EH 720: Introduction to Physiologically-Based Toxicokinetic/Pharmacokinetic Modeling

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EH 720: Introduction to Physiologically-Based Toxicokinetic/Pharmacokinetic Modeling

Category : Academic Student Opportunities

Description 

There is still space available to register in EHS 720: Introduction to Physiologically-Based Toxicokinetic (PBTK)/Pharmacokinetic (PBPK) Modeling with Dr. Qiang Zhang!

The health effects of environmental or pharmaceutical chemicals depend on the concentrations of the xenobiotics and their metabolites in the target tissues. Understanding and predicting chemical internal concentrations (tissue dosimetry) requires a physiologically-based toxicokinetic (PBTK) or pharmacokinetic (PBPK) modeling approach. Based on human physiology and anatomy, PBTK/PBPK models mechanistically simulate the absorption, distribution, metabolism, and elimination (ADME) processes that affect the fates of exogenous chemicals in the human body, producing, as model output, changes in chemical tissue concentrations over time. PBTK/PBPK modeling has be increasingly applied in chemical health risk assessment and drug development. Students will learn numerical simulation tools to model what the body does to the chemicals in this course. It targets:

  • Environmental health science students interested in chemical tissue dosimetry, internal exposure, interpretation of biomarkers of exposures, in vitro to in vivo extrapolation (IVIVE) of chemical dosimetry
  • Pharmacology/toxicology students interested in quantitative simulation of tissue- specific drug dosimetry beyond classical, compartmental PK.
  • Students and researchers in biosciences, nutritional science, anesthesiology, biomedical engineering, and chemical engineering interested in computational approaches to predicting tissue concentrations of environmental, industrial, dietary, and pharmaceutical chemicals.

 

See the flyer below for more information about this spring course!

 

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  • GCDTR Seminar Series Presents: "Utilizing Genomics to Study the Role of Ancestry in Racial Disparities" May 6, 2024 at 12:00 am – 1:00 am Guest Lecture Event Type: Guest LectureSeries: HybridSpeaker: Melissa B. Davis, PhDContact Name: Wendy GillContact Email: wggill@emory.eduRoom Location: RRR_R809Link: https://tinyurl.com/Melissa-Davis"Utilizing Genomics to Study the Role of Ancestry in Racial Disparities"
  • 2024 Charles C. Shepard Award Symposium May 8, 2024 at 12:00 pm – 1:15 pm zoom.us… Online Location: https://zoom.us/j/96537866614The Charles C. Shepard Award is given to thegraduating masters student who is deemed bythe faculty to have prepared the most scholarlyresearch paper. Please join us to recognize andcelebrate this year’s finalists who will present aposter of their work.
  • RSPH Staff Council Presents: Cheers and Beers - Schoolhouse Edition May 16, 2024 at 5:00 pm – 8:00 pm Networking and Special Event Event Type: Networking,Special EventContact Name: Staff CouncilContact Email: rsphstaffcouncil@emory.eduRSPH staff and post-docs are invited to an evening of camaraderie and delicious bites, presented by the RSPH Staff Council. Space is limited. Watch your email for a link to RSVP.
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