Dr. Andre Holder has an ongoing project that could be used as a practicum opportunity.

The purpose of this project is to conduct a systematic review of all clinical decision support systems used to predict sepsis or its sequelae (e.g., septic shock). We are searching the EMbase and PubMed databases for literature published from 2000 through late 2019. Manuscripts will be included if they include automated prediction of sepsis or associated organ failure. To differentiate from existing systematic reviews, we will focus on manuscripts that were published with a methodology that is reproducible in real-time. Furthermore, we only manuscripts that provide more than a simple area under the receiver operator curve; we would like to report useful performance metrics such as specificity or positive predictive value that accurately portray their utility in clinical practice. Manuscripts will undergo two levels of screening (titles, followed by abstracts and full manuscripts). Pertinent data including patient characteristics, outcomes of interest, performance metrics will be extracted from each manuscript. Reviewers will also be asked to make subjective estimations of bias per the QUADAS guidelines. 

Those who use this project as their practicum will be responsible for the following tasks:

·         Participate in a full review of all included manuscripts, including assessment of bias

·         Help with data analysis and summarizing conclusions

·         Perform a literature review of recent systematic reviews in this area

·         Assist with drafting the final manuscript

If interested please contact Andre Holder, MD, MS at andre [dot] holder [at] emory [dot] edu.