May 19
Lit of the Week – 5/3/16 Glasgow Blatchford Bleeding Score Blatchford O, Murray WR, Blatchford M. A risk score to predict need for treatment for upper-gastrointestinal haemorrhage. Lancet. 2000 Oct 14;356(9238):1318-21. PubMed PMID: 11073021 Clinical question / background: Can a risk score based on medical history, hemodynamic variables, and simple lab data …
May 17
“NEXUS Chest – Validation of a Decision Instrument for Selective Chest Imaging in Blunt Trauma” http://www.ncbi.nlm.nih.gov/pubmed/23925583 Clinical question / background: Low yield radiology is costly and exposes patients to unnecessary radiation. Can the previously described NEXUS Chest Imaging rules be validated for clinical use in cases of blunt chest trauma? Very low risk for chest trauma …
Apr 29
Lit of the Week – 4/26/16 SOAP II: Comparison of Dopamine and Norepinephrine in the Treatment of Shock De Backer D, Biston P, Devriendt J, Madl C, Chochrad D, Aldecoa C, Brasseur A, Defrance P, Gottignies P, Vincent JL; SOAP II Investigators. Comparison of dopamine and norepinephrine in the treatment of shock. N Engl J …
Apr 19
Lit of the Week – 4/19/16 Talan DA, Mower WR, Krishnadasan A, Abrahamian FM, Lovecchio F, Karras DJ,Steele MT, Rothman RE, Hoagland R, Moran GJ. Trimethoprim-Sulfamethoxazole versus Placebo for Uncomplicated Skin Abscess. N Engl J Med. 2016 Mar 3;374(9):823-32. doi: 10.1056/NEJMoa1507476. PubMed PMID: 26962903. Clinical question / background: Compared to placebo, does administration trimethoprim-sulfamethoxazole …
Apr 19
Lit of the Week – 4/12/16 Kudenchuk PJ, Brown SP, Daya M, Rea T, Nichol G, Morrison LJ, Leroux B, Vaillancourt C, Wittwer L, Callaway CW, Christenson J, Egan D, Ornato JP, Weisfeldt ML, Stiell IG, Idris AH, Aufderheide TP, Dunford JV, Colella MR, Vilke GM, Brienza AM, Desvigne-Nickens P, Gray PC, Gray R, Seals …
Apr 12
“The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections” Clinical question / background: The goal of this study was to develop a diagnostic scoring system to distinguish necrotizing fasciitis from other soft tissue infections based on common laboratory evaluation. Design: Retrospective observational study. Chart …
Mar 29
Chi et al. “Prehospital Hypoxia Affects Outcome in Patients With Traumatic Brain Injury: A Prospective Multicenter Study.” J. Trauma. 2006;61:1134-1141 Clinical question / background: The goals of this study were to determine the incidence and duration of hypotension (SBP <90) and hypoxia (SpO2<92%) in the prehospital setting in patients with potentially survivable brain injuries, and …
Mar 29
Lit of the Week – 3/29/16 Rumack BH, Peterson RC, Koch GG, Amara IA. Acetaminophen overdose. 662 cases with evaluation of oral acetylcysteine treatment. Arch Intern Med. 1981 Feb 23;141(3 Spec No):380-5. PubMed PMID: 7469629. http://www.ncbi.nlm.nih.gov/pubmed/7469629 Clinical question / background: Does N-acetylcysteine prevent or moderate hepatotoxicity secondary to acute acetaminophen overdose? Design: …
Mar 22
Lit of the Week – 3/01/16 Stiell IG, Greenberg GH, McKnight RD, Nair RC, McDowell I, Reardon M, Stewart JP, Maloney J. Decision rules for the use of radiography in acute ankle injuries. Refinement and prospective validation. JAMA. 1993 Mar 3;269(9):1127-32. Clinical question / background: Can decision rules based on history and simple …
Mar 22
Patel MB, Humble SS, Cullinane DC, et al. Cervical spine collar clearance in the obtunded adult blunt trauma patient: a systematic review and practice management guideline from the Eastern Association for the Surgery of Trauma. J Trauma Acute Care Surg. 2015 Feb;78(2):430-41. Clinical question / background: In the obtunded blunt trauma patient, can cervical collar …