ASAP, DOI: 10.1039/c8cc10166c.


87. Shao, T., Josephson, L. and Liang, S. H. “PET/SPECT Molecular Probes for Diagnosis and Staging of Non-Alcoholic Fatty Liver Disease” Molecular Imaging, 2019, 18, 1-11. DOI: 10.1177/1536012119871455. 


86. Fu, H., Tang, W., Chen, Z., Belov, V., Zhang, G., Shao, T., Zhang, X., Yu, Q., Rong, J., Deng, X., Han, W., Myers, S., Giffenig, P., Wang, L., Josephson, L., Shao, Y., Davenport, A., Daunais, J., Papisov, M., Yuan, H., Li, Z., Traynelis, S. and Liang, S. H.  “Synthesis and Preliminary Evaluations of a Triazole-cored Antagonist ([18F]N2B-0518) as PET Imaging Probe for GluN2B Subunit in the Brain”  ACS Chemical Neuroscience, 2019, 10, 2263-2275.   DOI: 10.1021/acschemneuro.8b00591.


85. Deng, X., Hatori, A., Chen, Z., Kumata, K., Shao, T., Zhang, X., Yamasaki, T., Hu, K., Yu, Q., Ma, L., Wang, G., Wang, L., Shao, Y., Josephson, L., Sun, S., Zhang, M-R. and Liang, S. H.   “Synthesis and Preliminary Evaluation of 11C-Labeled VU0467485/AZ13713945 and Its Analogues for Imaging Muscarinic Acetylcholine Receptor Subtype 4″ ChemMedChem, 2019, 14, 303-309. DOI: 10.1002/cmdc.201800710.

  • This work is highlighted as Journal Cover and in the Neuromedicine Hot Topics by ChemMedChem.