We have a lot of exciting research activities commencing this year and a great team to do get it all done.
The epigenetic landscape in children the were born very preterm – This year we’ll be generating longitudinal DNA methylation data in our NOVI cohort, and begin to study how epigenetic trajectories track with developmental impairments. We also have ongoing research projects on the perinatal factors that impact neonatal epigenetic age acceleration, the early-life age-associated changes in the methylome, and the impacts of bronchopulmonary dysplasia.
Environmental impacts on placental molecular activity – We are also kicking off our recently awarded ViCTER project, to examine how prenatal exposure to per- and polyfluoroalkyl substances (PFAS) impact placental multi-omic profiles, and children’s growth and metabolic programming.
Pilot Projects – We are also engaged in two pilot projects, focused on how environmental exposures impact the epigenetic profiles within follicular fluid, and to examine how micro-RNA and DNA methylation vary in response to early life abusive injuries.