Lau JY et al. 2007. Omeprazole before endoscopy in patients with gastrointestinal bleeding. NEJM. 356:1631-40. Take home points: 638 patients with upper GI bleed undergoing endoscopy were randomized to receive omeprazole vs placebo. The patients who received omeprazole prior to endoscopy had less need for intervention during endoscopy, fewer actively bleeding ulcers. A higher percentage …
