Clinical question / background: In patients with ROSC following cardiac arrest, does cooling patients to 33 degrees Celsius increase the rate of survival after resuscitation compared to cooling to 36 degrees Celsius? Design: Unblinded, parallel-group, randomized, controlled trial 939 participants in 36 European and Australian centers Inclusion criteria: Witnessed arrest Unconscious at presentation Presumed cardiac …
Category: Cardiology
Jan 20
Lit of the Week – Therapeutic Hypothermia
Holzer M, et al. “Mild Therapeutic Hypothermia to Improve the Neurologic Outcome After Cardiac Arrest”. The New England Journal of Medicine. 2002. 346(8):549-556. Clinical question / background: In patients with ROSC following cardiac arrest due to ventricular fibrillation, does mild systemic hypothermia increase the rate of neurologic recovery after resuscitation? Design: Unblinded, parallel-group, …