15 Good Minutes: Stefan Sarafianos
Stefan Sarafianos is the rare researcher whose expertise spans structural biology, biochemistry, and virology. He recently led the groundbreaking development of a SARS-CoV-2 subgenomic replicon system, including mutants, that can be used for high-throughput screening and characterization of SARS-CoV-2 replicase inhibitors at a lower biosafety level—considerable benefits for pursuing studies such as drug discovery and inhibitors assay. Many of us are familiar with the bedeviling question: “Do you want it faster, cheaper, and better? Pick one.” In the case of the replicon system Stefan Sarafianos has developed, researchers studying SARS-CoV-2 are able to benefit from all three and add one Read More …